3-hydroxymethylphenytoin valproic acid ester

Known as: VAL-PHT 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2015
02419872015

Papers overview

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2008
2008
Portal hypertension (PHT) is a common complication of liver cirrhosis and significantly increases morbidity and mortality… (More)
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2004
2004
Lopinavir/ritonavir (LPV/RTV) is a CYP3A4 inhibitor and substrate; it also may induce cytochrome P-450 (CYP) isozymes. Phenytoin… (More)
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2002
2002
OBJECTIVE To evaluate postexposure prophylaxis (PEP) in dogs experimentally infected with rabies. ANIMALS 29 Beagles… (More)
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2000
2000
PURPOSE We evaluated the anticonvulsant efficacy of topiramate (TPM), a structurally novel antiepileptic drug (AED), in amygdala… (More)
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1998
1998
Dexfenfluramine and fenfluramine greatly increase the risk of developing pulmonary hypertension (PHT). The mechanism of… (More)
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1996
1996
3-Hydroxymethylphenytoin valproic acid ester (VAL-PHT) was designed as a new prodrug combining valproic acid and phenytoin, two… (More)
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1995
1995
Status epilepticus was induced in rats by injecting a combination of dibutyryl-cAMP (db-cAMP) and ethylenediaminetetraacetic acid… (More)
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1990
1990
Free and total carbamazepine (CBZ) and carbamazepine-epoxide (CBZ-EP) plasma levels were obtained on 113 patients with epilepsy… (More)
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1990
1990
Antineoplastic drugs are known to affect the intestinal wall and suppress the absorption of phenytoin (PHT), resulting in a… (More)
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1987
1987
Portal hypertension (PHT) is known to be associated with a hyperdynamic circulation, yet the pathogenesis of both remains unclear… (More)
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