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3-hydroxymethylphenytoin valproic acid ester

Known as: VAL-PHT 
 
National Institutes of Health

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2 relations

Broader (1)

Valproic Acid
analogs & derivatives

Papers overview

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2017
2017
Significant HLA class I type associations with aromatic antiepileptic drug (AED)‐induced SJS/TEN are different from those found for the same AED‐induced DRESS in the Spanish population
Graphical abstract Figure. No caption available. ABSTRACT Aromatic antiepileptic drugs (AEDs) are among the drugs most frequently… Expand
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Highly Cited
2013
Highly Cited
2013
Assessing physiological tipping point of sea urchin larvae exposed to a broad range of pH.
Our ability to project the impact of global change on marine ecosystem is limited by our poor understanding on how to predict… Expand
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2010
2010
Effects of Rho-Kinase Inhibition on Pulmonary Hypertension, Lung Growth, and Structure in Neonatal Rats Chronically Exposed to Hypoxia
Rho-kinase (ROCK) inhibitors prevent pulmonary hypertension (PHT) in adult rodents, but little is known about their effects on… Expand
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Highly Cited
2008
Highly Cited
2008
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population.
PURPOSE Previous studies found a strong association between HLA-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome… Expand
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2008
2008
Role of cyclooxygenase isoforms in prostacyclin biosynthesis and murine prehepatic portal hypertension.
Portal hypertension (PHT) is a common complication of liver cirrhosis and significantly increases morbidity and mortality… Expand
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Highly Cited
2006
Highly Cited
2006
Bosentan, Sildenafil, and Their Combination in the Monocrotaline Model of Pulmonary Hypertension in Rats
The dual endothelin receptor antagonist, bosentan, and the phosphodiesterase inhibitor, sildenafil, are efficacious in… Expand
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2002
2002
Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism.
Endothelin-1 (ET-1) mediates the development of pulmonary hypertension (PHT) in newborn rats exposed to 60% O(2) for 14 days, a… Expand
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1999
1999
Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleed: preliminary report of a randomized controlled trial.
BACKGROUND Prevention of variceal bleeding, a major cause of morbidity and mortality, is an important goal in the management of… Expand
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1998
1998
Evaluation of the safety, immunogenicity, and pharmacokinetic profile of a new, highly purified, heat-treated equine rabies immunoglobulin, administered either alone or in association with a purified…
A clinical evaluation of a new, purified, heat-treated equine rabies immunoglobulin (PHT-Erig), F(ab')2 preparation, was carried… Expand
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1987
1987
Vascular reactivity in experimental portal hypertension.
Portal hypertension (PHT) is known to be associated with a hyperdynamic circulation, yet the pathogenesis of both remains unclear… Expand
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