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VP-16

Known as: VP16, drug vp 16, VP 16 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Etoposide

Papers overview

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Highly Cited
1999
Highly Cited
1999
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.
Highly Cited
1995
Highly Cited
1995
Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro.
The CBP protein mediates PKA induced transcription by binding to the PKA phosphorylated activation domain of CREB. Here we show… 
Highly Cited
1995
Highly Cited
1995
CBP‐induced stimulation of c‐Fos activity is abrogated by E1A.
The CBP protein stimulates transcription of cAMP‐responsive genes by binding to the phosphorylated activation domain of the CREB… 
Highly Cited
1994
Highly Cited
1994
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor
Highly Cited
1994
Highly Cited
1994
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53
Acidic transcriptional activation domains function well in both yeast and mammalian cells, and some have been shown to bind the… 
Highly Cited
1993
Highly Cited
1993
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB
Highly Cited
1990
Highly Cited
1990
Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID
The potent transactivation domain of the herpes simplex virion protein VP16 was used as a column ligand for affinity… 
Highly Cited
1988
Highly Cited
1988
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.
Mature virions of herpes simplex virus type 1 contain an activating factor that primes transcription from the five virally… 
Highly Cited
1988
Highly Cited
1988
A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.
A full-length cDNA for the human multidrug resistance gene 1 (MDR1) has been inserted into a retroviral vector containing a… 
Review
1985
Review
1985
Etoposide (VP-16-213). Current status of an active anticancer drug.
IN the 12 years since its introduction into clinical trials in the United States, etoposide (VP-16–213; epipodophyllotoxin; 4… 
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