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VACA protocol

Known as: CTX/DACT/DOX/VCR, Cyclophosphamide/Dactinomycin/Doxorubicin/Vincristine, CY-VA-DACT 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDactinomycincisplatin/cyclophosphamide/etoposide protocol
DoxorubicinDoxorubicin HydrochlorideVincristine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Cortactin Mediates Apoptosis of Gastric Epithelial Cells Induced by VacA Protein of Helicobacter pylori
BackgroundVacuolating cytotoxin antigen (VacA) is one of the major virulence factors in Helicobacter pylori (H. pylori), which is… 
2012
2012
The Intermediate Region of Helicobacter pylori VacA Is a Determinant of Toxin Potency in a Jurkat T Cell Assay
ABSTRACT Colonization of the human stomach with Helicobacter pylori is a risk factor for peptic ulceration, noncardia gastric… 
Review
2010
Review
2010
Pleiotropic actions of Helicobacter pylori vacuolating cytotoxin, VacA.
Helicobacter pylori produces a vacuolating cytotoxin, VacA, and most virulent H. pylori strains secrete VacA. VacA binds to two… 
2008
2008
Involvement of Vesicle-Associated Membrane Protein 7 in Human Gastric Epithelial Cell Vacuolation Induced by Helicobacter pylori-Produced VacA
ABSTRACT Helicobacter pylori-produced cytotoxin VacA induces intracellular vacuolation. The VacA-induced vacuole is assumed to… 
Highly Cited
2004
Highly Cited
2004
Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin.
Helicobacter pylori VacA is a secreted protein toxin that may contribute to the pathogenesis of peptic ulcer disease and gastric… 
2000
2000
Structure and interaction of VacA of Helicobacter pylori with a lipid membrane.
In its mature form, the VacA toxin of Helicobacter pylori is a 95-kDa protein which is released from the bacteria as a low… 
Highly Cited
1999
Highly Cited
1999
Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation.
Highly Cited
1999
Highly Cited
1999
Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity.
Polarized epithelial monolayers of Madin-Darby canine kidney (MDCK) cells were used to study the pathogenicity of Helicobater… 
Highly Cited
1999
Highly Cited
1999
Inhibition of the vacuolating and anion channel activities of the VacA toxin of Helicobacter pylori
Highly Cited
1997
Highly Cited
1997
Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol
Cells exposed to Helicobacter pylori toxin VacA develop large vacuoles that originate from massive swelling of membranous… 
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