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VACA protocol

Known as: CTX/DACT/DOX/VCR, Cyclophosphamide/Dactinomycin/Doxorubicin/Vincristine, CY-VA-DACT 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDactinomycincisplatin/cyclophosphamide/etoposide protocol
DoxorubicinDoxorubicin HydrochlorideVincristine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis
More than 50% of the world's population is infected with Helicobacter pylori (H. pylori). Chronic infection with this Gram… 
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Review
2010
Review
2010
Pleiotropic actions of Helicobacter pylori vacuolating cytotoxin, VacA.
Helicobacter pylori produces a vacuolating cytotoxin, VacA, and most virulent H. pylori strains secrete VacA. VacA binds to two… 
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Highly Cited
2006
Highly Cited
2006
Impact of Plug-in Hybrid Vehicles on the Electric Grid
Plug-in hybrid vehicles (PHEVs) are being developed around the world; much work is going on to optimize engine and battery… 
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Highly Cited
2006
Highly Cited
2006
Helicobacter pylori Vacuolating Cytotoxin Induces Activation of the Proapoptotic Proteins Bax and Bak, Leading to Cytochrome c Release and Cell Death, Independent of Vacuolation*
Helicobacter pylori vacuolating cytotoxin, VacA, which causes vacuolation of gastric epithelial cells and other types of cultured… 
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Highly Cited
2004
Highly Cited
2004
Helicobacter pylori toxin VacA is transferred to host cells via a novel contact‐dependent mechanism
Helicobacter pylori is the causative agent of peptic ulcer disease. A major virulence factor of H. pylori is VacA, a toxin that… 
Highly Cited
2004
Highly Cited
2004
Helicobacter pylori VacA Activates the p38/Activating Transcription Factor 2-mediated Signal Pathway in AZ-521 Cells*
Persistent Helicobacter pylori colonization in the stomach induces gastritis and peptic ulcer and interferes with ulcer healing… 
Highly Cited
1999
Highly Cited
1999
Formation of anion‐selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
The vacuolating toxin VacA, a major determinant of Helicobacter pylori‐associated gastric diseases, forms anion‐selective… 
Highly Cited
1999
Highly Cited
1999
Activation of Helicobacter pylori VacA Toxin by Alkaline or Acid Conditions Increases Its Binding to a 250-kDa Receptor Protein-tyrosine Phosphatase β*
Helicobacter pylori, a Gram-negative gastric bacterium, secretes VacA, a cytotoxin that causes vacuolar degeneration of… 
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Highly Cited
1999
Highly Cited
1999
Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity.
Polarized epithelial monolayers of Madin-Darby canine kidney (MDCK) cells were used to study the pathogenicity of Helicobater… 
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Highly Cited
1997
Highly Cited
1997
Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol
Cells exposed to Helicobacter pylori toxin VacA develop large vacuoles that originate from massive swelling of membranous… 
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