VACA protocol

Known as: CTX/DACT/DOX/VCR, Cyclophosphamide/Dactinomycin/Doxorubicin/Vincristine, CY-VA-DACT 
 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDactinomycincisplatin/cyclophosphamide/etoposide protocol
DoxorubicinDoxorubicin HydrochlorideVincristine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Intoxication strategy of Helicobacter pylori VacA toxin.
VacA toxin from the cancer-inducing bacterium Helicobacter pylori is currently classified as a pore-forming toxin but is also… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Review
2012
Review
2012
Remodeling the host environment: modulation of the gastric epithelium by the Helicobacter pylori vacuolating toxin (VacA)
Virulence mechanisms underlying Helicobacter pylori persistence and disease remain poorly understood, in part, because the… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Review
2010
Review
2010
Pleiotropic actions of Helicobacter pylori vacuolating cytotoxin, VacA.
Helicobacter pylori produces a vacuolating cytotoxin, VacA, and most virulent H. pylori strains secrete VacA. VacA binds to two… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
A Tale of Two Toxins: Helicobacter Pylori CagA and VacA Modulate Host Pathways that Impact Disease
Helicobacter pylori is a pathogenic bacterium that colonizes more than 50% of the world's population, which leads to a tremendous… (More)
  • figure 1
  • figure 2
Is this relevant?
2008
2008
Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein…
Helicobacter pylori VacA induces multiple effects on susceptible cells, including vacuolation, mitochondrial damage, inhibition… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes.
The vacuolating cytotoxin VacA is a major virulence factor of Helicobacter pylori, a bacterium responsible for gastroduodenal… (More)
Is this relevant?
Review
2002
Review
2002
Pathogenesis of Helicobacter pylori infection.
Five years after publication of the complete genome sequence of Helicobacter pylori, research interest is shifting from the… (More)
Is this relevant?
2001
2001
Dynamin is involved in human epithelial cell vacuolation caused by the Helicobacter pylori-produced cytotoxin VacA.
The Helicobacter pylori-produced cytotoxin VacA induces intracellular vacuolation. To elucidate the molecular mechanism of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity.
The vacuolating toxin VacA, a major determinant of Helicobacter pylori-associated gastric diseases, forms anion-selective… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1999
1999
Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity.
Polarized epithelial monolayers of Madin-Darby canine kidney (MDCK) cells were used to study the pathogenicity of Helicobater… (More)
  • table I
  • figure 1
  • figure 2
  • figure 5
  • figure 3
Is this relevant?