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VACA protocol

Known as: CTX/DACT/DOX/VCR, Cyclophosphamide/Dactinomycin/Doxorubicin/Vincristine, CY-VA-DACT 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDactinomycincisplatin/cyclophosphamide/etoposide protocol
DoxorubicinDoxorubicin HydrochlorideVincristine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis
More than 50% of the world's population is infected with Helicobacter pylori (H. pylori). Chronic infection with this Gram… 
Highly Cited
2007
Highly Cited
2007
Red wine and green tea reduce H pylori- or VacA-induced gastritis in a mouse model.
AIM To investigate whether red wine and green tea could exert anti-H pylori or anti-VacA activity in vivo in a mouse model of… 
Highly Cited
2006
Highly Cited
2006
Impact of Plug-in Hybrid Vehicles on the Electric Grid
Plug-in hybrid vehicles (PHEVs) are being developed around the world; much work is going on to optimize engine and battery… 
Highly Cited
2006
Highly Cited
2006
Helicobacter pylori Vacuolating Cytotoxin Induces Activation of the Proapoptotic Proteins Bax and Bak, Leading to Cytochrome c Release and Cell Death, Independent of Vacuolation*
Helicobacter pylori vacuolating cytotoxin, VacA, which causes vacuolation of gastric epithelial cells and other types of cultured… 
Highly Cited
2005
Highly Cited
2005
Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes.
The vacuolating cytotoxin VacA is a major virulence factor of Helicobacter pylori, a bacterium responsible for gastroduodenal… 
Highly Cited
2004
Highly Cited
2004
Helicobacter pylori VacA Activates the p38/Activating Transcription Factor 2-mediated Signal Pathway in AZ-521 Cells*
Persistent Helicobacter pylori colonization in the stomach induces gastritis and peptic ulcer and interferes with ulcer healing… 
Highly Cited
1999
Highly Cited
1999
Formation of anion‐selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
The vacuolating toxin VacA, a major determinant of Helicobacter pylori‐associated gastric diseases, forms anion‐selective… 
Highly Cited
1999
Highly Cited
1999
Activation of Helicobacter pylori VacA Toxin by Alkaline or Acid Conditions Increases Its Binding to a 250-kDa Receptor Protein-tyrosine Phosphatase β*
Helicobacter pylori, a Gram-negative gastric bacterium, secretes VacA, a cytotoxin that causes vacuolar degeneration of… 
Highly Cited
1998
Highly Cited
1998
The acid activation of Helicobacter pylori toxin VacA: structural and membrane binding studies.
The cell vacuolating activity of the protein toxin VacA, released by Helicobacter pylori, is strongly increased in vitro by… 
Highly Cited
1997
Highly Cited
1997
Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol
Cells exposed to Helicobacter pylori toxin VacA develop large vacuoles that originate from massive swelling of membranous… 
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