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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… Expand
National Institutes of Health

Related topics

Related topics

47 relations

Broader (1)

Antineoplastic Agents, Phytogenic

Narrower (15)

B-DOMP protocolCCV protocolCEOP-B protocolCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristine
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CEV regimenCMFVP protocolCOPAD protocolCOPP-ABV Regimen
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Mechanisms of Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects caused by antineoplastic agents, with… Expand
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Review
2017
Review
2017
Glioma Subclassifications and Their Clinical Significance
The impact of targeted therapies in glioma has been modest. All the therapies that have demonstrated a significant survival… Expand
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Highly Cited
2016
Highly Cited
2016
Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death… Expand
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Highly Cited
2013
Highly Cited
2013
Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.
PURPOSE Anaplastic oligodendroglioma are chemotherapy-sensitive tumors. We now present the long-term follow-up findings of a… Expand
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Highly Cited
2009
Highly Cited
2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared… Expand
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Highly Cited
2004
Highly Cited
2004
Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy
&NA; Paclitaxel (Taxol®) is one of the most effective and frequently used chemotherapeutics for the treatment of solid tumours… Expand
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Highly Cited
2002
Highly Cited
2002
CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma
Background The standard treatment for patients with diffuse large-B-cell lymphoma is cyclophosphamide, doxorubicin, vincristine… Expand
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Highly Cited
2002
Highly Cited
2002
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
Diffuse large B-cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is curable in less than 50% of patients… Expand
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Highly Cited
2000
Highly Cited
2000
Group
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book… Expand
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Highly Cited
1981
Highly Cited
1981
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.
A noncytotoxic dose of verapamil, a coronary vasodilator, enhances the cytotoxicity of vincristine (VCR) and vinblastine in P388… Expand
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