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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… 
National Institutes of Health

Related topics

Related topics

47 relations

Broader (1)

Antineoplastic Agents, Phytogenic

Narrower (14)

B-DOMP protocolCCV protocolCEOP-B protocolCOFP protocol 1
CEV regimenCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristineCMFVP protocolCOPAD protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial
Highly Cited
2014
Highly Cited
2014
Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH.
PURPOSE Patients with 1p/19q codeleted anaplastic oligodendroglial tumors who participated in RTOG (Radiation Therapy Oncology… 
Review
2012
Review
2012
An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
Tubulin dynamics is a promising target for new chemotherapeutic agents. The colchicine binding site is one of the most important… 
Highly Cited
2006
Highly Cited
2006
Chemoimmunotherapy with hyper‐CVAD plus rituximab for the treatment of adult Burkitt and Burkitt‐type lymphoma or acute lymphoblastic leukemia
Adult Burkitt‐type lymphoma (BL) and acute lymphoblastic leukemia (B‐ALL) are rare entities composing 1% to 5% of non‐Hodgkin… 
Review
1999
Review
1999
Looping versus linking: toward a model for long-distance gene activation.
Locus control regions (LCRs) are defined by their ability, in transgenic assays, to direct high-level, tissue-specific expression… 
Highly Cited
1996
Highly Cited
1996
Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma.
PURPOSE To compare the safety and efficacy of liposomal daunorubicin (DaunoXome; NeXstar Pharmaceuticals, Inc, Boulder, CO) with… 
Highly Cited
1996
Highly Cited
1996
Prospective comparison of openvs. laparoscopic colon surgery for carcinoma
Laparoscopy for colonic diseases began in 1990 and has established a role in benign disease. Early observations and experiences… 
Highly Cited
1990
Highly Cited
1990
The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone.
In a prospective randomized trial designed to study the effectiveness of adjuvant chemotherapy following standard surgical… 
Highly Cited
1988
Highly Cited
1988
Malignant pheochromocytoma: effective treatment with a combination of cyclophosphamide, vincristine, and dacarbazine.
STUDY OBJECTIVE To determine the efficacy and toxicity of combination chemotherapy in patients with advanced, malignant… 
Highly Cited
1973
Highly Cited
1973
Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells.
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