Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2018
020040060080019552017

Papers overview

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Highly Cited
2013
Highly Cited
2013
PURPOSE Anaplastic oligodendroglioma are chemotherapy-sensitive tumors. We now present the long-term follow-up findings of a… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To compare the long-term outcome of patients with previously untreated follicular lymphoma (FL) needing therapy, after… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Anaplastic oligodendrogliomas are more responsive to chemotherapy than high-grade astrocytomas. We investigated, in a… (More)
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Highly Cited
2005
Highly Cited
2005
Phase 2 studies suggest that the monoclonal antibody rituximab may improve the prognosis of patients with follicular lymphoma (FL… (More)
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Highly Cited
2004
Highly Cited
2004
Paclitaxel (Taxol) is one of the most effective and frequently used chemotherapeutics for the treatment of solid tumours. However… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The standard treatment for patients with diffuse large-B-cell lymphoma is cyclophosphamide, doxorubicin, vincristine… (More)
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Highly Cited
2002
Highly Cited
2002
Diffuse large B-cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is curable in less than 50% of patients… (More)
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Highly Cited
1982
Highly Cited
1982
Some calcium antagonists and calmodulin inhibitors enhance the intracellular levels of vincristine and Adriamycin in vincristine… (More)
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Highly Cited
1981
Highly Cited
1981
A noncytotoxic dose of verapamil, a coronary vasodilator, enhances the cytotoxicity of vincristine (VCR) and vinblastine in P388… (More)
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