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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… Expand
National Institutes of Health

Related topics

Related topics

47 relations

Broader (1)

Antineoplastic Agents, Phytogenic

Narrower (15)

B-DOMP protocolCCV protocolCEOP-B protocolCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristine
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CEV regimenCMFVP protocolCOPAD protocolCOPP-ABV Regimen
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death… Expand
Highly Cited
2012
Highly Cited
2012
Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone.
PURPOSE Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with rituximab plus cyclophosphamide… Expand
Highly Cited
2009
Highly Cited
2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared… Expand
Highly Cited
2004
Highly Cited
2004
Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy
&NA; Paclitaxel (Taxol®) is one of the most effective and frequently used chemotherapeutics for the treatment of solid tumours… Expand
Highly Cited
2002
Highly Cited
2002
CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma
Background The standard treatment for patients with diffuse large-B-cell lymphoma is cyclophosphamide, doxorubicin, vincristine… Expand
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Highly Cited
2000
Highly Cited
2000
Group
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book… Expand
Review
1999
Review
1999
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer.
PURPOSE Topotecan and cyclophosphamide, doxorubicin, and vincristine (CAV) were evaluated in a randomized, multicenter study of… Expand
Highly Cited
1993
Highly Cited
1993
Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma.
BACKGROUND CHOP is a first-generation, combination-chemotherapy regimen consisting of cyclophosphamide, doxorubicin, vincristine… Expand
Highly Cited
1990
Highly Cited
1990
The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone.
In a prospective randomized trial designed to study the effectiveness of adjuvant chemotherapy following standard surgical… Expand
Highly Cited
1981
Highly Cited
1981
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.
A noncytotoxic dose of verapamil, a coronary vasodilator, enhances the cytotoxicity of vincristine (VCR) and vinblastine in P388… Expand
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