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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death… Expand
Highly Cited
2012
Highly Cited
2012
PURPOSE Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with rituximab plus cyclophosphamide… Expand
Highly Cited
2009
Highly Cited
2009
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared… Expand
Highly Cited
2004
Highly Cited
2004
&NA; Paclitaxel (Taxol®) is one of the most effective and frequently used chemotherapeutics for the treatment of solid tumours… Expand
Highly Cited
2002
Highly Cited
2002
Background The standard treatment for patients with diffuse large-B-cell lymphoma is cyclophosphamide, doxorubicin, vincristine… Expand
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Highly Cited
2000
Highly Cited
2000
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book… Expand
Review
1999
Review
1999
PURPOSE Topotecan and cyclophosphamide, doxorubicin, and vincristine (CAV) were evaluated in a randomized, multicenter study of… Expand
Highly Cited
1993
Highly Cited
1993
BACKGROUND CHOP is a first-generation, combination-chemotherapy regimen consisting of cyclophosphamide, doxorubicin, vincristine… Expand
Highly Cited
1990
Highly Cited
1990
In a prospective randomized trial designed to study the effectiveness of adjuvant chemotherapy following standard surgical… Expand
Highly Cited
1981
Highly Cited
1981
A noncytotoxic dose of verapamil, a coronary vasodilator, enhances the cytotoxicity of vincristine (VCR) and vinblastine in P388… Expand
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