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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… 
National Institutes of Health

Related topics

Related topics

47 relations

Broader (1)

Antineoplastic Agents, Phytogenic

Narrower (14)

B-DOMP protocolCCV protocolCEOP-B protocolCOFP protocol 1
CEV regimenCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristineCMFVP protocolCOPAD protocol

Papers overview

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Highly Cited
2006
Highly Cited
2006
Acute promyelocytic leukemia with, t( 15; 17) abnormality after, chemotherapy containing etoposide for, Langerhans cell histiocytosis
of their disease. Obviously, a randomized double-blind study is a much better design to assess drug efficacy. However, we… 
Highly Cited
2005
Highly Cited
2005
Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo
Tumor necrosis factor related apoptosis‐inducing ligand/Apo2 ligand (TRAIL/Apo‐2L) is a novel anticancer agent, capable of… 
Highly Cited
2001
Highly Cited
2001
Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse beta-globin LCR.
We employ real-time PCR to allow us to quantify the sensitivity of chromatin to digestion by DNaseI. This approach has three… 
Highly Cited
1995
Highly Cited
1995
Differential effects of deletions in lcrV on secretion of V antigen, regulation of the low-Ca2+ response, and virulence of Yersinia pestis
The Yersinia pestis V antigen is necessary for full induction of low-calcium response (LCR) stimulon virulence gene transcription… 
Highly Cited
1993
Highly Cited
1993
The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region.
Proper expression of the human beta‐like globin genes is completely dependent on the presence of the locus control region or LCR… 
Highly Cited
1987
Highly Cited
1987
Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein.
Highly Cited
1985
Highly Cited
1985
Gastrointestinal digestion and absorption of lipid.
  • P. Tso
  • 1985
  • Corpus ID: 260630590
Highly Cited
1982
Highly Cited
1982
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna).
Highly Cited
1977
Highly Cited
1977
Combination chemotherapy of advanced non-Hodgkin lymphoma with bleomycin, adriamycin, cyclophosphamide, vincristine, and prednisone (BACOP).
Seventy-three patients with advanced non-Hodgkin lymphoma were treated with bleomycin, Adriamycin, cyclophosphamide, vincristine… 
Highly Cited
1975
Highly Cited
1975
Interaction of Vinblastine with Calf Brain Microtubule protein.
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