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Vincristine
Known as:
VCR
, Vincristin
, 22-Oxovincaleukoblastine
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A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the…
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National Institutes of Health
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Related topics
Related topics
47 relations
Broader (1)
Antineoplastic Agents, Phytogenic
Narrower (15)
B-DOMP protocol
CCV protocol
CEOP-B protocol
CHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristine
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CEV regimen
CMFVP protocol
COPAD protocol
COPP-ABV Regimen
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.
J. Buckner
,
E. Shaw
,
+19 authors
W. Curran
New England Journal of Medicine
2016
Corpus ID: 205097726
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death…
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Highly Cited
2012
Highly Cited
2012
Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone.
N. Johnson
,
G. Slack
,
+28 authors
R. Gascoyne
Journal of Clinical Oncology
2012
Corpus ID: 46215447
PURPOSE Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with rituximab plus cyclophosphamide…
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Highly Cited
2009
Highly Cited
2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
W. Wick
,
C. Hartmann
,
+17 authors
M. Weller
Journal of Clinical Oncology
2009
Corpus ID: 10282460
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared…
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Highly Cited
2006
Highly Cited
2006
CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera…
M. Pfreundschuh
,
L. Trümper
,
+21 authors
M. Loeffler
The Lancet Oncology
2006
Corpus ID: 4657814
Review
2005
Review
2005
Plants as a source of anti-cancer agents.
G. Cragg
,
D. Newman
Journal of Ethnopharmacology
2005
Corpus ID: 636089
Highly Cited
2002
Highly Cited
2002
CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma
B. E. C. Oiffier
,
E. R. L. Epage
,
+10 authors
C. H. G. Isselbrecht
2002
Corpus ID: 51832913
Background The standard treatment for patients with diffuse large-B-cell lymphoma is cyclophosphamide, doxorubicin, vincristine…
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Highly Cited
2000
Highly Cited
2000
Group
P. F. Kauff
Elegant Design
2000
Corpus ID: 218773023
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book…
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Review
1999
Review
1999
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer.
J. von Pawel
,
J. Schiller
,
+12 authors
R. Gralla
Journal of Clinical Oncology
1999
Corpus ID: 1635032
PURPOSE Topotecan and cyclophosphamide, doxorubicin, and vincristine (CAV) were evaluated in a randomized, multicenter study of…
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Highly Cited
1997
Highly Cited
1997
Carboplatin and vincristine chemotherapy for children with newly diagnosed progressive low-grade gliomas.
R. Packer
,
J. Ater
,
+9 authors
J. Boyett
Journal of Neurosurgery
1997
Corpus ID: 8322000
The optimum treatment of nonresectable low-grade gliomas of childhood remains undecided. There has been increased interest in the…
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Highly Cited
1981
Highly Cited
1981
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.
T. Tsuruo
,
H. Iida
,
S. Tsukagoshi
,
Y. Sakurai
Cancer Research
1981
Corpus ID: 15484163
A noncytotoxic dose of verapamil, a coronary vasodilator, enhances the cytotoxicity of vincristine (VCR) and vinblastine in P388…
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