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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… 
National Institutes of Health

Related topics

Related topics

47 relations

Broader (1)

Antineoplastic Agents, Phytogenic

Narrower (14)

B-DOMP protocolCCV protocolCEOP-B protocolCOFP protocol 1
CEV regimenCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristineCMFVP protocolCOPAD protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Acute promyelocytic leukemia with, t( 15; 17) abnormality after, chemotherapy containing etoposide for, Langerhans cell histiocytosis
of their disease. Obviously, a randomized double-blind study is a much better design to assess drug efficacy. However, we… 
Highly Cited
2001
Highly Cited
2001
Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse beta-globin LCR.
We employ real-time PCR to allow us to quantify the sensitivity of chromatin to digestion by DNaseI. This approach has three… 
Highly Cited
1995
Highly Cited
1995
Differential effects of deletions in lcrV on secretion of V antigen, regulation of the low-Ca2+ response, and virulence of Yersinia pestis
The Yersinia pestis V antigen is necessary for full induction of low-calcium response (LCR) stimulon virulence gene transcription… 
Highly Cited
1993
Highly Cited
1993
The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region.
Proper expression of the human beta‐like globin genes is completely dependent on the presence of the locus control region or LCR… 
Highly Cited
1992
Highly Cited
1992
Neoadjuvant chemotherapy in 126 operable breast cancers.
Highly Cited
1985
Highly Cited
1985
Gastrointestinal digestion and absorption of lipid.
  • P. Tso
  • 1985
  • Corpus ID: 260630590
Highly Cited
1983
Highly Cited
1983
Alteration of plasma membrane glycopeptides and gangliosides of Chinese hamster cells accompanying development of resistance to daunorubicin and vincristine.
Abstract Glycoproteins and gangliosides of spontaneously transformed Chinese hamster lung cells (DC-3F) and of vincristine- and… 
Highly Cited
1977
Highly Cited
1977
Combination chemotherapy of advanced non-Hodgkin lymphoma with bleomycin, adriamycin, cyclophosphamide, vincristine, and prednisone (BACOP).
Seventy-three patients with advanced non-Hodgkin lymphoma were treated with bleomycin, Adriamycin, cyclophosphamide, vincristine… 
Highly Cited
1977
Highly Cited
1977
Maytansine binding to the vinblastine sites of tubulin
Highly Cited
1975
Highly Cited
1975
Interaction of Vinblastine with Calf Brain Microtubule protein.
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