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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death… 
Highly Cited
2012
Highly Cited
2012
PURPOSE Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with rituximab plus cyclophosphamide… 
Highly Cited
2009
Highly Cited
2009
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared… 
Review
2005
Review
2005
Highly Cited
2002
Highly Cited
2002
Background The standard treatment for patients with diffuse large-B-cell lymphoma is cyclophosphamide, doxorubicin, vincristine… 
Highly Cited
2000
Highly Cited
2000
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book… 
Review
1999
Review
1999
PURPOSE Topotecan and cyclophosphamide, doxorubicin, and vincristine (CAV) were evaluated in a randomized, multicenter study of… 
Highly Cited
1997
Highly Cited
1997
The optimum treatment of nonresectable low-grade gliomas of childhood remains undecided. There has been increased interest in the… 
Highly Cited
1981
Highly Cited
1981
A noncytotoxic dose of verapamil, a coronary vasodilator, enhances the cytotoxicity of vincristine (VCR) and vinblastine in P388…