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Vincristine

Known as: VCR, Vincristin, 22-Oxovincaleukoblastine 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the… 
National Institutes of Health

Related topics

Related topics

47 relations

Broader (1)

Antineoplastic Agents, Phytogenic

Narrower (15)

B-DOMP protocolCCV protocolCEOP-B protocolCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristine
CEV regimenCMFVP protocolCOPAD protocolCOPP-ABV Regimen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death… 
Highly Cited
2012
Highly Cited
2012
Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone.
PURPOSE Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with rituximab plus cyclophosphamide… 
Highly Cited
2009
Highly Cited
2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared… 
Highly Cited
2006
Highly Cited
2006
CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera…
Review
2005
Review
2005
Plants as a source of anti-cancer agents.
Highly Cited
2002
Highly Cited
2002
CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma
Background The standard treatment for patients with diffuse large-B-cell lymphoma is cyclophosphamide, doxorubicin, vincristine… 
Highly Cited
2000
Highly Cited
2000
Group
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book… 
Review
1999
Review
1999
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer.
PURPOSE Topotecan and cyclophosphamide, doxorubicin, and vincristine (CAV) were evaluated in a randomized, multicenter study of… 
Highly Cited
1997
Highly Cited
1997
Carboplatin and vincristine chemotherapy for children with newly diagnosed progressive low-grade gliomas.
The optimum treatment of nonresectable low-grade gliomas of childhood remains undecided. There has been increased interest in the… 
Highly Cited
1981
Highly Cited
1981
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.
A noncytotoxic dose of verapamil, a coronary vasodilator, enhances the cytotoxicity of vincristine (VCR) and vinblastine in P388… 
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