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Doxorubicin

Known as: Hydroxyldaunorubicin, 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-, Doxorubicin [Chemical/Ingredient] 
An anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the… 
National Institutes of Health

Related topics

Related topics

48 relations
AC-T RegimenCDE protocol-cyclophosphamide/doxorubicin/etoposideCHVmP-VB protocolCOPP-ABV Regimen
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Narrower (20)

ACP protocolCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristineCISCA protocolDOXO-cell
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems
Objectives  The frontline drug doxorubicin has been used for treating cancer for over 30 years. While providing a cure in select… 
Review
2005
Review
2005
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
Highly Cited
2003
Highly Cited
2003
Congestive heart failure in patients treated with doxorubicin
Doxorubicin is a highly effective and widely used cytotoxic agent with application that is limited by cardiotoxicity related to… 
Highly Cited
2001
Highly Cited
2001
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… 
Highly Cited
2000
Highly Cited
2000
Molecular portraits of human breast tumours
Human breast tumours are diverse in their natural history and in their responsiveness to treatments. Variation in transcriptional… 
Highly Cited
2000
Highly Cited
2000
Group
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book… 
Highly Cited
1998
Highly Cited
1998
Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies.
OBJECTIVE To estimate the incidence of serious and fatal adverse drug reactions (ADR) in hospital patients. DATA SOURCES Four… 
Review
1998
Review
1998
Doxorubicin-induced cardiomyopathy.
Doxorubicin (Adriamycin) has been used in oncologic practice since the late 1960s. It held promise as a powerful drug in the… 
Highly Cited
1981
Highly Cited
1981
A method for estimating the probability of adverse drug reactions
The estimation of the probability that a drug caused an adverse clinical event is usually based on clinical judgment. Lack of a… 
Highly Cited
1979
Highly Cited
1979
Risk factors for doxorubicin-induced congestive heart failure.
Potential risk factors responsible for development of doxorubicin-induced congestive heart failure were examined through… 
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