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Doxorubicin

Known as: Hydroxyldaunorubicin, 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-, Doxorubicin [Chemical/Ingredient] 
An anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the… 
National Institutes of Health

Related topics

Related topics

48 relations
AC-T RegimenCDE protocol-cyclophosphamide/doxorubicin/etoposideCHVmP-VB protocolCOPP-ABV Regimen

Narrower (20)

ACP protocolCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristineCISCA protocolDOXO-cell

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
A virus-mimetic nanogel vehicle.
Viruses infect specific cells within host organisms, replicate, destroy the cells, and spread from cell to cell in infectious… 
Highly Cited
2002
Highly Cited
2002
BRCA1 Directs a Selective p53-Dependent Transcriptional Response towards Growth Arrest and DNA Repair Targets
ABSTRACT The pathway leading to BRCA1-dependent tumor suppression is not yet clear but appears to involve activities in DNA… 
Highly Cited
2000
Highly Cited
2000
Inner core segment design for drug delivery control of thermo-responsive polymeric micelles.
Highly Cited
1993
Highly Cited
1993
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells.
Highly Cited
1991
Highly Cited
1991
A novel vitamin D3 analog, 22-oxa-1,25-dihydroxyvitamin D3, inhibits the growth of human breast cancer in vitro and in vivo without causing hypercalcemia.
Although 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] has been shown to inhibit the growth of certain malignant cells, its… 
Highly Cited
1978
Highly Cited
1978
Uptake and retention of adriamycin and daunorubicin by sensitive and anthracycline-resistant sublines of P388 leukemia.
Highly Cited
1977
Highly Cited
1977
Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… 
Highly Cited
1977
Highly Cited
1977
Transport and binding of daunorubicin, adriamycin, and rubidazone in Ehrlich ascites tumour cells.
Review
1976
Review
1976
Survey of radioactive agents for in vitro labeling of phagocytic leukocytes. I. Soluble agents.
Twenty-three soluble (nonparticulate) radioactive agents were screened for their ability to label leukocytes in vitro in the… 
Highly Cited
1975
Highly Cited
1975
A preparative synthesis of 3-amino-2,3,6-trideoxy-L-lyxo-hexose (daunosamine) hydrochloride from D-mannose.
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