Doxorubicin

Known as: Hydroxyldaunorubicin, 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-, Doxorubicin [Chemical/Ingredient] 
An anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the… (More)

Topic mentions per year

Topic mentions per year

1952-2017
010002000300019522016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
INTRODUCTION Carbon nanotubes (CNT) have recently been studied as novel and versatile drug and gene delivery vehicles. When CNT… (More)
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Review
2015
Review
2015
Chemotherapy-induced cardiotoxicity is a serious complication that poses a serious threat to life and limits the clinical use of… (More)
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Highly Cited
2008
Highly Cited
2008
Abnormal accumulation of myeloid-derived suppressor cells (MDSC) is an important mechanism of tumor immune evasion… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND We present the combined results of two trials that compared adjuvant chemotherapy with or without concurrent… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Doxorubicin is a highly effective and widely used cytotoxic agent with application that is limited by cardiotoxicity… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30… (More)
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Highly Cited
2000
Highly Cited
2000
Human breast tumours are diverse in their natural history and in their responsiveness to treatments. Variation in transcriptional… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE Gemcitabine plus cisplatin (GC) and methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) were compared in… (More)
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Highly Cited
1999
Highly Cited
1999
PURPOSE To assess patient and tumor characteristics associated with a complete pathologic response (pCR) in both the breast and… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To estimate the incidence of serious and fatal adverse drug reactions (ADR) in hospital patients. DATA SOURCES Four… (More)
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