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Decorin Protein Core Inhibits in Vivo Cancer Growth and Metabolism by Hindering Epidermal Growth Factor Receptor Function and Triggering Apoptosis via Caspase-3 Activation*
Decorin is not only a regulator of matrix assembly but also a key signaling molecule that modulates the activity of tyrosine kinase receptors such as the epidermal growth factor receptor (EGFR).Expand
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Molecular Determinants of Epidermal Growth Factor Binding: A Molecular Dynamics Study
The epidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinase family that plays a role in multiple cellular processes. Activation of EGFR requires binding of a ligand on theExpand
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Indium-LLL labeled platelets: studies on preparation and evaluation of in vitro and in vivo functions.
Abstract Platelets have been labeled with a lipid soluble complex of the radionuclide indium-111. The complex is formed with 8-hydroxyquinoline and extracted in chloroform which is then evaporated toExpand
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Dosimetry of iodine-131 ethiodol in the treatment of hepatoma.
The in vivo distribution and kinetics of [131I]Ethiodol injected through the hepatic artery have been measured on a group of four patients with hepatocellular carcinoma. The [131I]Ethiodol wasExpand
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Radiolabeled peptides in oncology: role in diagnosis and treatment.
There has been an exponential growth in the development of radiolabeled peptides for diagnostic and therapeutic applications in the last decade. The automated means of synthesizing these compounds inExpand
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Indium-111-labeled autologous leukocytes in man.
Autologous leukocytes have been isolated, labeled with indium-111, and administered to 15 patients suspected of inflammatory disease. The stability of the label has been demonstrated and the in vivoExpand
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Sentinel lymph nodes in a swine model with melanoma: contrast-enhanced lymphatic US.
PURPOSE To determine if lymphatic channels and sentinel lymph nodes (SLNs) with and without metastases can be detected with lymphatic ultrasonography (US) after peritumoral injection of a US contrastExpand
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Targeting Apoptosis for Optical Imaging of Infection
PurposeInfection is ubiquitous and a major cause of morbidity and mortality. The most reliable method for localizing infection requires radiolabeling autologous white blood cells ex vivo. A compoundExpand
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Indium-111-labeled cellular blood components: mechanism of labeling and intracellular location in human neutrophils.
Human neutrophils were labeled with In-111 oxine by incubation at room temperature, and the fate of the oxine and the intracellular location of the In-111 were determined. Neutral (1:3) In-111 oxineExpand
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The preparation of indium-111 labelled bleomycin for tumour localisation.
  • M. Thakur
  • Chemistry, Medicine
  • The International journal of applied radiation…
  • 1 June 1973
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