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A new crossover operator for real coded genetic algorithms
We define two new generational genetic algorithms LX–MPTM and LX–NUM to solve general nonlinear global optimization problem. Expand
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Safety and Immunogenicity of a Recombinant Tetravalent Dengue Vaccine in 9–16 Year Olds: A Randomized, Controlled, Phase II Trial in Latin America
Background: The dengue virus is a member of the Flavivirus (FV) genus, which also includes the yellow fever virus. Dengue disease is caused by any 1 of 4 dengue virus serotypes and is a seriousExpand
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Decorin Protein Core Inhibits in Vivo Cancer Growth and Metabolism by Hindering Epidermal Growth Factor Receptor Function and Triggering Apoptosis via Caspase-3 Activation*
Decorin is not only a regulator of matrix assembly but also a key signaling molecule that modulates the activity of tyrosine kinase receptors such as the epidermal growth factor receptor (EGFR).Expand
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Molecular Determinants of Epidermal Growth Factor Binding: A Molecular Dynamics Study
The epidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinase family that plays a role in multiple cellular processes. Activation of EGFR requires binding of a ligand on theExpand
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Radiolabeled peptides in oncology: role in diagnosis and treatment.
There has been an exponential growth in the development of radiolabeled peptides for diagnostic and therapeutic applications in the last decade. The automated means of synthesizing these compounds inExpand
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Targeting Apoptosis for Optical Imaging of Infection
PurposeInfection is ubiquitous and a major cause of morbidity and mortality. The most reliable method for localizing infection requires radiolabeling autologous white blood cells ex vivo. A compoundExpand
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An inventory of the chiropteran fauna of Himachal Pradesh, northwestern India with some ecological observations
A chiropteran inventory of Himachal Pradesh, northwestern India is presented. Based on field observation and the study of museum collections and published literature, the occurrence of 28 speciesExpand
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Indium-111-labeled cellular blood components: mechanism of labeling and intracellular location in human neutrophils.
Human neutrophils were labeled with In-111 oxine by incubation at room temperature, and the fate of the oxine and the intracellular location of the In-111 were determined. Neutral (1:3) In-111 oxineExpand
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An antimetastatic role for decorin in breast cancer.
Decorin, a member of the small leucine-rich proteoglycan gene family, down-regulates members of the ErbB receptor tyrosine kinase family and attenuates their signaling, leading to growth inhibition.Expand
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Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism.
BACKGROUND The antiangiogenic approach to controlling cancer requires a better understanding of angiogenesis and the discovery of new compounds that modulate this key biological process. Here weExpand
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