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Cyclophosphamide

Known as: CPM, 2H-1,3,2-oxazaphosphorin-2-amine, N,N-is(2-chloroethyl)tetrahydro-,2-oxide, N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide 
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active… 
National Institutes of Health

Related topics

Related topics

47 relations

Narrower (15)

4-methylcyclophosphamideACP protocolCEOP-B protocolCISCA protocol
CEV regimenCFP protocolCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristineCMF-B protocol

Papers overview

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Highly Cited
2011
Highly Cited
2011
Activation of carbodiimide and transformation with amine to guanidinate group by Ln(OAr)3(THF)2 (Ln: lanthanide and yttrium) and Ln(OAr)3(THF)2 as a novel precatalyst for addition of amines to…
Reaction of Ln(OAr(1))(3)(THF)(2) (Ar(1)= [2,6-((t)Bu)(2)-4-MeC(6)H(2)] with carbodiimides (RNCNR) in toluene afforded the RNCNR… 
Highly Cited
2001
Highly Cited
2001
Taxon sampling and the phylogenetic position of Passeriformes: evidence from 916 avian cytochrome b sequences.
Attempts to resolve relationships among major groups of birds from DNA sequences have been plagued by the problem of apparent… 
Highly Cited
2000
Highly Cited
2000
Comparison of chemotherapy to radiotherapy as consolidation of complete or good partial response after six cycles of chemotherapy for patients with advanced Hodgkin's disease: results of the groupe d…
The treatment of advanced Hodgkin's disease (HD) with chemotherapy (CTx) alone or combined modality treatments has been… 
Highly Cited
1990
Highly Cited
1990
Mutants of ubiquinol-cytochrome c2 oxidoreductase resistant to Qo site inhibitors: consequences for ubiquinone and ubiquinol affinity and catalysis.
Seven single-site mutants in six residues of the cyt b polypeptide of Rhodobacter capsulatus selected for resistance to the Qo… 
Highly Cited
1987
Highly Cited
1987
A single dose of endotoxin activates neutrophils without activating complement.
Both complement (C) and neutrophils (PMN) are activated in critically ill patients. To evaluate the role of endotoxin in this… 
Highly Cited
1986
Highly Cited
1986
Regulation of adenovirus gene expression in human WI38 cells by an E1B-encoded tumor antigen
Adenovirus mutants carrying alterations in the gene encoding the E1B 19-kilodalton tumor antigen (19K protein) cause enhanced… 
Highly Cited
1983
Highly Cited
1983
Marked reduction of DNA antibody production and glomerulopathy in thymulin (FTS-Zn) or cyclosporin A treated (NZB X NZW) F1 mice.
In this study we have evaluated the action of two compounds, cyclosporin A (Cy A) and thymulin (FTS-Zn) in old (NZB X NZW) F1… 
Highly Cited
1982
Highly Cited
1982
The in vitro teratogenicity of cyclophosphamide in rat embryos.
When Day 10 rat embryos were grown in culture containing cyclophosphamide, an hepatic microsomal fraction (S-9), and cofactors… 
Highly Cited
1966
Highly Cited
1966
Studies on relationships between structure and function of hemoglobin M-Iwate.
Abstract Functional properties of hemoglobin Miwate (α287 tyrβ2a) were studied with particular reference to their relations with… 
Highly Cited
1947
Highly Cited
1947
DISEASE
Background: Little is known about patients who frequently visit the emergency department (ED) for acute exacerbation of chronic…