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Cyclophosphamide

Known as: CPM, 2H-1,3,2-oxazaphosphorin-2-amine, N,N-is(2-chloroethyl)tetrahydro-,2-oxide, N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide 
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active… 
National Institutes of Health

Related topics

Related topics

47 relations

Narrower (15)

4-methylcyclophosphamideACP protocolCEOP-B protocolCISCA protocol
CEV regimenCFP protocolCHOP protocol-cyclophosphamide/doxorubicin/prednisone/vincristineCMF-B protocol

Papers overview

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Highly Cited
2011
Highly Cited
2011
Activation of carbodiimide and transformation with amine to guanidinate group by Ln(OAr)3(THF)2 (Ln: lanthanide and yttrium) and Ln(OAr)3(THF)2 as a novel precatalyst for addition of amines to…
Reaction of Ln(OAr(1))(3)(THF)(2) (Ar(1)= [2,6-((t)Bu)(2)-4-MeC(6)H(2)] with carbodiimides (RNCNR) in toluene afforded the RNCNR… 
Highly Cited
2001
Highly Cited
2001
Taxon sampling and the phylogenetic position of Passeriformes: evidence from 916 avian cytochrome b sequences.
Attempts to resolve relationships among major groups of birds from DNA sequences have been plagued by the problem of apparent… 
Highly Cited
2000
Highly Cited
2000
Comparison of chemotherapy to radiotherapy as consolidation of complete or good partial response after six cycles of chemotherapy for patients with advanced Hodgkin's disease: results of the groupe d…
The treatment of advanced Hodgkin's disease (HD) with chemotherapy (CTx) alone or combined modality treatments has been… 
Highly Cited
1998
Highly Cited
1998
Noncoherent sequence detection of continuous phase modulations
In this paper, noncoherent sequence detection (NSD) proposed Colavolpe and Raheli (see Proc. IEEE Int. Conf. Commun. (ICC '97… 
Highly Cited
1990
Highly Cited
1990
Mutants of ubiquinol-cytochrome c2 oxidoreductase resistant to Qo site inhibitors: consequences for ubiquinone and ubiquinol affinity and catalysis.
Seven single-site mutants in six residues of the cyt b polypeptide of Rhodobacter capsulatus selected for resistance to the Qo… 
Highly Cited
1987
Highly Cited
1987
A single dose of endotoxin activates neutrophils without activating complement.
Both complement (C) and neutrophils (PMN) are activated in critically ill patients. To evaluate the role of endotoxin in this… 
Highly Cited
1986
Highly Cited
1986
Glutathione depletion as a determinant of sensitivity of human leukemia cells to cyclophosphamide.
The role of glutathione (GSH) as a determinant of cellular sensitivity to the cytotoxic and DNA-damaging effects of… 
Highly Cited
1983
Highly Cited
1983
The T lymphocyte response to cytochrome c. IV. Distinguishable sites on a peptide antigen which affect antigenic strength and memory.
The murine T cell proliferative response to the carboxyl terminal cyanogen bromide cleavage fragment 81-104 of pigeon cytochrome… 
Highly Cited
1983
Highly Cited
1983
Marked reduction of DNA antibody production and glomerulopathy in thymulin (FTS-Zn) or cyclosporin A treated (NZB X NZW) F1 mice.
In this study we have evaluated the action of two compounds, cyclosporin A (Cy A) and thymulin (FTS-Zn) in old (NZB X NZW) F1… 
Highly Cited
1947
Highly Cited
1947
DISEASE
Background: Little is known about patients who frequently visit the emergency department (ED) for acute exacerbation of chronic… 
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