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Dactinomycin

Known as: 2-bis[Cyclo(N-methyl-L-valyl-sarcosyl-L-prolyl-D-valyl-L-threonyl)]-1,9 dimethyl-4,6 3H-phenoxazinone-3, AD, Actinomycin I1 
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA… 
National Institutes of Health

Related topics

Related topics

43 relations
AcFuCy protocolChoriocarcinomaEMA-CO RegimenIn Blood

Broader (1)

Antibiotics, Antineoplastic

Narrower (18)

BCD protocolCosmegenDD1 protocolFDV protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis.
Toxins convert the hepatocellular response to tumor necrosis factor-α (TNF-α) stimulation from proliferation to cell death… 
Highly Cited
1991
Highly Cited
1991
Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events.
The human hepatoma cell line, Hep3B, synthesizes large quantities of erythropoietin (Epo) mRNA and protein in a regulated manner… 
Highly Cited
1988
Highly Cited
1988
Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP.
Highly Cited
1986
Highly Cited
1986
Bovine adrenocortical cytochrome P-450(17 alpha). Regulation of gene expression by ACTH and elucidation of primary sequence.
In the steroidogenic pathway of the adrenal cortex, 17 alpha-hydroxylase cytochrome P-450 (P-450(17 alpha)) is a major regulatory… 
Highly Cited
1972
Highly Cited
1972
Binding of cadmium ions by rat liver and kidney.
Review
1966
Review
1966
Synchronous behavior pattern of key glycolytic enzymes: glucokinase, phosphofructokinase, and pyruvate kinase.
Highly Cited
1965
Highly Cited
1965
Stimulation of DNA synthesis by isoproterenol in the salivary gland.
Highly Cited
1964
Highly Cited
1964
MACROMOLECULE SYNTHESIS AND THE INFLUENCE OF ACTINOMYCIN ON EARLY DEVELOPMENT.
Highly Cited
1964
Highly Cited
1964
A PARADOXICAL EFFECT OF ACTINOMYCIN D: THE MECHANISM OF REGULATION OF ENZYME SYNTHESIS BY HYDROCORTISONE.
tions (,10-3 M) of pyruvate will induce prompt and sustained stimulation of sodium transport. Only pyruvate and, to a lesser… 
Highly Cited
1964
Highly Cited
1964
THE EFFECTS OF ACTINOMYCIN D AND PUROMYCIN ON MORPHOGENESIS IN AMPHIBIAN EGGS AND ACETABULARIA MEDITERRANEA.
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