Doxorubicin Hydrochloride

Known as: 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), Chloridrato de Doxorrubicina, L-Lyxo-hexopyranoside, 3b-glycol-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1a-naphthacenyl 3-amino-2,3,6-trideoxy-alpha-, hydrochloride 
The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
MYC rearrangements occur in 5% to 10% of diffuse large B-cell lymphomas (DLBCL) and confer an increased risk to cyclophosphamide… (More)
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Highly Cited
2012
Highly Cited
2012
TP53 mutation is an independent marker of poor prognosis in patients with diffuse large B-cell lymphoma (DLBCL) treated with… (More)
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Highly Cited
2012
Highly Cited
2012
Pharmacokinetics of 8 doses of rituximab (375 mg/m(2)) given in combination with 2-week cyclophosphamide, hydroxydaunorubicin… (More)
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Highly Cited
2007
Highly Cited
2007
DC Bead is a FDA cleared embolisation device for the treatment of hypervascular tumours and arteriovenous malformations. This… (More)
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Highly Cited
2006
Highly Cited
2006
This work is intended to develop and evaluate a new polymer–lipid hybrid nanoparticle system that can efficiently load and… (More)
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Highly Cited
2000
Highly Cited
2000
Lovastatin, a drug commonly used in the clinic to treat hypercholesterolemia, has previously been reported to exert antitumor… (More)
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Highly Cited
2000
Highly Cited
2000
The purpose of this study was to compare a maintenance-free chemotherapy protocol based on CHOP (H from hydroxydaunorubicin… (More)
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Highly Cited
1995
Highly Cited
1995
OBJECTIVE To improve current adjuvant results in patients with resectable mammary carcinoma and more than three positive axillary… (More)
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Highly Cited
1983
Highly Cited
1983
This investigation examined the effect of the anthracycline antitumor agents on reactive oxygen metabolism in rat heart. Oxygen… (More)
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1977
1977
Doxorubicin hydrochloride (Adriamycin) therapy was associated with renal failure in a 78-year-old man. The pathophysiologic… (More)
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