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Uncoupling Agents

Known as: Agents, Uncoupling 
Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those… Expand
National Institutes of Health

Related topics

Related topics

25 relations

Narrower (19)

2,4-Dinitrophenol4,6-dinitro-o-cresolAlamethicinAurovertins
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Broader (1)

Enzyme Inhibitors
In BloodOxidative Phosphorylationaspects of radiation effectschemical synthesis
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler.
Nonalcoholic fatty liver disease (NAFLD) affects one in three Americans and is a major predisposing condition for the metabolic… Expand
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Highly Cited
2001
Highly Cited
2001
How to close a gap junction channel. Efficacies and potencies of uncoupling agents.
 
Highly Cited
1992
Highly Cited
1992
Relative mitochondrial membrane potential and [Ca2+]i in type I cells isolated from the rabbit carotid body.
1. In the accompanying paper (Duchen & Biscoe, 1992) we have described graded changes in autofluorescence derived from… Expand
Highly Cited
1969
Highly Cited
1969
Mechanism of Action of Reagents that uncouple Oxidative Phosphorylation
Uncoupling agents may act by causing conformational transitions in mitochondrial catalytic proteins. 
Highly Cited
1969
Highly Cited
1969
Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria
THE existence of an electrical potential difference at the mitochondrial membrane is one of the postulates of Mitchell's… Expand
Highly Cited
1965
Highly Cited
1965
THE ENERGY-LINKED REACTION OF CALCIUM WITH MITOCHONDRIA.
  • B. Chance
  • The Journal of biological chemistry
  • 1965
    • Corpus ID: 32251768
The reaction of divalent cations with mitochondria has been a subject of investigation from various standpoints for over 10 years… Expand
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Highly Cited
1962
Highly Cited
1962
A new class of uncoupling agents--carbonyl cyanide phenylhydrazones.
 
Highly Cited
1962
Highly Cited
1962
Platelet aggregation
  • J. R. O'brien
  • Journal of clinical pathology
  • 1962
    • Corpus ID: 19112233
Platelets in native blood adhere spontaneously to glass independently of temperature: if adenosine diphosphate is added to the… Expand
Highly Cited
1960
Highly Cited
1960
Photophosphorylation by swiss-chard chloroplasts.
  • M. Avron
  • Biochimica et biophysica acta
  • 1960
    • Corpus ID: 37977864
Abstract 1. 1. The preparation of chloroplasts and chloroplast fragments from swiss-chard, which were active in… Expand
Highly Cited
1960
Highly Cited
1960
The nature and mechanism of action of uncoupling agents present in mitochrome preparations.
Abstract 1. 1. The uncoupling activity of mitochrome preparations was not affected by addition of Na2S2O4, K3Fe(CN)6, CO or IO… Expand
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