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Uncoupling Agents

Known as: Agents, Uncoupling 
Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those… Expand
National Institutes of Health

Related topics

Related topics

25 relations

Narrower (19)

2,4-Dinitrophenol4,6-dinitro-o-cresolAlamethicinAurovertins
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Broader (1)

Enzyme Inhibitors
In BloodOxidative Phosphorylationaspects of radiation effectschemical synthesis
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis
Damage to mitochondria often results in the activation of both mitophagy and mitochondrial apoptosis. The elimination of… Expand
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Highly Cited
2013
Highly Cited
2013
Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler.
Nonalcoholic fatty liver disease (NAFLD) affects one in three Americans and is a major predisposing condition for the metabolic… Expand
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2003
2003
Effects of heart isolation, voltage-sensitive dye, and electromechanical uncoupling agents on ventricular fibrillation.
We tested whether the interventions typically required for optical mapping affect activation patterns during ventricular… Expand
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Highly Cited
2001
Highly Cited
2001
How to close a gap junction channel. Efficacies and potencies of uncoupling agents.
 
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Highly Cited
1999
Highly Cited
1999
The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids.
Gonococci often infect mucosal surfaces bathed in antibacterial fatty acids (FAs). Resistance of gonococci to FAs and other… Expand
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Highly Cited
1997
Highly Cited
1997
Gap junctions equalize intracellular Na+ concentration in astrocytes.
Gap junctions between glial cells allow intercellular exchange of ions and small molecules. We have investigated the influence of… Expand
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Highly Cited
1992
Highly Cited
1992
Relative mitochondrial membrane potential and [Ca2+]i in type I cells isolated from the rabbit carotid body.
1. In the accompanying paper (Duchen & Biscoe, 1992) we have described graded changes in autofluorescence derived from… Expand
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Highly Cited
1969
Highly Cited
1969
Mechanism of Action of Reagents that uncouple Oxidative Phosphorylation
Uncoupling agents may act by causing conformational transitions in mitochondrial catalytic proteins. 
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Highly Cited
1969
Highly Cited
1969
Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria
THE existence of an electrical potential difference at the mitochondrial membrane is one of the postulates of Mitchell's… Expand
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Highly Cited
1965
Highly Cited
1965
THE ENERGY-LINKED REACTION OF CALCIUM WITH MITOCHONDRIA.
  • Britton Chance
  • The Journal of biological chemistry
  • 1965
    • Corpus ID: 32251768
An apparatus for communicating the inability of a coin change making mechanism to return correct change in which the availability… Expand
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