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Tyrosine Hydroxylase Inhibitor

Any substance that inhibits tyrosine 3-monooxygenase (tyrosine hydroxylase), an enzyme that catalyzes the conversion of tyrosine to… Expand
National Institutes of Health

Papers overview

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2005
2005
BACKGROUND The ability of animals to make morphine has been in question for the last 30 years. Studies have demonstrated that… Expand
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Highly Cited
2001
Highly Cited
2001
The plasmalemmal dopamine (DA) transporter (DAT) is a principal site of action for cocaine. This report presents the novel… Expand
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1998
1998
Alpha-methyl-p-tyrosine (alphaMPT), an inhibitor of tyrosine hydroxylase, was administered to mice to block noradrenaline… Expand
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Highly Cited
1997
Highly Cited
1997
The impact of endogenous dopamine on in vivo measurement of D2 receptors in humans was evaluated with single photon emission… Expand
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Highly Cited
1996
Highly Cited
1996
The immune and the nervous systems are anatomically closely related and interact with each other by molecules common to both… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Most hypotheses of the therapeutic mechanism of action of antidepressant drugs have focused on the role of the… Expand
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Highly Cited
1985
Highly Cited
1985
Fast cyclic voltammetry was used to monitor the release of electroactive material in the striatum following electrical… Expand
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1985
1985
Mongolian gerbils were treated with alpha-methyl-para-tyrosine methyl ester (AMPT, a tyrosine hydroxylase inhibitor), in order to… Expand
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Highly Cited
1972
Highly Cited
1972
SummaryDOPA and 5-HTP accumulated in vivo in rat brain after decarboxylase inhibition with NSD 1015 (3-hydroxybenzylhydrazine… Expand
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Highly Cited
1972
Highly Cited
1972
Small doses of ethanol (1 or 2 g/kg 20% w/v) caused increased motor activity in rats and mice as measured by an Animex activity… Expand
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