Tyrosine Hydroxylase Inhibitor

Any substance that inhibits tyrosine 3-monooxygenase (tyrosine hydroxylase), an enzyme that catalyzes the conversion of tyrosine to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2016
051019672016

Papers overview

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2006
2006
The specific mechanisms underlying (+)-3,4-methylenedioxymethamphetamine (MDMA)-induced damage to 5-HT terminals are unknown… (More)
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2005
2005
BACKGROUND The ability of animals to make morphine has been in question for the last 30 years. Studies have demonstrated that… (More)
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1998
1998
Alpha-methyl-p-tyrosine (alphaMPT), an inhibitor of tyrosine hydroxylase, was administered to mice to block noradrenaline… (More)
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Highly Cited
1997
Highly Cited
1997
The impact of endogenous dopamine on in vivo measurement of D2 receptors in humans was evaluated with single photon emission… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Most hypotheses of the therapeutic mechanism of action of antidepressant drugs have focused on the role of the… (More)
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1996
1996
Planarians (Dugesia dorotocephala) were evaluated as bioassay organisms to detect inhibition of tyrosine hydroxylase, the rate… (More)
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1990
1990
Depletion of brain dopamine (DA) by pretreatment with the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine (AMT) has been… (More)
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1985
1985
Mongolian gerbils were treated with alpha-methyl-para-tyrosine methyl ester (AMPT, a tyrosine hydroxylase inhibitor), in order to… (More)
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Highly Cited
1972
Highly Cited
1972
DOPA and 5-HTP accumulated in vivo in rat brain after decarboxylase inhibition with NSD 1015 (3-hydroxybenzylhydrazine). This… (More)
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Highly Cited
1972
Highly Cited
1972
Small doses of ethanol (1 or 2 g/kg 20% w/v) caused increased motor activity in rats and mice as measured by an Animex activity… (More)
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