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Tumor Suppressor Genes

Known as: Antioncogene, Emerogenes, Genes, Cancer Suppressor 
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor… 
National Institutes of Health

Related topics

Related topics

49 relations
ANP32D proteinAbsent in melanoma 1 proteinBCSC-1 ProteinBRCA3 Protein

Narrower (7)

CDK2AP2 protein, humanPERP protein, humanPlagl1 protein, mouseRetinoblastoma Genes

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Long non-coding RNA CASC 2 suppresses the proliferation of gastric cancer cells by regulating the MAPK signaling pathway
Long non-coding RNAs (lncRNAs) have been shown to play important roles in tumorigenesis. However, the biological functions and… 
Review
2014
Review
2014
Association of Chromosomal Translocation and MiRNA Expression with The Pathogenesis of Multiple Myeloma
Multiple myeloma (MM), is the second most common blood cancer after non-Hodgkin’s lymphoma. Genetic changes, structural and… 
2002
2002
Cell Cycle Arrest and Repression of Cyclin D 1 Transcription by INI 1 / hSNF 5
Cell Cycle Arrest and Repression of Cyclin D1 Transcription by INI1/hSNF5 Zhi-Kai Zhang, Kelvin P. Davies, Jeffrey Allen, Liang… 
2000
2000
Angiogenesis and the multistage development of lung cancers.
As with other epithelial tumors, lung cancers develop after a series of morphological and molecular changes. The molecular… 
1998
1998
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions.
Programmed cell death (PCD), also known as apoptosis, is a genetically controlled cellular response, manifested in… 
1997
1997
Tolerance to p 53 by A 2 . 1-restricted Cytotoxic T Lymphocytes
Elevated levels of the p53 protein occur in , 50% of human malignancies, which makes it an excellent target for a broad-spectrum… 
1996
1996
Loss of heterozygosity of multiple tumor suppressor genes in human gastric cancers by polymerase chain reaction.
Loss of heterozygosity (LOH) occurring on various chromosomes has been described in the majority of human tumors and its targets… 
Highly Cited
1996
Highly Cited
1996
Physical mapping of chromosome 8p22 markers and their homozygous deletion in a metastatic prostate cancer.
Numerous studies have implicated the short arm of chromosome 8 as the site of one or more tumor suppressor genes inactivated in… 
1994
1994
Retinoblastoma antioncogene is involved in the inhibition of myogenesis by polyomavirus large T antigen.
The expression of polyomavirus large T antigen in stably transfected C2 myoblast cells inhibits terminal differentiation without… 
Highly Cited
1986
Highly Cited
1986
Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13.
The study of recessive oncogenes such as those responsible for retinoblastoma and Wilms tumor is difficult because the gene…