Tumor Suppressor Genes

Known as: Antioncogene, Emerogenes, Genes, Cancer Suppressor 
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Lung cancer is the leading cause of cancer deaths worldwide, yet there remains a lack of specific and sensitive tools for early… (More)
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Review
2017
Review
2017
The tumor suppressor p53 functions primarily as a transcription factor. Mutation of the TP53 gene alters its response pathway… (More)
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Review
2016
Review
2016
MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of gene expression. Compelling evidences… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs that target protein-coding mRNAs at the post… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND AND AIMS microRNAs (miRNAs) are short noncoding RNAs that regulate gene expression negatively. Although a role for… (More)
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Highly Cited
2006
Highly Cited
2006
Small noncoding microRNAs (miRNAs) can contribute to cancer development and progression and are differentially expressed in… (More)
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Highly Cited
2005
Highly Cited
2005
n engl j med 353;17 www.nejm.org october 27, 2005 1768 in such a way as to ensure reasonably even coverage of the whole genome… (More)
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Highly Cited
2003
Highly Cited
2003
The biochemical properties of beclin 1 suggest a role in two fundamentally important cell biological pathways: autophagy and… (More)
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Highly Cited
1996
Highly Cited
1996
About 90 percent of human pancreatic carcinomas show allelic loss at chromosome 18q. To identify candidate tumor suppressor genes… (More)
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Highly Cited
1993
Highly Cited
1993
The ability of p53 to activate transcription from specific sequences suggests that genes induced by p53 may mediate its… (More)
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