Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor.

@article{Wood2003SmallUM,
  title={Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor.},
  author={Lauren D. Wood and Brenda J. Irvin and Giuseppina Nucifora and Karanina Luce and Scott W. Hiebert},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2003},
  volume={100 6},
  pages={3257-62}
}
Posttranslational modification by small ubiquitin-like modifier (SUMO) conjugation regulates the subnuclear localization of several proteins; however, SUMO modification has not been directly linked to nuclear export. The ETS (E-Twenty-Six) family member TEL (ETV6) is a transcriptional repressor that can inhibit Ras-dependent colony growth in soft agar and… CONTINUE READING