Retinoblastoma Genes

Known as: Rb Gene, Gene, Rb, Genes, Retinoblastoma 
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging… (More)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Most personalized cancer care strategies involving DNA sequencing are highly reliant on acquiring sufficient fresh or… (More)
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Highly Cited
2004
Highly Cited
2004
The retinoblastoma gene family consists of three genes: RB, p107, and p130. While loss of pRB causes retinoblastoma in humans and… (More)
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Highly Cited
1997
Highly Cited
1997
The retinoblastoma gene family consists of the tumor suppressor protein pRB and its two relatives p107 and p130. These proteins… (More)
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Highly Cited
1991
Highly Cited
1991
Inactivation of the retinoblastoma gene appears to have a fundamental role in the genesis of retinoblastoma, osteosarcoma, and… (More)
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Highly Cited
1991
Highly Cited
1991
Human cervical carcinoma cell lines that were either positive or negative for human papillomavirus (HPV) DNA sequences were… (More)
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1991
1991
THE transcription of a eukaryotic gene is a consequence of intricate interactions between members of a set of transcription… (More)
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Highly Cited
1991
Highly Cited
1991
THE retinoblastoma gene (Rb) product is a negative regulator of cellular proliferation1, an effect that could be mediated in part… (More)
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Highly Cited
1990
Highly Cited
1990
Mutational inactivation of the retinoblastoma gene (RB) is found in all retinoblastomas and in a subset of other human neoplasms… (More)
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Highly Cited
1989
Highly Cited
1989
RETINOBLASTOMA and osteosarcoma arise from cells that have lost both functional copies of the retinoblastoma gene1–3. Using the… (More)
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Review
1984
Review
1984
The retinoblastoma gene can be considered a model for a class of recessive human cancer genes that have a "suppressor" or… (More)
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