Toll-like receptors

Known as: Toll Like Receptor, Toll-Like Receptors [Chemical/Ingredient], like receptors toll 
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the… (More)

Topic mentions per year

Topic mentions per year

1955-2018
0500100019552017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Toll-like receptors (TLRs) play a crucial role in host defense against microbial infection. The microbial ligands recognized by… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Viral infection of mammalian host results in the activation of innate immune responses. Toll-like receptors (TLRs) have been… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Stimulation of Toll-like receptors (TLRs) triggers activation of a common MyD88-dependent signaling pathway as well as a MyD88… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Autoreactive B cells are present in the lymphoid tissues of healthy individuals, but typically remain quiescent. When this… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Toll-like receptors (TLRs) are a family of innate immune-recognition receptors that recognize molecular patterns associated with… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, but… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Toll-like receptors (TLRs) are ancient microbial pattern recognition receptors highly conserved from Drosophila to humans. To… (More)
  • table I
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Toll-like receptors (TLRs) have been shown to participate in the recognition of pathogens by the innate immune system, but it is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The generation of cell-mediated immunity against many infectious pathogens involves the production of interleukin-12 (IL-12), a… (More)
  • figure 2
  • figure 1
  • figure 4
  • figure 3
Is this relevant?