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TLR7 protein, human

Known as: Toll-Like Receptor 7-Like, toll-like receptor 7, human, hTLR7 
Toll-like receptor 7 (1049 aa, ~121 kDa) is encoded by the human TLR7 gene. This protein plays a role in the response to single-stranded RNA.
National Institutes of Health

Related topics

Related topics

22 relations
852AAntiviral ResponseDendritic Cell PathwayImmune response

Broader (2)

Toll-Like Receptor 7Toll-like receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Self-Assembled Ligands Targeting TLR7: A Molecular Level Investigation.
Toll-like receptors (TLRs) are pattern recognition transmembrane proteins that play an important role in innate immunity. In… 
2016
2016
Activation inhibitor for toll-like receptor 7 or toll-like receptor 9
In the present invention, a compound selected from cyclobakuchiol A, cyclobakuchiol B and derivatives thereof, a… 
2015
2015
Facile syntheses of functionalized toll-like receptor 7 agonists.
2015
2015
Mutational analysis identifies leucine-rich repeat insertions crucial for pigeon toll-like receptor 7 recognition and signaling.
2015
2015
Clearance of folliculotropic and tumor mycosis fungoides with topical 5% imiquimod
2014
2014
Homology and Molecular Dynamics Models of Toll‐Like Receptor 7 Protein and Its Dimerization
Toll‐like receptor protein 7 is a transmembrane protein playing a crucial role in the signaling pathways involved in innate… 
2011
2011
A protective role for toll-like receptor 3 but not toll-like receptor 7 in intimal hyperplasia
Highly Cited
2010
Highly Cited
2010
Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept.
Systemic administration of a Toll-like receptor 7 (TLR7) agonist is effective to in suppressing Th2 derived inflammation, however… 
2009
2009
Synthetic toll-like receptor 7 agonist as a conjugated adjuvant enhances the Th 1 type immunogenicity of influenza virus vaccine
Vaccination, one of the most effective and cost-efficient strategy in preventing and controlling influenza virus infection, also… 
2004
2004
Isatoribine, a toll-like receptor 7 agonist, significantly reduced plasma viral load in a clinical proof-of-concept study in patients with chronic hepatitis C virus infection.
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