Tocainide

Known as: Propanamide, 2-amino-N-(2,6-dimethylphenyl)-, Alanyl-2,6-xylidide, Tocainide [Chemical/Ingredient] 
An antiarrhythmic agent which exerts a potential- and frequency-dependent block of SODIUM CHANNELS.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
010203019762017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1990
1990
The inactivation of the sodium channels in human medulloblastoma cells was investigated with the whole-cell recording technique… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
1989
1989
The effects of intravenously administered subanesthetic concentrations of lidocaine, tocainide, and mexiletine on spontaneously… (More)
Is this relevant?
1987
1987
Tocainide is a derivative of lidocaine with anti-arrhythmic action and, unlike lidocaine, can be used for oral treatment… (More)
Is this relevant?
1982
1982
Tocainide, an oral form of lidocaine, was employed in 120 patients with recurrent malignant ventricular arrhythmia refractory to… (More)
Is this relevant?
1980
1980
The antimyotonic effect of the antiarrhythmic drug tocainide was tested in 14 patients. With 1200 to 1600 mg/d all patients… (More)
  • table 1
  • table 2
Is this relevant?
1980
1980
Effects of lidocaine and tocainide on transmembrane potentials were studied in isolated guineapig papillary muscles, superfused… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1978
1978
The electrophysiologic properties of tocainide were evaluated by electrophysiologic studies in 11 patients before, during and… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
1978
1978
Long-term tocainide therapy has been evaluated in 17 patients with ventricular arrhythmias. Ventricular tachycardia and/or… (More)
  • table 1
  • table 2
  • table 4
  • figure 1
  • figure 2
Is this relevant?
1977
1977
In a previous clinical study we demonstrated that tocainide is effective in the suppression of ventricular ectopic… (More)
Is this relevant?
1976
1976
Tocainide, a primary amine analogue of lidocaine, is effective against some experimental and clinical arrhythmias. Its… (More)
Is this relevant?