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Voltage-Gated Sodium Channel Blockers

Known as: Voltage-Gated Sodium Channel Inhibitors, Channel Blockers, Voltage Gated Sodium, Channel Blockers, Voltage-Gated Sodium 
A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.
National Institutes of Health

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AjmalineAprindineDisopyramideEncainide
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Manifestations in the Oral Mucosa of Erythromelalgia. A Case Report
Erythromelalgia or erythermalgia, is a peripheral paroxysmal vascular disease of the distal extremities, although it can also… 
2018
2018
Role of voltage-gated sodium channel blockers in the treatment of chronic pain: Potential uses in clinical practice based on available evidence.
2016
2016
Synthesis and characterization of novel conjugates of 4-[3-(aryl/heteroaryl)-3-oxo-propenyl]-benzaldehyde with thiazole and thiazolidinones as possible voltage-gated sodium channel blockers
A series of chalcones of thiazole and thiazolidinone (3a–3j) were synthesized, characterized and evaluated for anticonvulsant… 
2014
2014
[Progress in sodium channelopathies and biological functions of voltage-gated sodium channel blockers].
Voltage-gated sodium channels (VGSCs), which are widely distributed in the excitable cells, are the primary mediators of… 
2014
2014
Discovery of voltage-gated sodium channel inhibitors from tarantula venoms
Review
2010
Review
2010
Structural trends among second-generation voltage-gated sodium channel blockers.
2009
2009
Discovery of isoxazole voltage gated sodium channel blockers for treatment of chronic pain.
2006
2006
Pharmacological characterisation of sodium channels in sinoatrial node pacemaking in the rat heart.
1994
1994
Analysis of voltage-gated and synaptic conductances contributing to network excitability defects in the mutant mouse tottering.
1. Intracellular current- and voltage-clamp recordings were carried out in CA3 pyramidal neurons from hippocampal slices of adult… 
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