Voltage-Gated Sodium Channel Blockers

Known as: Voltage-Gated Sodium Channel Inhibitors, Channel Blockers, Voltage Gated Sodium, Channel Blockers, Voltage-Gated Sodium 
A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
012319942018

Papers overview

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2016
2016
A series of chalcones of thiazole and thiazolidinone (3a–3j) were synthesized, characterized and evaluated for anticonvulsant… (More)
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Review
2015
Review
2015
Voltage-gated sodium channels play a key role in the transmission of sensory information about the status of organs in the… (More)
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2014
2014
Voltage-gated sodium channels (VGSCs), which are widely distributed in the excitable cells, are the primary mediators of… (More)
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2012
2012
Recent findings showing a relation between mutations in the Na(V)1.7 channel in humans and altered pain sensation has contributed… (More)
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2011
2011
Blocking of certain sodium channels is considered to be an attractive mechanism to treat chronic pain conditions. Phenyl… (More)
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2011
2011
Hermitamides A and B are lipopeptides isolated from a Papau New Guinea collection of the marine cyanobacterium Lyngbya majuscula… (More)
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2009
2009
Neuronal sodium channels blockers interfere with ion flux and have been used for managing neuropathic pain, epilepsy, and… (More)
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2009
2009
Analogs of the previously reported voltage gated sodium channel blocker CDA54 were prepared in which one of the amide functions… (More)
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2009
2009
A series of novel isoxazole voltage gated sodium channel blockers have been synthesized and evaluated. Substitutions on the… (More)
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1994
1994
1. Intracellular current- and voltage-clamp recordings were carried out in CA3 pyramidal neurons from hippocampal slices of adult… (More)
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