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Disopyramide

Known as: Disopyramidum, Disopiramida, Disopyramide [Chemical/Ingredient] 
A class IA anti-arrhythmic agent with cardiac depressant property. Disopyramide blocks the fast sodium channel in normal cardiac cell membranes… 
National Institutes of Health

Related topics

Related topics

31 relations

Broader (3)

Anti-Arrhythmia AgentsPyridinesVoltage-Gated Sodium Channel Blockers
Atrial FibrillationAtrial FlutterAtrial Premature ComplexesDisopyramide Phosphate

Narrower (6)

Disopyramide 150 MG Oral CapsuleNorpacePalpitinRhythmodan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Repolarization Abnormality in Idiopathic Ventricular Fibrillation:
Introduction: We evaluated the characteristics of QT‐RR and QaT (apex of T wave)‐RR relationships in patients with idiopathic… 
1990
1990
Two types of sodium channel block by class-I antiarrhythmic drugs studied by using Vmax of action potential in single ventricular myocytes.
Highly Cited
1987
Highly Cited
1987
Diseases and drugs causing prolongation of the QT interval.
Highly Cited
1983
Highly Cited
1983
Resting and Rate‐Dependent Depression of Maximum Rate of Depolarisation (Vmax) in Guinea Pig Ventricular Action Potentials by Mexiletine, Disopyramide, and Encainide
The influence of stimulation rate on the ability of mexiletine, disopyramide. and encainide to depress the maximum rate of… 
Highly Cited
1982
Highly Cited
1982
Prediction of response to class I antiarrhythmic drugs during electrophysiologic study of ventricular tachycardia.
Highly Cited
1980
Highly Cited
1980
Quantitative analysis of the disopyramide concentration-effect relationship.
1. A combined pharmacokinetic-pharmacodynamic model has been used to analyse the relationship between QT prolongation and changes… 
Highly Cited
1980
Highly Cited
1980
Tocainide for drug-resistant ventricular arrhythmias: efficacy, side effects, and lidocaine responsiveness for predicting tocainide success.
Highly Cited
1978
Highly Cited
1978
Liquid chromatography in the monitoring of plasma levels of antiarrhythmic drugs.
Review
1978
Review
1978
Pharmacokinetics of antiarrhythmic drugs.
Highly Cited
1977
Highly Cited
1977
Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods.
Disopyramide has been shown in conditions of cholinergic blockade to have a depressant effect upon sinus node automaticity and… 
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