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Disopyramide Phosphate

Known as: alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide Phosphate(1:1), Disopyramide Phosphate (1:1), Disopyramide Phosphate [Chemical/Ingredient] 
A class Ia antiarrhythmic agent with cardiac depressant properties. Disopyramide phosphate exerts its actions by blocking both sodium and potassium… 
National Institutes of Health

Related topics

Related topics

15 relations
Anti-Arrhythmia AgentsAtrial FibrillationAtrial FlutterAtrial Premature Complexes

Narrower (3)

NorpacePalpitinRythmodan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Hemodynamic and electrocardiographic effects of disopyramide in patients with ventricular arrhythmia.
Antiarrhythmic and hemodynamic effects of i.v. disopyramide phosphate (1.7 mg/kg b.wt. over 2 min) have been studied in nine… 
1983
1983
The Direct Electrophysiologic Effects of Disopyramide Phosphate in the Transplanted Human Heart
To evaluate the direct electrophysiologic effects of i.v. disopyramide phosphate and to differentiate these effects from its… 
1980
1980
Pharmacokinetics of oral disopyramide phosphate in patients with renal impairment.
1 The pharmacokinetics of disopyramide were studied after the oral administration of a 300 mg dose to 11 patients with stable… 
1980
1980
Disopyramide-induced ventricular tachycardia.
A patient with ischemic cardiomyopathy and congestive heart failure was treated with disopyramide phosphate for ventricular… 
1979
1979
Cardiogenic shock and disopyramide phosphate.
DISOPYRAMIDE phosphate (Norpace) is a recently available antiarrhythmic drug. Although it has electrophysiologic properties… 
1979
1979
The effect of intravenous disopyramide phosphate on recurrent paroxysmal tachycardias.
1 Reccurent paroxysmal atrial, atrioventricular and ventricular tachycardias in 50 patients without acute coronary insufficiency… 
1978
1978
Disopyramide phosphate: is it just another quinidine.
We compared the effects of a therapeutic concentration of disopyramide with those of quinidine and lidocaine on the action… 
1978
1978
The electrophysiological effects of disopyramide phosphate on canine ventricular muscle and Purkinje fibers in normal and low potassium.
We studied the effect of lowering the extracellular potassium concentration ([K+]o) on the electrophysiological actions of… 
1977
1977
Disopyramide phosphate: tissue uptake and relationship between drug concentrations in the plasma and myocardium of rats.
Tissue uptake of total-14C and disopyramide (DP) was examined in rats following 5 to 100 mg/kg doses of [14C]-disopyramide… 
1974
1974
Comparative binding of disopyramide phosphate and quinidine sulfate to human plasma proteins.
Abstract Disopyramide phosphate and quinidine sulfate are pharmacologically related, but chemically unrelated, antiarrhythmic… 
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