Aprindine

ATP-sensitive K+ channels (K(ATP):SUR2A+Kir6.2) play a pivotal role in cardiac protection against ischemia and reperfusion injury… (More)

The risk of agranulocytosis associated with anti-arrhythmic drugs has been assessed by studying previous drug exposure of all… (More)

Antiarrhythmic effects of aprindine were examined using three canine ventricular arrhythmia models (induced by digitalis… (More)

Five cases of aprindine-induced polymorphous ventricular tachycardia (torsade de pointes) are presented. In four cases… (More)

Antiarrhythmic drugs may aggravate or even induce ventricular arrhythmias. This type of adverse reaction is becoming more… (More)

Little information exists regarding the effects of coronary artery occlusion on the distribution and actions of antiarrhythmic… (More)

Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic-toxic ratio. It has been used successfully in… (More)

The effects of various drugs on delayed activation of the ischemic myocardium and the incidence of ventricular arrhythmias were… (More)

Digitalis-induced OAP provide a mechanism of automaticity that may be responsible for many arrhythmias induced by cardiac… (More)

Twenty-three patients with recurrent ventricular tachycardia or ventricular fibrillation, or both, were treated with aprindine, a… (More)