Aprindine

Known as: Aprindina, Aprindinum, 1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl- 
A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
National Institutes of Health

Papers overview

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2005
2005
ATP-sensitive K+ channels (K(ATP):SUR2A+Kir6.2) play a pivotal role in cardiac protection against ischemia and reperfusion injury… (More)
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Review
1991
Review
1991
The risk of agranulocytosis associated with anti-arrhythmic drugs has been assessed by studying previous drug exposure of all… (More)
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1984
1984
Antiarrhythmic effects of aprindine were examined using three canine ventricular arrhythmia models (induced by digitalis… (More)
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1982
1982
Five cases of aprindine-induced polymorphous ventricular tachycardia (torsade de pointes) are presented. In four cases… (More)
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Highly Cited
1982
Highly Cited
1982
Antiarrhythmic drugs may aggravate or even induce ventricular arrhythmias. This type of adverse reaction is becoming more… (More)
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1981
1981
Little information exists regarding the effects of coronary artery occlusion on the distribution and actions of antiarrhythmic… (More)
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Review
1980
Review
1980
Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic-toxic ratio. It has been used successfully in… (More)
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Highly Cited
1977
Highly Cited
1977
The effects of various drugs on delayed activation of the ischemic myocardium and the incidence of ventricular arrhythmias were… (More)
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Highly Cited
1977
Highly Cited
1977
Digitalis-induced OAP provide a mechanism of automaticity that may be responsible for many arrhythmias induced by cardiac… (More)
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1977
1977
Twenty-three patients with recurrent ventricular tachycardia or ventricular fibrillation, or both, were treated with aprindine, a… (More)
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