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Aprindine

Known as: Aprindina, Aprindinum, 1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl- 
A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (4)

AmidonalFiborandesethylaprindinemoxaprindine

Broader (2)

Anti-Arrhythmia AgentsVoltage-Gated Sodium Channel Blockers
Aprindine hydrochlorideIn Bloodagonistsanalogs & derivatives
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1991
1991
High-performance liquid chromatographic method for the determination of nefazodone and its metabolites in human plasma using laboratory robotics.
1990
1990
Two types of sodium channel block by class-I antiarrhythmic drugs studied by using Vmax of action potential in single ventricular myocytes.
Highly Cited
1987
Highly Cited
1987
Block of activated and inactivated sodium channels by class-I antiarrhythmic drugs studied by using the maximum upstroke velocity (Vmax) of action potential in guinea-pig cardiac muscles.
Highly Cited
1982
Highly Cited
1982
Aggravation and Provocation of Ventricular Arrhythmias by Antiarrhythmic Drugs
Antiarrhythmic drugs may aggravate or even induce ventricular arrhythmias. This type of adverse reaction is becoming more… 
  • table 1
  • table 2
  • table 3
  • figure 2
  • table 4
Highly Cited
1982
Highly Cited
1982
Electrophysiologic drug testing in prophylaxis of sporadic paroxysmal atrial fibrillation: technique, application, and efficacy in severely symptomatic preexcitation patients.
Highly Cited
1981
Highly Cited
1981
Alterations in regional myocardial distribution and arrhythmogenic effects of aprindine produced by coronary artery occlusion in the dog.
Little information exists regarding the effects of coronary artery occlusion on the distribution and actions of antiarrhythmic… 
Review
1978
Review
1978
New antiarrhythmic agents: amiodarone, aprindine, disopyramide, ethmozin, mexiletine, tocainide, verapamil.
The present status, clinical experience, side effects, clinical pharmacology and electrophysiologic actions of seven new… 
Highly Cited
1977
Highly Cited
1977
Digitalis arrhythmias: role of oscillatory afterpotentials.
  • G. Ferrier
  • Progress in cardiovascular diseases
  • 1977
  • Corpus ID: 11133441
Highly Cited
1977
Highly Cited
1977
Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs.
1977
1977
Quality of the ideal antiarrhythmic drug.
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