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Aprindine
Known as:
Aprindina
, Aprindinum
, 1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-
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A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
National Institutes of Health
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Related topics
Related topics
14 relations
Narrower (4)
Amidonal
Fiboran
desethylaprindine
moxaprindine
Broader (2)
Anti-Arrhythmia Agents
Voltage-Gated Sodium Channel Blockers
Aprindine hydrochloride
In Blood
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Studies on the bradycardia induced by aprindine in rabbit sinoatrial node cells.
H. Kotake
,
O. Igawa
,
J. Miyamoto
,
J. Hasegawa
,
T. Furuse
,
H. Mashiba
Pharmacology
1986
Corpus ID: 46867485
The effects of aprindine (1 X 10(-7) to 4 X 10(-6) M) were examined on membrane potential and current of rabbit sinoatrial node…
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1983
1983
Aprindine Inhibits Calmodulin‐Stimulated Phosphodiesterase and Ca‐ATPase Activities
S. Levine
,
B. Hollier
Journal of Cardiovascular Pharmacology
1983
Corpus ID: 31955565
Summary Aprindine, an antiarrhythmic agent with structural similarities to lidocaine and procainamide, has proved effective in…
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1982
1982
Unusual electrophysiologic effects of aprindine.
W. Southworth
,
R. Ruffy
Chest
1982
Corpus ID: 5170888
We present a patient in whom administration of aprindine on two occasions was responsible for clinically significant sinus node…
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1980
1980
Pirmenol Hydrochloride (CI‐845): Antiarrhythmic Profile in Coronary Artery Ligated Conscious Dogs
T. E. Mertz
,
T. Steffe
Journal of Cardiovascular Pharmacology
1980
Corpus ID: 22205956
The antiarrhythmic profile of CI-845 (pirmenol hydrochloride) was assessed in conscious, coronary artery ligated dogs. In single…
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1980
1980
Serial electrophysiological testing of antiarrhythmic drug efficacy in patients with recurrent ventricular tachycardia.
G. Breithardt
,
L. Seipel
,
R. Abendroth
,
F. Loogen
European Heart Journal
1980
Corpus ID: 34523794
The purpose of the present study was to determine the predictive value of serial electrophysiological testing during…
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1977
1977
Effects of disopyramide and aprindine on arrhythmias after acute myocardial infarction.
H. Pouleur
,
J. Chaudron
,
P. Reyns
European journal of cardiology
1977
Corpus ID: 46584180
The incidence of ventricular arrhythmias after myocardial infarction was compared in a double blind study of disopyramide (33…
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1976
1976
Suppression of Ouabain‐induced Ventricular Rhythms with Aprindine HCl: A Comparison with Other Antiarrhythmic Agents
P. Foster
,
R. M. King
,
A. Nicoll
,
D. Zipes
Circulation
1976
Corpus ID: 11327342
Three groups of dogs were given ouabain (mean 60, μg/kg) until an accelerated ventricular escape (AVE) and repetitive ventricular…
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1976
1976
GLC determination of aprindine: quantitation and stability measurement.
B. Rutherford
,
R. Bishara
Journal of Pharmacy and Science
1976
Corpus ID: 45794590
A GLC method of analysis of a new antiarrhythmic agent, aprindine, is described. The raw material of the new drug substance…
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1975
1975
Cardiovascular effects of aprindine, a new antiarrhythmic drug.
Remme Wj
,
Verdouw Pd
1975
Corpus ID: 76845041
: The effects of aprinidine (AC 1802), a new antiarrhythmic drug, were studied in 9 anesthetized pigs. Aprindine was administered…
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1973
1973
Aprindine (AC 1802), a new anti-arrhythmic drug.
H. Kesteloot
,
W. van Mieghem
,
H. De Geest
Acta Cardiologica
1973
Corpus ID: 45364279
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