Aprindine

Known as: Aprindina, Aprindinum, 1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-

A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.

National Institutes of Health

Papers overview

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2009

The binding of the potent, basic antiarrhythmic agent aprindine to serum proteins was studied in solutions of human serum albumin…

1986

The effects of aprindine (1 X 10(-7) to 4 X 10(-6) M) were examined on membrane potential and current of rabbit sinoatrial node…

1983

Summary Aprindine, an antiarrhythmic agent with structural similarities to lidocaine and procainamide, has proved effective in…

1982

We present a patient in whom administration of aprindine on two occasions was responsible for clinically significant sinus node…

1980

The purpose of the present study was to determine the predictive value of serial electrophysiological testing during…

1977

The incidence of ventricular arrhythmias after myocardial infarction was compared in a double blind study of disopyramide (33…

1976

Three groups of dogs were given ouabain (mean 60, μg/kg) until an accelerated ventricular escape (AVE) and repetitive ventricular…

1976

A GLC method of analysis of a new antiarrhythmic agent, aprindine, is described. The raw material of the new drug substance…

1975

: The effects of aprinidine (AC 1802), a new antiarrhythmic drug, were studied in 9 anesthetized pigs. Aprindine was administered…

1973