Skip to search formSkip to main contentSkip to account menu

Aprindine

Known as: Aprindina, Aprindinum, 1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl- 
A class Ib anti-arrhythmia agent used to manage ventricular and supraventricular arrhythmias.
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (4)

AmidonalFiborandesethylaprindinemoxaprindine

Broader (2)

Anti-Arrhythmia AgentsVoltage-Gated Sodium Channel Blockers
Aprindine hydrochlorideIn Bloodagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Maintenance of sinus rhythm and recovery of atrial mechanical function after cardioversion with bepridil or in combination with aprindine in long-lasting persistent atrial fibrillation.
BACKGROUND The aim of this study was to evaluate pharmacological cardioversion of long-lasting persistent atrial fibrillation (AF… 
1993
1993
The metabolism of aprindine in relation to the sparteine/debrisoquine polymorphism.
1. Incubation of the class I antiarrhythmic drug aprindine (AP) with human liver microsomes resulted in the formation of two… 
1992
1992
Inhibition of human leukocyte elastase by N-substituted peptides containing alpha,alpha-difluorostatone residues at P1.
A series of tripeptides which contain alpha,alpha-difluorostatone residues at P1-P1' and span the S3-S1' subsites have been shown… 
1991
1991
Characterization of palytoxin-induced catecholamine secretion from cultured bovine adrenal chromaffin cells. Effects of Na(+)- and Ca(2+)-channel blockers.
1990
1990
Two types of sodium channel block by class-I antiarrhythmic drugs studied by using Vmax of action potential in single ventricular myocytes.
Highly Cited
1982
Highly Cited
1982
Electrophysiologic drug testing in prophylaxis of sporadic paroxysmal atrial fibrillation: technique, application, and efficacy in severely symptomatic preexcitation patients.
1980
1980
Study of moxaprindine with programmed electrical stimulation of the heart in patients with reentrant tachyarrhythmias.
Review
1980
Review
1980
Hemodynamic effects of newer antiarrhythmic drugs.
1977
1977
Quality of the ideal antiarrhythmic drug.
1976
1976
Suppression of Ouabain‐induced Ventricular Rhythms with Aprindine HCl: A Comparison with Other Antiarrhythmic Agents
Three groups of dogs were given ouabain (mean 60, μg/kg) until an accelerated ventricular escape (AVE) and repetitive ventricular… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)