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Thiotepa

Known as: Tris(1-aziridinyl)phosphine Sulfide, 1,1',1''-Phosphinothioyldynetrisaziridine, N,N',N''-triethylenethiophosphoramide 
A polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity… 
National Institutes of Health

Related topics

Related topics

39 relations
ACP protocolAlkylating Activity [MoA]CTCb regimenCarboplatin/Etoposide/Cyclophosphamide/Thiotepa

Broader (3)

Antineoplastic Agents, AlkylatingMyeloablative Agonistsaziridine

Narrower (16)

GirostanMATILDE regimenMTV protocolMVT protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Dual responsive, stabilized nanoparticles for efficient in vivo plasmid delivery.
Nucleic acid-based therapeutics, including plasmid DNA (pDNA) and small interfering RNA (siRNA), have been considered highly… 
Review
2003
Review
2003
General methods for iminosugar synthesis.
Recent iminosugar syntheses starting both from commercially available sugars and non-glycidic precursors, are reported in this… 
Highly Cited
1997
Highly Cited
1997
Isolated limb reperfusion with tumor necrosis factor and melphalan in patients with extremity melanoma after failure of isolated limb perfusion with chemotherapeutics
This retrospective study evaluated the benefit of using tumor necrosis factor (TNF) and melphalan administered via an isolated… 
Highly Cited
1990
Highly Cited
1990
In vivo effects of single or combined dietary antimutagens on mutagen-induced chromosomal aberrations.
  • H. Renner
  • Mutation research
  • 1990
  • Corpus ID: 9555222
Highly Cited
1990
Highly Cited
1990
Preclinical studies relating to the use of thiotepa in the high-dose setting alone and in combination.
In vitro and in vivo studies with N,N',N''-triethylene-thiophosphoramide (thiotepa) alone and in combination with… 
Highly Cited
1983
Highly Cited
1983
Improvement in survival produced by sequential therapies in the treatment of recurrent medulloblastoma
Thirty‐six patients with recurrent medulloblastoma were treated with various combination chemotherapy protocols after initial… 
Highly Cited
1981
Highly Cited
1981
Evaluation of transport and storage techniques for isolation of Campylobacter fetus subsp. jejuni from turkey cecal specimens
Immediate culturing of fecal specimens is not always possible, and appropriate methods for transport and storage of Campylobacter… 
Highly Cited
1971
Highly Cited
1971
Use of Triethylenethiophosphoramide as an Adjuvant to the Surgical Treatment of Gastric and Colorectal Carcinoma: Ten‐Year Follow‐up
Highly Cited
1961
Highly Cited
1961
Metabolic adaptations in rat hepatomas. II. Tryptophan pyrrolase and tyrosine alpha-ketoglutarate transaminase.
Summary The administration of tryptophan or cortisone to rats bearing the Morris 5123 Hepatoma resulted in significant increases… 
Highly Cited
1958
Highly Cited
1958
Thio-Thiophthen: an Unusual New Type of Aromatic System
IN the present communication we report our preliminary findings in researches on a series of sulphurated cyclic compounds… 
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