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Thiotepa

Known as: Tris(1-aziridinyl)phosphine Sulfide, 1,1',1''-Phosphinothioyldynetrisaziridine, N,N',N''-triethylenethiophosphoramide 
A polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity… Expand
National Institutes of Health

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Highly Cited
1999
Highly Cited
1999
Isatin, its 5-chloro and 5-bromo derivatives have been reacted with N-[4-(4'-chlorophenyl)thiazol-2-yl] thiosemicarbazide to form… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND In this study we tried to achieve successful transplantation in patients with acute leukemia with the use of… Expand
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Highly Cited
1993
Highly Cited
1993
PURPOSE This prospective randomized cooperative group study was conducted in patients with neoplastic meningitis treated with… Expand
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Highly Cited
1993
Highly Cited
1993
EMT-6 murine mammary tumor sublines highly resistant to cyclophosphamide, cis-diamminedichloro-platinum(II), or N,N',N… Expand
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Highly Cited
1992
Highly Cited
1992
PURPOSE The study was designed to determine the duration of complete response (CR) for patients with unresectable or metastatic… Expand
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Highly Cited
1991
Highly Cited
1991
N-(5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N- methylamino]-2-thenoyl)-L-glutamic acid (ICI D1694) is a water… Expand
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Highly Cited
1982
Highly Cited
1982
  • S. Brosman
  • The Journal of urology
  • 1982
  • Corpus ID: 26320861
A randomized study was done on 49 patients with a history of recurrent superficial transitional cell carcinoma of the bladder to… Expand
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Highly Cited
1979
Highly Cited
1979
  • W. Bruce, J. Heddle
  • Canadian journal of genetics and cytology…
  • 1979
  • Corpus ID: 30832918
A comparison of two rapid and inexpensive in vivo mammalian assays and the Ames Salmonella assay is presented for 61 agents… Expand
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Highly Cited
1975
Highly Cited
1975
  • A. Wyrobek, W. Bruce
  • Proceedings of the National Academy of Sciences…
  • 1975
  • Corpus ID: 36406213
The sperm of (C57BL X C3H)F1 mice were examined 1, 4, and 10 weeks after a subacute treatment with one of 25 chemicals at two or… Expand
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Highly Cited
1975
Highly Cited
1975
In 1958, a co-operative clinical trial, involving 23 institutions, was begun to evaluate the efficacy of a short course of… Expand
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