Thiotepa

Known as: Tris(1-aziridinyl)phosphine Sulfide, 1,1',1''-Phosphinothioyldynetrisaziridine, N,N',N''-triethylenethiophosphoramide 
A polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity… (More)
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
We used human liver microsomes (HLMs) and recombinant cytochromes P450 (P450s) to identify the routes of efavirenz metabolism and… (More)
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Highly Cited
1999
Highly Cited
1999
Previous studies have demonstrated a synergistic interaction between rhuMAb HER2 and the cytotoxic drug cisplatin in human breast… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND In this study we tried to achieve successful transplantation in patients with acute leukemia with the use of… (More)
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Highly Cited
1998
Highly Cited
1998
PURPOSE Medulloblastoma is a highly lethal disease when it recurs. Very few patients survive with conventional treatment. This… (More)
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Highly Cited
1996
Highly Cited
1996
PURPOSE This study was designed to determine the toxicity, radiographic response rate, and outcome following high-dose thiotepa… (More)
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Highly Cited
1995
Highly Cited
1995
The CD34 antigen is expressed by committed and uncommitted hematopoietic progenitor cells and is increasingly used to assess stem… (More)
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Highly Cited
1993
Highly Cited
1993
PURPOSE This prospective randomized cooperative group study was conducted in patients with neoplastic meningitis treated with… (More)
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Highly Cited
1993
Highly Cited
1993
EMT-6 murine mammary tumor sublines highly resistant to cyclophosphamide, cis-diamminedichloro-platinum(II), or N,N',N… (More)
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Highly Cited
1992
Highly Cited
1992
PURPOSE The study was designed to determine the duration of complete response (CR) for patients with unresectable or metastatic… (More)
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Highly Cited
1991
Highly Cited
1991
N-(5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N- methylamino]-2-thenoyl)-L-glutamic acid (ICI D1694) is a water… (More)
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