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Thiotepa

Known as: Tris(1-aziridinyl)phosphine Sulfide, 1,1',1''-Phosphinothioyldynetrisaziridine, N,N',N''-triethylenethiophosphoramide 
A polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity… 
National Institutes of Health

Related topics

Related topics

39 relations
ACP protocolAlkylating Activity [MoA]CTCb regimenCarboplatin/Etoposide/Cyclophosphamide/Thiotepa

Broader (3)

Antineoplastic Agents, AlkylatingMyeloablative Agonistsaziridine

Narrower (16)

GirostanMATILDE regimenMTV protocolMVT protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Dual responsive, stabilized nanoparticles for efficient in vivo plasmid delivery.
Nucleic acid-based therapeutics, including plasmid DNA (pDNA) and small interfering RNA (siRNA), have been considered highly… 
Highly Cited
2009
Highly Cited
2009
Chitosan based oligoamine polymers: synthesis, characterization, and gene delivery.
Highly Cited
2005
Highly Cited
2005
ROS formation and glutathione levels in human oral fibroblasts exposed to TEGDMA and camphorquinone.
Glutathione (GSH) is important for the self-protection of cells against oxidative stress and toxic xenobiotics, whereas reactive… 
Highly Cited
1997
Highly Cited
1997
Isolated limb reperfusion with tumor necrosis factor and melphalan in patients with extremity melanoma after failure of isolated limb perfusion with chemotherapeutics
This retrospective study evaluated the benefit of using tumor necrosis factor (TNF) and melphalan administered via an isolated… 
Highly Cited
1991
Highly Cited
1991
Development of scleral ulceration and calcification after pterygium excision and mitomycin therapy.
Highly Cited
1989
Highly Cited
1989
Allergic contact dermatitis from dental composite resins due to aromatic epoxy acrylates mid aliphatic acrylates
7 patients were occupationally sensitized to dental composite resin products (DCR): 6 dental nurses and 1 dentist. All had a… 
Highly Cited
1987
Highly Cited
1987
Cyclic AMP induces changes in distribution and transport of organelles within growth cones of Aplysia bag cell neurons
This report examines cAMP-induced regulation of directed organelle transport in bag cell neuron growth cones using video-enhanced… 
Highly Cited
1984
Highly Cited
1984
Comparison of 6-thioguanine-resistant mutation and sister chromatid exchanges in Chinese hamster V79 cells with forty chemical and physical agents.
The induction of sister chromatid exchanges (SCE) and mutation at the hypoxanthine-guanine phosphoribosyl transferase locus and… 
Highly Cited
1971
Highly Cited
1971
Use of Triethylenethiophosphoramide as an Adjuvant to the Surgical Treatment of Gastric and Colorectal Carcinoma: Ten‐Year Follow‐up
Review
1957
Review
1957
Leukocyte agglutinins in human sera; correlation between blood transfusions and their development.
Introduction The discovery of autoantibodies for erythrocytes in acquired hemolytic anemia (AHA)* and for platelets in idiopathic… 
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