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Thiotepa

Known as: Tris(1-aziridinyl)phosphine Sulfide, 1,1',1''-Phosphinothioyldynetrisaziridine, N,N',N''-triethylenethiophosphoramide 
A polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity… 
National Institutes of Health

Related topics

Related topics

39 relations
ACP protocolAlkylating Activity [MoA]CTCb regimenCarboplatin/Etoposide/Cyclophosphamide/Thiotepa

Broader (3)

Antineoplastic Agents, AlkylatingMyeloablative Agonistsaziridine

Narrower (16)

GirostanMATILDE regimenMTV protocolMVT protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Dual responsive, stabilized nanoparticles for efficient in vivo plasmid delivery.
Nucleic acid-based therapeutics, including plasmid DNA (pDNA) and small interfering RNA (siRNA), have been considered highly… 
Highly Cited
2005
Highly Cited
2005
ROS formation and glutathione levels in human oral fibroblasts exposed to TEGDMA and camphorquinone.
Glutathione (GSH) is important for the self-protection of cells against oxidative stress and toxic xenobiotics, whereas reactive… 
Review
2003
Review
2003
General methods for iminosugar synthesis.
Recent iminosugar syntheses starting both from commercially available sugars and non-glycidic precursors, are reported in this… 
Highly Cited
1997
Highly Cited
1997
Isolated limb reperfusion with tumor necrosis factor and melphalan in patients with extremity melanoma after failure of isolated limb perfusion with chemotherapeutics
This retrospective study evaluated the benefit of using tumor necrosis factor (TNF) and melphalan administered via an isolated… 
Highly Cited
1990
Highly Cited
1990
In vivo effects of single or combined dietary antimutagens on mutagen-induced chromosomal aberrations.
  • H. Renner
  • Mutation research
  • 1990
  • Corpus ID: 9555222
Highly Cited
1990
Highly Cited
1990
Preclinical studies relating to the use of thiotepa in the high-dose setting alone and in combination.
In vitro and in vivo studies with N,N',N''-triethylene-thiophosphoramide (thiotepa) alone and in combination with… 
Highly Cited
1987
Highly Cited
1987
Cyclic AMP induces changes in distribution and transport of organelles within growth cones of Aplysia bag cell neurons
This report examines cAMP-induced regulation of directed organelle transport in bag cell neuron growth cones using video-enhanced… 
Highly Cited
1983
Highly Cited
1983
Improvement in survival produced by sequential therapies in the treatment of recurrent medulloblastoma
Thirty‐six patients with recurrent medulloblastoma were treated with various combination chemotherapy protocols after initial… 
Highly Cited
1981
Highly Cited
1981
Evaluation of transport and storage techniques for isolation of Campylobacter fetus subsp. jejuni from turkey cecal specimens
Immediate culturing of fecal specimens is not always possible, and appropriate methods for transport and storage of Campylobacter… 
Highly Cited
1971
Highly Cited
1971
Use of Triethylenethiophosphoramide as an Adjuvant to the Surgical Treatment of Gastric and Colorectal Carcinoma: Ten‐Year Follow‐up
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