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aziridine

Known as: Dimethylenimine, ETHYLENEIMINE, Azirane 
A monofunctional alkylating agent with potential antineoplastic activity. Reacting with DNA mainly at guanine and adenine residues, ethylenimine… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

Aziridinesnitrogenous heterocyclic compound
Ethyleneimine:MCnc:Pt:Air:QnNCIt Antineoplastic Agent Terminologydiaziquoneoxaziridine

Narrower (1)

Thiotepa

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Polyaspartamide-based oligo-ethylenimine brushes with high buffer capacity and low cytotoxicity for highly efficient gene delivery.
Polyaspartamide-based oligo-ethylenimine brushes (PASP-EDA, PASP-TEPA, PASP-PEHA, and PASP-PEI 423) were synthesized from… 
1983
1983
Synthesis and biological activity of a 2-bromoethylamine (mustard) derivative of hemicholinium-3 and hemicholinium-15.
Work on the synthesis and investigation into the biological activity of a 2-bromoethylamine (mustard) analogue of hemicholinium-3… 
1982
1982
Modification of catalytic groups in lysozyme with ethylenimine.
The reaction of lysozyme with ethylenimine has been studied at neutral and acidic pH. At least four singly modified lysozyme… 
1978
1978
Studies related to antitumor antibiotics. Part XIV. Reactions of mitomycin B with DNA.
The reactions of the antitumor antibiotic mitomycin B with DNA were examined using ethidium fluorescence assays. The following… 
Highly Cited
1972
Highly Cited
1972
Mutagenicity of chemical carcinogens in Neurospora crassa.
The mutagenicity of the aflatoxine (B1, B2, G1, and G2), 1,2,3,4-diepoxycyclohexane, 1,2,4,5-diepoxypentane, 1,2,7,8… 
Highly Cited
1961
Highly Cited
1961
Antifertility substances and their assessment in the male rodent.
The antifertility effects of simple alkane sulphonic esters have been examined in the male rat by a combination of serial mating… 
1961
1961
[Recombination of Actinomyces aureofaciens].
1958
1958
Tumour-inhibiting Action of 1 : 6-Dimethanesulphonyl-D-mannitol
EXTENSIVE clinical experience with ‘Myleran’ (I, n= 4) in the treatment of chronic myeloid leukæmia1 has shown that when over… 
1952
1952
Inhibition of the crocker mouse sarcoma 180 by certain ethylenimine derivatives and related compounds
ERTAIN ETHYLENIMINES have been of interC est to the textile industry because of their chemical reactivity.7 This reactivity, as… 
1950
1950
RETARDATION of tumor growth in mice by oral administration of ethylenimine derivatives.