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diaziquone

Known as: 2,5-bis(1-aciridinyl)-3,6-bis(ethoxycarbonylamino)-1,4-benzoquinone, 1,4-cyclohexadiene-1,4-dicarbamic acid, 2, 5-bis(1-aziridinyl)-3,6-dioxo-, diethyl ester, Aziridinyl Benzoquinone 
A water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity. Bioactivation of aziridinylbenzoquinone RH1 occurs through… Expand
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Chloroquine (CQ), N'-(7-chloroquinolin-4-yl)-N,N-diethyl-pentane-1,4-diamine, is widely used as an effective and safe anti… Expand
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Highly Cited
2004
Highly Cited
2004
Although pesticide use is widespread, little is known about potential adverse health effects of in utero exposure. We… Expand
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Review
2004
Review
2004
  • D. Ross
  • Drug metabolism reviews
  • 2004
  • Corpus ID: 32257389
The multiple functions of NAD(P)H:quinone oxidoreductase 1 (NQO1, DT‐diaphorase) in the cell are reviewed. NQO1 has long been… Expand
Highly Cited
2002
Highly Cited
2002
A PBPK/PD model was developed for the organophosphate insecticide chlorpyrifos (CPF) (O,O-diethyl-O-[3,5,6-trichloro-2-pyridyl… Expand
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Highly Cited
2002
Highly Cited
2002
We measured two diethyl organophosphorus (OP) pesticides--chlorpyrifos and parathion--in residences, and their metabolic by… Expand
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Highly Cited
2000
Highly Cited
2000
Recent studies have indicated that a complex machinery of transactivation of target genes by estrogen or antiestrogen through… Expand
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Highly Cited
1999
Highly Cited
1999
Systemin is an important mediator of wound-induced defense gene activation in tomato plants, and it elicits a rapid… Expand
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Highly Cited
1998
Highly Cited
1998
NAD(P)H:quinone oxidoreductase (NQO1) is a flavoenzyme that catalyzes the two-electron reduction of quinones and related… Expand
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Highly Cited
1980
Highly Cited
1980
L-Glutamic acid (Glu) and L-aspartic acid (Asp) are putative excitatory transmitters in the mammalian central nervous system (CNS… Expand
Highly Cited
1946
Highly Cited
1946
IN a previous letter in Nature1, chemical substances were mentioned which are as effective as X-rays in inducing mutations and… Expand