diaziquone

Known as: 2,5-bis(1-aciridinyl)-3,6-bis(ethoxycarbonylamino)-1,4-benzoquinone, 1,4-cyclohexadiene-1,4-dicarbamic acid, 2, 5-bis(1-aziridinyl)-3,6-dioxo-, diethyl ester, Aziridinyl Benzoquinone 
A water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity. Bioactivation of aziridinylbenzoquinone RH1 occurs through… (More)

Topic mentions per year

Topic mentions per year

1942-2017
010203019422016

Papers overview

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2004
2004
Glyceryl prostaglandins (PG-Gs) are generated by the oxygenation of the endocannabinoid, 2-arachidonylglycerol, by cyclooxygenase… (More)
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2000
2000
This study compares the effect of plant stanol ester spread with a placebo spread on cholesterol in patients taking statin… (More)
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1998
1998
NAD(P)H:quinone oxidoreductase (NQO1; DT-diaphorase) is elevated in certain tumors, such as non-small cell lung cancer (NSCLC… (More)
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1994
1994
1. Serum cholesterol reduction and changes in cholesterol metabolism were studied during rapeseed oil feeding without and with… (More)
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1990
1990
Reduction of 2,5-diaziridinyl-3,6-bis(carboethoxyamino)-1,4-benzoquinone (diaziquone; AZQ) by purified rat hepatic DT-diaphorase… (More)
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Highly Cited
1988
Highly Cited
1988
Eight consecutive patients with recurrent malignant oligodendroglioma were treated with systemic chemotherapy. Six patients… (More)
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1987
1987
Cell strains derived by culture of malignant glioma (astrocytoma grade III-IV) surgical specimens were tested for the production… (More)
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1985
1985
In order to understand the redox properties of diaziquone (AZQ) and the reductive alkylation role of its one-electron reduced… (More)
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1983
1983
Two human brain tumors which were previously established in nude mice were used to determine antitumor efficacy of various… (More)
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