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diaziquone

Known as: 2,5-bis(1-aciridinyl)-3,6-bis(ethoxycarbonylamino)-1,4-benzoquinone, 1,4-cyclohexadiene-1,4-dicarbamic acid, 2, 5-bis(1-aziridinyl)-3,6-dioxo-, diethyl ester, Aziridinyl Benzoquinone 
A water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity. Bioactivation of aziridinylbenzoquinone RH1 occurs through… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (5)

1,4-benzoquinoneAntineoplastic AgentsAziridinesBenzoquinones

Narrower (2)

CI-904NSC 182986
NCIt Antineoplastic Agent Terminologyaziridinecyclophosphamide/diaziquone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: structure-activity relationships for cytotoxicity and antitumor activity.
A large number of aziridinyl quinones represented by series 1-9 were studied with respect to their DT-diaphorase substrate… 
Highly Cited
2000
Highly Cited
2000
Susceptibility of Five Nontarget Organisms to Aqueous Diazinon Exposure
Diazinon (O,O-diethyl O-[2-isopropyl-6-methyl-4pyrimidinyl] phosphothioate) is an organophosphorus insecticide widely used on… 
Highly Cited
1986
Highly Cited
1986
Aluminum ions are required for stabilization and inhibition of hepatic microsomal glucose-6-phosphatase by sodium fluoride.
Highly Cited
1984
Highly Cited
1984
Characterization of the estrogen receptor and its dynamics in MCF-7 human breast cancer cells using a covalently attaching antiestrogen.
We have used a covalently attaching antiestrogen, tamoxifen aziridine [TA; (Z)-(1-[4-(2-[N-aziridinyl] ethoxy)phenyl])1,2… 
Highly Cited
1979
Highly Cited
1979
Triethyltin binding to cat haemoglobin. Evidence for two chemically distinct sites and a role for both histidine and cysteine residues.
Triethyltin binding to cat haemoglobin was measured after pretreatment of the protein with diethyl pyrocarbonate at pH 6.0… 
Highly Cited
1970
Highly Cited
1970
Effect of Four Organophosphorus Insecticides on Microbial Activities in Soil
Laboratory tests were conducted with four organophosphorus insecticides, Bay 37289 (O-ethyl O-2,4,5-trichlorophenyl… 
Highly Cited
1964
Highly Cited
1964
INTERACTION OF NUCLEIC ACIDS, I. PHYSICAL BINDING OF THYMINE, ADENINE, STEROIDS, AND AROMATIC HYDROCARBONS TO NUCLEIC ACIDS.
In a previous communication,' it was shown that the helix-coil transition temperature, Tm, of thymus DNA and helical poly A is… 
Highly Cited
1957
Highly Cited
1957
EFFECTS OF METABOLIC INHIBITORS AND DRUGS ON ION TRANSPORT AND OXYGEN CONSUMPTION IN ISOLATED FROG SKIN
Active ion (NaCl) transport across isolated frog skin is discussed in relation to sodium and potassium composition and to O2… 
Highly Cited
1952
Highly Cited
1952
The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. II. Diethyl p-nitrophenyl thionphosphate (E605) and analogues.
Bernard, R. M. & Odell, L. D. (1950). J. Lab. clin. Med. 35, 940. Bernfeld, P. & Fishman, W. H. (1950). Fed. Proc. 9, 150… 
Highly Cited
1952
Highly Cited
1952
THE inhibition of chymotrypsin by diethyl p-nitrophenyl phosphate.
The alkyl fluorophosphonates were first shown in 1940 (Adrian, Feldberg & Kilby, 1947) to be very powerful inhibitors of… 
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