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1,4-benzoquinone

Known as: 2,5-cyclohexadiene-1,4-dione, 1,4-Cyclohexadiene Dioxide, Para-quinone 
 

Topic mentions per year

Topic mentions per year

1945-2018
05010015019452017

Related topics

Related topics

7 relations
1,4-Benzoquinones

Broader (3)

BenzoquinonesQuinonescyclic ketone

Narrower (3)

NaphthoquinonesUbiquinonediaziquone

Related mentions per year

Related mentions per year

1940-2018
19401960198020002020
1,4-benzoquinone
Quinones
Ubiquinone
Naphthoquinones
diaziquone
cyclic ketone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Transformation of acetaminophen by chlorination produces the toxicants 1,4-benzoquinone and N-acetyl-p-benzoquinone imine.
The reaction of the common pain reliever acetaminophen (paracetamol, 4-acetamidophenol) with hypochlorite was investigated over… (More)
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2004
2004
1,4-Benzoquinone is a topoisomerase II poison.
Benzene is a human carcinogen that induces hematopoietic malignancies. It is believed that benzene does not initiate leukemias… (More)
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2002
2002
Albumin adducts of benzene oxide and 1,4-benzoquinone as measures of human benzene metabolism.
Albumin adducts of benzene oxide (BO-Alb) and 1,4-benzoquinone (1,4-BQ-Alb) were investigated among 134 workers exposed to… (More)
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Highly Cited
2001
Highly Cited
2001
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease.
Huntington's disease (HD) is a progressive neurodegenerative disorder with no effective treatment. Geldanamycin is a benzoquinone… (More)
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Highly Cited
2000
Highly Cited
2000
The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome.
Several important signaling proteins including transcription factors and protein kinases depend on heat shock protein (Hsp)-90… (More)
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Highly Cited
1998
Highly Cited
1998
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin
Purpose: Benzoquinone ansamycins are antibiotics with anticancer potential. First described as tyrosine kinase inhibitors, they… (More)
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Highly Cited
1995
Highly Cited
1995
Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association.
Cytosolic Raf-1 exists in a high molecular weight complex with the heat shock protein Hsp90, the purpose of which is unknown. The… (More)
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1995
1995
Purification and Characterization of a 1,4-Benzoquinone Reductase from the Basidiomycete Phanerochaete chrysosporium.
An intracellular, soluble 1,4-benzoquinone reductase was purified from agitated cultures of Phanerochaete chrysosporium and… (More)
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Highly Cited
1994
Highly Cited
1994
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.
The molecular mechanisms by which oncogenic tyrosine kinases induce cellular transformation are unclear. Herbimycin A… (More)
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1988
1988
Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution.
The chemical reaction of 1,4-benzoquinone with glutathione results in the formation of adducts that exhibit increasing degrees of… (More)
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