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1,4-benzoquinone

Known as: QUINONE, 2,5-cyclohexadiene-1,4-dione, 1,4-Cyclohexadiene Dioxide 
 
National Institutes of Health

Related topics

Related topics

8 relations
1,4-Benzoquinones

Broader (4)

BenzoquinonesIndicators and ReagentsQuinonescyclic ketone

Narrower (3)

NaphthoquinonesUbiquinonediaziquone

Papers overview

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Highly Cited
2005
Highly Cited
2005
Fluorescence spectroscopy reveals ubiquitous presence of oxidized and reduced quinones in dissolved organic matter.
Excitation-emission matrixes (EEMs) of 379 dissolved organic matter (DOM) samples from diverse aquatic environments were modeled… Expand
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Highly Cited
2002
Highly Cited
2002
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
Electrophiles formed during metabolic activation of chemical carcinogens and reactive oxygen species generated from endogenous… Expand
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Highly Cited
2001
Highly Cited
2001
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
Induction of phase 2 enzymes, which neutralize reactive electrophiles and act as indirect antioxidants, appears to be an… Expand
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Highly Cited
2000
Highly Cited
2000
Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages*
Electrophiles and reactive oxygen species have been implicated in the pathogenesis of many diseases. Transcription factor Nrf2… Expand
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Highly Cited
1997
Highly Cited
1997
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
The induction of phase II detoxifying enzymes is an important defense mechanism against intake of xenobiotics. While this group… Expand
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Highly Cited
1997
Highly Cited
1997
Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens.
Induction of phase 2 detoxication enzymes [e.g., glutathione transferases, epoxide hydrolase, NAD(P)H: quinone reductase, and… Expand
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Highly Cited
1994
Highly Cited
1994
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.
The molecular mechanisms by which oncogenic tyrosine kinases induce cellular transformation are unclear. Herbimycin A… Expand
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Highly Cited
1992
Highly Cited
1992
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
Consumption of vegetables, especially crucifers, reduces the risk of developing cancer. Although the mechanisms of this… Expand
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Highly Cited
1991
Highly Cited
1991
The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity.
We have characterized further the antioxidant responsive element (ARE) identified in the 5'-flanking region of the rat… Expand
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Highly Cited
1985
Highly Cited
1985
Free-radical chemistry of cigarette smoke and its toxicological implications.
Cigarette smoke contains two very different populations of free radicals, one in the tar and one in the gas phase. The tar phase… Expand
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