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Aziridines

Known as: Dimethyleneimines, Azacyclopropanes, Saturated, Saturated Azacyclopropanes 
A compound with a three-atom ring containing nitrogen linked to two carbons. Ethylenimines are highly reactive alkylating reagents.
National Institutes of Health

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1,12-diaziridinyl-4,9-diazadodecane1,2-dimethyl-3-phenylaziridine1,6-anhydro-3,4-epiminoaltropyranose1-chloro-2,2-dimethylaziridine
In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

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Highly Cited
2010
Highly Cited
2010
Unprotected vinyl aziridines: facile synthesis and cascade transformations.
Functionalized vinylaziridines, readily available from water-stable aziridine aldehydes have led to the construction of a variety… 
2010
2010
Palladium-catalyzed domino ring-opening/carboxamidation reactions of N-tosyl aziridines and 2-iodothiophenols: a facile and efficient approach to 1,4-benzothiazepin-5-ones.
A novel and efficient domino procedure has been developed for the synthesis of 1,4-benzothiazepin-5-ones from simple and readily… 
Highly Cited
2008
Highly Cited
2008
Synthesis of chiral organocatalysts derived from aziridines: application in asymmetric aldol reaction.
We report the synthesis of a new series of highly efficient chiral organocatalysts derived via the regio- and stereoselective… 
2007
2007
Widening the usefulness of epoxides and aziridines in synthesis
Abstract Deprotonation of terminal epoxides and aziridines with organolithium/diamine combinations or lithium amides allows the… 
2005
2005
Chemistry of tetrathiomolybdate: aziridine ring opening reactions and facile synthesis of interesting sulfur heterocycles.
Benzyltriethylammonium tetrathiomolybdate, [BnEt3N]2MoS4, has been used successfully to effect ring opening of aziridines in a… 
2005
2005
Substituted aziridines by lithiation-electrophile trapping of terminal aziridines.
[reaction: see text] Regio- and stereoselective deprotonation of N-Bus (Bus = tert-butylsulfonyl)-protected terminal aziridines… 
Highly Cited
2003
Highly Cited
2003
Highly selective oxidative cleavage of beta-cyclodextrin-epoxide/aziridine complexes with IBX in water.
Water, an environmentally friendly reaction medium, has been utilized for the reaction of IBX with various epoxides 1 and… 
2002
2002
A concise, modular synthesis of chiral peraza-macrocycles using chiral aziridines.
[reaction: see text] Novel chiral peraza-macrocycles were synthesized from chiral aziridines as a common building block… 
1989
1989
Michael addition reactions of α β-ene-3′-phenylselenone of uridine. New synthesis of 2′,3′-dideoxy-ribo-aziridino-, 2′,3′-dideoxy-2′, 3′-ribo-cyclopropyl- & 2,2′-O-anhydro-3′-deoxy-3′-amino uridine…
Highly Cited
1987
Highly Cited
1987
Methamphetamine from Ephedrine: I. Chloroephedrines and Aziridines
Illicit methamphetamine clandestinely synthesized from ephedrine via reduction of chloroephedrine is discussed. The… 
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