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Thiorphan

Known as: (3-Mercapto-2-benzylpropionyl)glycine, Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)-, Thiorphan [Chemical/Ingredient] 
A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone… 
National Institutes of Health

Related topics

Related topics

14 relations
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Protease Inhibitors

Narrower (6)

S-acetylthiorphanazidothiorphandexecadotrilleucine thiorphan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Substance P and neurokinin A metabolism by cultured human skeletal muscle myocytes and fibroblasts
1993
1993
Metabolism of insect neuropeptides: properties of a membrane-bound endopeptidase from heads of Musca domestica.
1989
1989
Antidepressant action of imipramine and iprindole in mice is enhanced by inhibitors of enkephalin-degrading peptidases.
Highly Cited
1987
Highly Cited
1987
Antinociceptive action of cholecystokinin octapeptide (CCK 8) and related peptides in rats and mice: Effects of naloxone and peptidase inhibitors
Highly Cited
1986
Highly Cited
1986
Dissociated effects of inhibitors of enkephalin-metabolising peptidases or naloxone on various nociceptive responses.
Highly Cited
1985
Highly Cited
1985
Assessment of the role of “enkephalinase” in cholecystokinin inactivation
Highly Cited
1984
Highly Cited
1984
Bidentate peptides: highly potent new inhibitors of enkephalin degrading enzymes.
1984
1984
Enkephalinase from rat kidney. Purification, characterization, and study of substrate specificity.
Highly Cited
1983
Highly Cited
1983
Participation of both ‘enkephalinase’ and aminopeptidase activities in the metabolism of endogenous enkephalins
Highly Cited
1982
Highly Cited
1982
Nociception, enkephalin content and dipeptidyl carboxypeptidase activity in brain of mice treated with exopeptidase inhibitors
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