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TNFRSF18 wt Allele

Known as: GITR-D, AITR, CD357 
Human TNFRSF18 wild-type allele is located in the vicinity of 1p36.3 and is approximately 3 kb in length. This allele, which encodes tumor necrosis… 
National Institutes of Health

Related topics

Related topics

9 relations
1p36.3ApoptosisCell SurvivalCytokine Signaling Process

Broader (1)

TNFRSF18 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
GITR Gene Deletion and GITR-Fc Soluble Protein Administration Inhibit Multiple Organ Failure Induced by Zymosan
Multiple organ dysfunction syndrome (MODS) is a systemic inflammatory event that can result in organ damage, failure, and high… 
2010
2010
Combining T-cell Vaccination and Application of Agonistic Anti-GITR mAb (DTA-1) Induces Complete Eradication of HPV Oncogene Expressing Tumors in Mice
We generated an adenovirus-based T-cell vaccine (Ad-p14) that reliably elicits T-cell responses to human papillomavirus (HPV… 
Highly Cited
2009
Highly Cited
2009
Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy
A number of monoclonal antibodies (mAbs) have been studied for their ability to enhance immune responses. Although these… 
Highly Cited
2008
Highly Cited
2008
CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis.
BACKGROUND An increased CD4(+) CD25(+) T-cell population is observed in Wegener's granulomatosis (WG). This T-cell population is… 
Highly Cited
2006
Highly Cited
2006
Proinflammatory Role of Glucocorticoid-Induced TNF Receptor-Related Gene in Acute Lung Inflammation1
Glucocorticoid-induced TNFR-related gene (GITR) participates in the immune/inflammatory response. Because GITR expression has… 
2006
2006
Engagement of Glucocorticoid-Induced TNF Receptor Costimulates NKT Cell Activation In Vitro and In Vivo1
Glucocorticoid-induced TNF receptor (GITR) is known to provide costimulatory signals to CD4+CD25− and CD4+CD25+ T cells during… 
2005
2005
The Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Gene Modulates the Response to Candida albicans Infection
ABSTRACT The glucocorticoid-induced tumor necrosis factor (TNF) receptor-related gene (GITR; TNFRSF18) modulates immune response… 
2005
2005
CD28 regulates glucocorticoid-induced TNF receptor family-related gene expression on CD4+ T cells via IL-2-dependent mechanisms.
2004
2004
Glucocorticoid‐induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock
In the present study, we used glucocorticoid‐induced tumor necrosis factor (TNF) receptor family gene knockout (GITR‐KO) mice to… 
Highly Cited
2004
Highly Cited
2004
TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death.
T lymphocytes (pivotal in many inflammatory pathologies) are targets for glucocorticoid hormone (GC). How TCR-mediated activation… 
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