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TNFRSF18 gene

Known as: TNFRSF18, GITR, AITR 
This gene is involved in T-cell function.
National Institutes of Health

Related topics

Related topics

9 relations
ApoptosisCell SurvivalCytokine Signaling ProcessGlucocorticoid-Induced TNFR-Related Protein

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TNFRSF18 wt Allele

Papers overview

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Review
2017
Review
2017
Harnessing co-stimulatory TNF receptors for cancer immunotherapy: Current approaches and future opportunities.
Co-stimulatory tumor necrosis factor receptors (TNFRs) can sculpt the responsiveness of T cells recognizing tumor-associated… 
2011
2011
Novel regulatory SNPs in the promoter region of the TNFRSF18 gene in a Gabonese population.
Parasites are accountable for driving diversity within immune gene families. We identified and investigated regulatory single… 
2010
2010
Combining T-cell Vaccination and Application of Agonistic Anti-GITR mAb (DTA-1) Induces Complete Eradication of HPV Oncogene Expressing Tumors in Mice
We generated an adenovirus-based T-cell vaccine (Ad-p14) that reliably elicits T-cell responses to human papillomavirus (HPV… 
2008
2008
Co-immunization of mice with a retroviral DNA vaccine and GITRL-encoding plasmid augments vaccine-induced protection against retrovirus infection.
After more than 30 years of research a HIV vaccine is still not at hand. DNA vectors expressing viral antigens are very safe… 
2007
2007
Expression of AITR and AITR ligand in breast cancer patients.
Human activation-inducible TNF receptor (AITR) is a new member of the tumor necrosis factor family and expressed on peripheral… 
Highly Cited
2006
Highly Cited
2006
Glucocorticoid‐induced tumour necrosis factor receptor family related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques
Glucocorticoid‐induced tumour necrosis factor receptor family related protein (GITR) is the 18th member of the tumour necrosis… 
Highly Cited
2005
Highly Cited
2005
Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L
Recent evidence has resurrected the concept of specialized populations of T lymphocytes that are able to suppress an antigen… 
2005
2005
Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-κB ligand (RANKL) in osteoclast cells
2005
2005
The Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Gene Modulates the Response to Candida albicans Infection
ABSTRACT The glucocorticoid-induced tumor necrosis factor (TNF) receptor-related gene (GITR; TNFRSF18) modulates immune response… 
Highly Cited
2002
Highly Cited
2002
Role of GITR in activation response of T lymphocytes.
In this study, we describe the generation and characterization of mice in which GITR gene (TNFRSF18 [tumor necrosis factor… 
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