Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L

@article{Calmels2005BypassingTI,
  title={Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L},
  author={Bastien Calmels and St{\'e}phane Paul and Nicolas Futin and Catherine Ledoux and Fabienne Stoeckel and Bruce R. Acres},
  journal={Cancer Gene Therapy},
  year={2005},
  volume={12},
  pages={198-205}
}
Recent evidence has resurrected the concept of specialized populations of T lymphocytes that are able to suppress an antigen-specific immune response. T-regulatory cells (T-reg) have been characterized as CD4+ CD25+ T cells. Previous reports describing differential gene expression analysis have shown that the glucocorticoid-induced tumor necrosis family… CONTINUE READING