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TAP1 protein, human

Known as: Peptide Supply Factor 1, ATP-Binding Cassette Sub-Family B Member 2, ABCB2 protein, human 
Antigen peptide transporter 1 (808 aa, ~87 kDa) is encoded by the human TAP1 gene. This protein plays a role in cytoplasmic antigen transport and… 
National Institutes of Health

Related topics

Related topics

30 relations
Adenosine TriphosphatasesAntigen Presentation PathwayAntigen ProcessingAntigen-Presenting Cells

Broader (1)

Antigen Peptide Transporter-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
TAP-inhibiting proteins US6, ICP47 and UL49.5 differentially affect minor and major histocompatibility antigen-specific recognition by cytotoxic T lymphocytes.
CTLs specific for hematopoietic system-restricted minor histocompatibility antigens (mHags) can serve as reagents for cellular… 
2004
2004
TAP1 and TAP2 polymorphism in coeliac disease
Coeliac disease is strongly associated with HLA-DQ2, but it is possible that additional major histocompatibility complex genes… 
2003
2003
Nucleotide Interactions with Membrane-bound Transporter Associated with Antigen Processing Proteins*
The transporter associated with antigen processing (TAP) contains two nucleotide-binding domains (NBD) in the TAP1 and TAP2… 
2002
2002
High frequency of a non-functional TAP1/LMP2 promoter polymorphism in human tumors.
The Tap1 and Tap2 genes encoding for a heterodimeric peptide transporter play a key role in antigen processing and presentation… 
2001
2001
Use of chimeric proteins to investigate the role of transporter associated with antigen processing (TAP) structural domains in peptide binding and translocation
The transporter associated with antigen processing (TAP) comprises two subunits, TAP1 and TAP2, each containing a hydrophobic… 
2000
2000
Pairing of the Nucleotide Binding Domains of the Transporter Associated with Antigen Processing*
The transporter associated with antigen processing (TAP) comprises two structurally related subunits, TAP1 and TAP2, that form… 
Review
1997
Review
1997
MHC class I antigen processing pathways.
1997
1997
Major histocompatibility complex class I molecules interact with both subunits of the transporter associated with antigen processing, TAP1 and TAP2
Prior to loading antigenic peptides, assembled major histocompatibility complex (MHC) class I molecules associate with the… 
1997
1997
Human TAP1 polymorphisms detected by denaturing gradient gel electrophoresis.
Presentation of endogenous peptides by major histocompatibility complex class I (MHC) molecules is controlled, in part, by the… 
1996
1996
Organization, transcription, and expression of the 5' region of the fla operon of Treponema phagedenis and Treponema pallidum
A locus encoding polypeptides associated with flagellar structure and function was identified, sequenced, and characterized in… 
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