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TAP1 protein, human
Known as:
Peptide Supply Factor 1
, ATP-Binding Cassette Sub-Family B Member 2
, ABCB2 protein, human
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Antigen peptide transporter 1 (808 aa, ~87 kDa) is encoded by the human TAP1 gene. This protein plays a role in cytoplasmic antigen transport and…
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National Institutes of Health
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Related topics
Related topics
30 relations
Adenosine Triphosphatases
Antigen Presentation Pathway
Antigen Processing
Antigen-Presenting Cells
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Broader (1)
Antigen Peptide Transporter-1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma
Akash M Mehta
,
E. Jordanova
,
G. Kenter
,
S. Ferrone
,
G. Fleuren
Cancer Immunology and Immunotherapy
2007
Corpus ID: 18083049
HLA class I loss is a significant mechanism of immune evasion by cervical carcinoma, interfering with the development of…
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Highly Cited
2004
Highly Cited
2004
Viral degradation of the MHC class I peptide loading complex.
J. Boname
,
B. D. de Lima
,
P. Lehner
,
P. Stevenson
Immunity
2004
Corpus ID: 37646292
Highly Cited
2000
Highly Cited
2000
Transcriptional regulation of the major histocompatibility complex (MHC) class I heavy chain, TAP1 and LMP2 genes by the human papillomavirus (HPV) type 6b, 16 and 18 E7 oncoproteins
N. T. Georgopoulos
,
J. Proffitt
,
G. Blair
Oncogene
2000
Corpus ID: 1795245
We have examined the possibility that the E7 proteins of the high-risk human papillomavirus (HPV) type 16 and 18 and the…
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Highly Cited
1998
Highly Cited
1998
ER‐60, a chaperone with thiol‐dependent reductase activity involved in MHC class I assembly
J. Lindquist
,
O. Jensen
,
M. Mann
,
G. Hämmerling
EMBO Journal
1998
Corpus ID: 1104729
The assembly of newly synthesized MHC class I molecules within the endoplasmic reticulum and their association with the…
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Highly Cited
1998
Highly Cited
1998
Different Requirements for Signal Transducer and Activator of Transcription 1α and Interferon Regulatory Factor 1 in the Regulation of Low Molecular Mass Polypeptide 2 and Transporter Associated with…
M. Chatterjee‐Kishore
,
R. Kishore
,
D. Hicklin
,
F. Marincola
,
S. Ferrone
Journal of Biological Chemistry
1998
Corpus ID: 33463698
The components of the antigen processing machinery, low molecular mass polypeptide (LMP) 2 and transporter associated with…
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Highly Cited
1998
Highly Cited
1998
HLA‐A*0201 presents TAP‐dependent peptide epitopes to cytotoxic T lymphocytes in the absence of tapasin
Jonathan W. Lewis
,
A. Sewell
,
David Price
,
Tim Elliott
European Journal of Immunology
1998
Corpus ID: 42469023
Tapasin is a 48‐kDa endoplasmic reticulum (ER)‐resident glycoprotein that binds to the transporter associated with antigen…
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Highly Cited
1994
Highly Cited
1994
Interaction of MHC class I molecules with the transporter associated with antigen processing.
W. Suh
,
M. Cohen-Doyle
,
K. Fruh
,
K. Wang
,
P. A. Peterson
,
D. B. Williams
Science
1994
Corpus ID: 2095162
The transporter associated with antigen processing (TAP) delivers cytosolic peptides into the endoplasmic reticulum (ER) where…
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Highly Cited
1994
Highly Cited
1994
Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2).
M. Androlewicz
,
B. Ortmann
,
P. van Endert
,
T. Spies
,
P. Cresswell
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 11128368
The transporter proteins associated with antigen processing (TAP proteins) transport antigenic peptides across the endoplasmic…
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Highly Cited
1994
Highly Cited
1994
TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but…
I. Bačík
,
J. Cox
,
R. Anderson
,
J. Yewdell
,
J. Bennink
Journal of Immunology
1994
Corpus ID: 21757380
Under most circumstances, cell surface MHC class I molecules display peptides derived from a cytosolic pool of proteins. The…
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Highly Cited
1993
Highly Cited
1993
TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective
J. Shepherd
,
T. Schumacher
,
+4 authors
S. Tonegawa
Cell
1993
Corpus ID: 42472216
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