TAP1 protein, human

Known as: Peptide Supply Factor 1, ATP-Binding Cassette Sub-Family B Member 2, ABCB2 protein, human 
Antigen peptide transporter 1 (808 aa, ~87 kDa) is encoded by the human TAP1 gene. This protein plays a role in cytoplasmic antigen transport and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
HLA class I loss is a significant mechanism of immune evasion by cervical carcinoma, interfering with the development of… (More)
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2006
2006
The transporter associated with antigen processing (TAP) translocates antigenic peptides from the cytosol into the endoplasmic… (More)
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2005
2005
In vivo studies suggest that vascular endothelial cells (ECs) can acquire and cross-present exogenous Ag on MHC-I but the… (More)
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2005
2005
Before exit from the endoplasmic reticulum (ER), MHC class I molecules transiently associate with the transporter associated with… (More)
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Highly Cited
2001
Highly Cited
2001
Human cytomegalovirus (HCMV) encodes several genes that disrupt the major histocompatibility complex (MHC) class I antigen… (More)
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2001
2001
Melanoma tumor thickness is a major prognostic factor. Thin lesions, however, may metastasize, and sometimes thick tumors may not… (More)
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2000
2000
We have examined the possibility that the E7 proteins of the high-risk human papillomavirus (HPV) type 16 and 18 and the… (More)
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Highly Cited
1999
Highly Cited
1999
Lateral diffusion of GFP-tagged H2Ld molecules in the ER membrane reports on their interaction with the TAP complex during… (More)
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Highly Cited
1996
Highly Cited
1996
The immediate early protein ICP47 of herpes simplex virus (HSV) inhibits the transporter for antigen processing (TAP)-mediated… (More)
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Highly Cited
1993
Highly Cited
1993
T cells detect infection of cells by recognizing peptide fragments of foreign proteins bound to class I molecules of the major… (More)
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