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Antigen Presentation Pathway

Known as: Antigen Processing and Presentation 
Invariant chain (Ii) associates with newly synthesized class II molecules in the endoplasmic reticulum (ER), an interaction that has been shown to… Expand
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Purpose: High-grade serous ovarian cancers are heterogeneous not only in terms of clinical outcome but also at the molecular… Expand
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Highly Cited
2004
Highly Cited
2004
The initiation of most cytotoxic immune responses requires MHC class I‐restricted presentation of internalized antigens to CD8+ T… Expand
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Review
2004
Review
2004
Defective ribosomal products provide an important supply of endogenous peptides for entry into the classic MHC class I antigen… Expand
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Review
2003
Review
2003
Presumably because of the selective pressure exerted by the immune system, many viruses have evolved proteins that interfere with… Expand
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Review
2003
Review
2003
The genes encoding the major components of the antigen processing and presentation pathway (MHC class II, invariant chain and HLA… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Human cytomegalovirus (HCMV) establishes persistent lifelong infections and replicates slowly. To withstand robust… Expand
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Highly Cited
2001
Highly Cited
2001
Experimental autoimmune encephalomyelitis (EAE) serves as a prototypic model for T cell–mediated autoimmunity. Vα14 natural… Expand
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Highly Cited
1999
Highly Cited
1999
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that causes life-threatening disease in patients who are… Expand
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Highly Cited
1999
Highly Cited
1999
Among bacterial toxins, the adenylate cyclase toxin of Bordetella pertussis (CyaA) has a unique mechanism of entry that consists… Expand
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Highly Cited
1990
Highly Cited
1990
MAJOR histocompatibility complex (MHC) class I molecules export peptides to the cell surface for surveillance by cytotoxic T… Expand
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