Skip to search formSkip to main contentSkip to account menu

T-Cell Differentiation in the Thymus

Known as: thymocyte differentiation, thymocyte cell differentiation, T cell differentiation in thymus 
The progression of T cell precursors in the thymus through many stages of maturation. These stages include regulated expression of the alpha and beta… 
National Institutes of Health

Related topics

Related topics

27 relations
ACKR2 geneCCBP2 protein, humanCCBP2 wt AlleleCCL17 gene

Narrower (2)

Thymic T-Cell Selectionimmature T cell proliferation in thymus

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Expression of the p56lckY505F Mutation in CD45-Deficient Mice Rescues Thymocyte Development
ABSTRACT Mice deficient in the transmembrane protein tyrosine phosphatase CD45 exhibit a block in thymocyte development. To… 
Review
1998
Review
1998
Molecular and cellular events in early thymocyte development.
Review
1998
Review
1998
In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development.
Highly Cited
1996
Highly Cited
1996
Interleukin-7 is a critical growth factor in early human T-cell development.
Highly purified human CD34+ fetal liver stem cells differentiate to mature T cells when seeded in vitro into isolated fetal… 
Highly Cited
1994
Highly Cited
1994
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points.
Highly Cited
1994
Highly Cited
1994
An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.
Highly Cited
1993
Highly Cited
1993
Selective thymocyte depletion in neonatal HIV-1 thymic infection
Objective:To determine the impact of HIV-1 infection on thymocyte development, and the role of thymic infection on the… 
Highly Cited
1992
Highly Cited
1992
Expression of cytokines and their receptors by human thymocytes and thymic stromal cells.
The repertoire of cytokine and cytokine receptor mRNA expressed by unstimulated human thymocytes and thymic stromal cells was… 
Highly Cited
1990
Highly Cited
1990
Soluble CD23 (Fc epsilon RII) and interleukin 1 synergistically induce early human thymocyte maturation
The ability of human thymus-derived CD7+CD2-CD3- cells to acquire mature T cell antigens was assessed. Purified CD7+ thymocytes… 
Highly Cited
1981
Highly Cited
1981
Delineation of human thymocyte differentiation pathways utilizing double-staining techniques with monoclonal antibodies.
Three new techniques have been introduced for the phenotypic analysis of human thymocytes and T cells. Monoclonal antibodies of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)