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T-Cell Differentiation in the Thymus

Known as: thymocyte differentiation, thymocyte cell differentiation, T cell differentiation in thymus 
The progression of T cell precursors in the thymus through many stages of maturation. These stages include regulated expression of the alpha and beta… Expand
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Human T cell leukemias can arise from oncogenes activated by specific chromosomal translocations involving the T cell receptor… Expand
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Highly Cited
2000
Highly Cited
2000
Phosphoinositide 3-kinases (PI3Ks) regulate fundamental cellular responses such as proliferation, apoptosis, cell motility, and… Expand
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Highly Cited
2000
Highly Cited
2000
Productive interaction of a T lymphocyte with an antigen-presenting cell results in the clustering of the T-cell antigen receptor… Expand
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Review
2000
Review
2000
Glucocorticoids are small lipophilic compounds that mediate their many biological effects by binding an intracellular receptor… Expand
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Highly Cited
1999
Highly Cited
1999
Notch proteins are cell surface receptors that mediate developmental cell specification events. To explore the function of murine… Expand
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Highly Cited
1999
Highly Cited
1999
The p42 and p44 mitogen-activated protein kinases (MAPKs), also called Erk2 and Erk1, respectively, have been implicated in… Expand
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Highly Cited
1996
Highly Cited
1996
THE zinc-finger transcription factor GATA-3 is expressed in haematopoietic cells and in the developing kidney and nervous system1… Expand
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Highly Cited
1993
Highly Cited
1993
The multiple biological activities of tumor necrosis factor (TNF) are mediated by two distinct cell surface receptors of 55 kd… Expand
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Highly Cited
1992
Highly Cited
1992
THE protein Lck (p56lck) has a relative molecular mass of 56,000 and belongs to the Src family of tyrosine kinases1–3. It is… Expand
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Highly Cited
1992
Highly Cited
1992
Analysis of mice carrying mutant T-cell antigen receptor (TCP) genes indicates that TCP-β gene rearrangement or expression is… Expand
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