T-Cell Differentiation in the Thymus

Known as: thymocyte differentiation, thymocyte cell differentiation, T cell differentiation in thymus 
The progression of T cell precursors in the thymus through many stages of maturation. These stages include regulated expression of the alpha and beta… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Recognition of self-antigens is required for regulatory T (Treg) cells to exert dominant tolerance. However, the mechanism by… (More)
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Highly Cited
2003
Highly Cited
2003
Defects in death receptor-mediated apoptosis have been linked to cancer and autoimmune disease in humans. The in vivo role of… (More)
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Highly Cited
2000
Highly Cited
2000
Phosphoinositide 3-kinases (PI3Ks) regulate fundamental cellular responses such as proliferation, apoptosis, cell motility, and… (More)
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Review
2000
Review
2000
Glucocorticoids are small lipophilic compounds that mediate their many biological effects by binding an intracellular receptor… (More)
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Highly Cited
2000
Highly Cited
2000
The multiplicity of Notch receptors raises the question of the contribution of specific isoforms to T-cell development. Notch3 is… (More)
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Highly Cited
1996
Highly Cited
1996
THE zinc-finger transcription factor GATA-3 is expressed in haematopoietic cells and in the developing kidney and nervous system1… (More)
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Highly Cited
1995
Highly Cited
1995
Two candidate genes for controlling thymocyte differentiation,T-cellfactor-1 (Tcf-1) and lymphoid enhancer-binding factor (Lef-1… (More)
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Highly Cited
1992
Highly Cited
1992
Analysis of mice carrying mutant T-cell antigen receptor (TCP) genes indicates that TCP-β gene rearrangement or expression is… (More)
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Highly Cited
1992
Highly Cited
1992
Analysis of mice carrying mutant T-cell antigen receptor (TCR) genes indicates that TCR-beta gene rearrangement or expression is… (More)
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Highly Cited
1988
Highly Cited
1988
The T-cell repertoire is elaborated by a still poorly understood process during which precursor cells arising in the bone marrow… (More)
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