Synucleins

Known as: Synuclein, Synucleins [Chemical/Ingredient] 
A family of homologous proteins of low MOLECULAR WEIGHT that are predominately expressed in the BRAIN and that have been implicated in a variety of… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases of the elderly people that have devastating… (More)
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Highly Cited
2010
Highly Cited
2010
Presynaptic nerve terminals release neurotransmitters repeatedly, often at high frequency, and in relative isolation from… (More)
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Highly Cited
2004
Highly Cited
2004
Aberrant alpha-synuclein degradation is implicated in Parkinson's disease pathogenesis because the protein accumulates in the… (More)
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Highly Cited
2003
Highly Cited
2003
Sporadic Parkinson's disease involves multiple neuronal systems and results from changes developing in a few susceptible types of… (More)
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Highly Cited
2003
Highly Cited
2003
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra and the formation of… (More)
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Highly Cited
2000
Highly Cited
2000
alpha-, beta-, and gamma-Synuclein, a novel family of neuronal proteins, has become the focus of research interest because alpha… (More)
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Review
1998
Review
1998
Synuclein proteins are produced, in vertebrates, by three genes. They share structural resemblance to apolipoproteins, but are… (More)
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Highly Cited
1998
Highly Cited
1998
alpha-Synuclein is a highly conserved presynaptic protein of unknown function. A mutation in the protein has been causally linked… (More)
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Highly Cited
1997
Highly Cited
1997
Parkinson's disease (PD) is a common neurodegenerative disorder with a lifetime incidence of approximately 2 percent. A pattern… (More)
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Highly Cited
1994
Highly Cited
1994
Two abundant proteins of 140 and 134 amino acids were purified and sequenced from human brain. They were identified through their… (More)
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