Skip to search formSkip to main contentSkip to account menu

Simvastatin

Known as: [1S-[1alpha,3alpha,7beta,8beta(2S*,4S*),8abeta]]-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2,2-dimethylbutanoate, 2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one, Simvastatine 
A lipid-lowering agent derived synthetically from a fermentation product of the fungus Aspergillus terreus. Hydrolyzed in vivo to an active… 
National Institutes of Health

Related topics

Related topics

42 relations
24 HR Niacin 1000 MG / Simvastatin 20 MG Extended Release Oral Tablet [Simcor]AmprenavirCYP3A7 protein, humanCoronary Artery Disease

Broader (4)

Anticholesteremic AgentsHydroxymethylglutaryl-CoA Reductase InhibitorsHypolipidemic AgentsLovastatin

Narrower (7)

MK-733SynvinolinVytorinZocor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
A position paper
Recruitment for the inaugural double-blind placebo-controlled trial investigating a cholesterol-lowering treatment for benefit in… 
Highly Cited
2007
Highly Cited
2007
Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with…
Review
2006
Review
2006
Statins: potential new indications in inflammatory conditions.
Review
2006
Review
2006
Trends in the prevalence, awareness, treatment, and control of cardiovascular disease risk factors among noninstitutionalized patients with a history of myocardial infarction and stroke.
Rates of hypertension, high low density lipoprotein (LDL) cholesterol, and diabetes mellitus awareness, treatment, and control… 
Highly Cited
2005
Highly Cited
2005
Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus.
BACKGROUND Switching from calcineurin inhibitors (CNIs) to sirolimus might improve renal function in chronic renal transplant… 
Highly Cited
2005
Highly Cited
2005
Current Controlled Trials in Cardiovascular Medicine
  • 2005
  • Corpus ID: 1637962
Highly Cited
2002
Highly Cited
2002
Statin Use and the Risk of Breast and Prostate Cancer
Background. Laboratory data suggest that the cholesterol-lowering “statin” drugs may have chemopreventive potential against… 
Highly Cited
2001
Highly Cited
2001
n−3 Polyunsaturated fatty acids and cardiovascular diseases: To whom, how much, preparations
An expert round table discussion on the relationship between intake of n−3 polyunsaturated fatty acids (PUFA) mainly of marine… 
Review
2001
Review
2001
Use of statins in CNS disorders
Highly Cited
1999
Highly Cited
1999
Rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)