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Lovastatin

Known as: 6-alpha-methylcompactin, 6alpha-Methylcompactin, 6?-methylcompactin 
A lactone metabolite isolated from the fungus Aspergillus terreus with cholesterol-lowering and potential antineoplastic activities. Lovastatin is… 
National Institutes of Health

Related topics

Related topics

41 relations
24 HR Lovastatin 20 MG / Niacin 500 MG Extended Release Oral Tablet [Advicor]CYP3A7 protein, humanCoronary Artery DiseaseDrug Allergy

Narrower (17)

6-hydroxyisocompactinL 157012L 647318L 669262

Broader (5)

Anticholesteremic AgentsEnzyme InhibitorsHydroxymethylglutaryl-CoA Reductase InhibitorsNaphthalenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Improving the ratio of monacolin K to citrinin production of Monascus purpureus NTU 568 under dioscorea medium through the mediation of pH value and ethanol addition.
Using dioscorea root as substrate of Monascus species was found to stimulate monacolin K (cholesterol-lowering agent) formation… 
Highly Cited
2006
Highly Cited
2006
In vivo hypolipidemic effects and safety of low dosage Monascus powder in a hamster model of hyperlipidemia
Monascus or more commonly known as red mold rice is fermented rice on which Monascus purpureus has been grown. It has been a… 
Highly Cited
2003
Highly Cited
2003
An Archaeal Chromosomal Autonomously Replicating Sequence Element from an Extreme Halophile, Halobacterium sp. Strain NRC-1
ABSTRACT We report on the identification and first cloning of an autonomously replicating sequence element from the chromosome of… 
Highly Cited
2000
Highly Cited
2000
Inhibitors of HMG-CoA reductase sensitize human smooth muscle cells to Fas-ligand and cytokine-induced cell death.
Highly Cited
1997
Highly Cited
1997
Quantitation of the Pool of Cholesterol Associated with Acyl-CoA:Cholesterol Acyltransferase in Human Fibroblasts*
The esterification of cholesterol in homogenates of human fibroblasts was explored as a means of estimating the size of the pool… 
Highly Cited
1991
Highly Cited
1991
Coronary aneurysms after stent placement: a suggestion of altered vessel wall healing in the presence of anti-inflammatory agents.
Highly Cited
1990
Highly Cited
1990
Post-translational modification of low molecular mass GTP-binding proteins by isoprenoid.
Highly Cited
1990
Highly Cited
1990
Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase…
Highly Cited
1988
Highly Cited
1988
Lovastatin, nicotinic acid, and rhabdomyolysis.
Excerpt To the Editor:We recently observed a case of severe rhabdomyolysis in a patient being treated with lovastatin and… 
Highly Cited
1988
Highly Cited
1988
Lovastatin and rhabdomyolysis.
Excerpt To the Editor:Lovastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme in… 
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