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Hydroxymethylglutaryl-CoA Reductase Inhibitors

Known as: HMG-CoA reductase inhibitors, Inhibitors, Hydroxymethylglutaryl-CoA Reductase, Reductase Inhibitors, Hydroxymethylglutaryl-CoA 
Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is… 
Review
2014
Review
2014
Aims Homozygous familial hypercholesterolaemia (HoFH) is a rare life-threatening condition characterized by markedly elevated… 
Review
2014
Review
2001
Review
2001
The beneficial effects of statins are the result of their capacity to reduce cholesterol biosyntesis, mainly in the liver, where… 
Review
2000
Review
2000
Statins (HMG-CoA reductase inhibitors) are used widely for the treatment of hypercholesterolemia. They inhibit HMG-CoA reductase… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND Oxidized low-density lipoprotein (ox-LDL) causes endothelial dysfunction in part by decreasing the availability of… 
Highly Cited
1998
Highly Cited
1998
The treatment of ischemic strokes is limited to prophylactic agents that block the coagulation cascade. Here, we show that… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND Angiographic studies of the regression of coronary artery disease are invasive and costly, and they permit only… 
Highly Cited
1997
Highly Cited
1997
Matrix metalloproteinases (MMPs) classically have been implicated in basement membrane destruction associated with late-stage… 
Highly Cited
1994
Highly Cited
1994
BACKGROUND This study aimed to determine if cholesterol-lowering therapy improves endothelium-dependent coronary vasomotion in…