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Hydroxymethylglutaryl-CoA Reductase Inhibitors

Known as: HMG-CoA reductase inhibitors, Inhibitors, Hydroxymethylglutaryl-CoA Reductase, Reductase Inhibitors, Hydroxymethylglutaryl-CoA 
Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol… 
National Institutes of Health

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Narrower (28)

6-hydroxyisocompactinAmlodipine / atorvastatinAtorvastatin calciumBMY 21950
CholesterolHydroxymethylglutaryl-CoA reductaseIn Bloodaspects of radiation effects

Papers overview

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2015
2015
PCSK9 inhibitors – past, present and future
Lowering low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular disease (CVD) morbidity and mortality. Statins are… 
2014
2014
Hypolipidemic and antioxidant activity of ethanolic extract of Symplocos racemosa Roxb. in hyperlipidemic rats: an evidence of participation of oxidative stress in hyperlipidemia.
Hypolipidemic and antioxidant activity profiles of ethanolic extracts of Symplocos racemosa (EESR) were studied by triton-WR1339… 
1998
1998
Tumor promoter induces high mobility group HMG-Y protein expression in transformation-sensitive but not -resistant cells
Elevated levels of high mobility group (HMG) nonhistone chromosomal proteins I and Y, alternatively spliced members of the HMG-I… 
1997
1997
Combination of Low-Dose Niacin and Pravastatin Improves the Lipid Profile in Diabetic Patients without Compromising Glycemic Control
OBJECTIVE: To determine the efficacy and tolerability of the addition of low-dose niacin (1.5 g/d) in a diabetic… 
1990
1990
Studies on the regulation of cholesterol 7 alpha-hydroxylase and HMG-CoA reductase in rat liver: effects of lymphatic drainage and ligation of the lymph duct.
Lymphatic drainage leads to a significant stimulation of both the cholesterol 7 alpha-hydroxylase and HMG-CoA reductase activity… 
1984
1984
Effects of Chenodeoxycholic and Ursodeoxycholic Acids on Lipid Metabolism and Gallstone Formation in the Prairie Dog
The prevention of cholesterol cholelithiasis by dietary chenodeoxycholic and ursodeoxycholic acids was studied in the male… 
Highly Cited
1978
Highly Cited
1978
Regulation by plasma lipoproteins of progesterone biosynthesis and 3-hydroxy-3-methyl glutaryl coenzyme a reductase activity in cultured human choriocarcinoma cells.
The regulation of both the activity of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG CoA) reductase [mevalonate-NADP… 
1977
1977
Effects of cholesterol feeding on synthesis and metabolism of cholesterol and bile acids in germfree rats.
The aim of the present investigation was to study the influence of cholesterol feeding on cholesterol synthesis and fecal… 
Highly Cited
1973
Highly Cited
1973
Regulatory effects of dietary sterols and bile acids on rat intestinal HMG CoA reductase.
The specific activity (concentration) of microsomal HMG CoA reductase of intestinal crypt cells was studied in rats fed sterols… 
Highly Cited
1972
Highly Cited
1972
Stimulatory effect of dietary lipid and cholestyramine on hepatic HMG CoA reductase.
The diurnal cycle of hepatic HMG CoA reductase activity was studied under conditions of controlled feeding where the percentage… 
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