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Hydroxymethylglutaryl-CoA Reductase Inhibitors

Known as: HMG-CoA reductase inhibitors, Inhibitors, Hydroxymethylglutaryl-CoA Reductase, Reductase Inhibitors, Hydroxymethylglutaryl-CoA 
Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in adults over 50 years old. Genetic… Expand
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Review
2016
Review
2016
James L. Januzzi, Jr, MD, FACC, Chair Luis C. Afonso, MBBS, FACC Anthony Bavry, MD, FACC Brendan M. Everett, MD, FACC… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Statins can regress coronary atheroma and lower clinical events. Although pre-clinical studies suggest procalcific… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Although poor medication adherence may contribute to inadequate diabetes control, ways to feasibly measure adherence in… Expand
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Review
2000
Review
2000
Statins (HMG-CoA reductase inhibitors) are used widely for the treatment of hypercholesterolemia. They inhibit HMG-CoA reductase… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Ischemia followed by reperfusion in the presence of polymorphonuclear leukocytes (PMNs) results in cardiac contractile… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Oxidized low-density lipoprotein (ox-LDL) causes endothelial dysfunction in part by decreasing the availability of… Expand
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Highly Cited
1998
Highly Cited
1998
The treatment of ischemic strokes is limited to prophylactic agents that block the coagulation cascade. Here, we show that… Expand
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Highly Cited
1997
Highly Cited
1997
Matrix metalloproteinases (MMPs) classically have been implicated in basement membrane destruction associated with late-stage… Expand
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Highly Cited
1997
Highly Cited
1997
OBJECTIVES This study sought to determine whether inhibitors of 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase affect… Expand
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