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Amprenavir

Known as: (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate, APV, amprenavir [Chemical/Ingredient] 
A synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background and Purpose— Acute vestibular syndrome (AVS) is often due to vestibular neuritis but can result from vertebrobasilar… Expand
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Highly Cited
2003
Highly Cited
2003
Background—In stable coronary artery disease (CAD), exercise training has well-documented positive effects on arterial… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The purpose of this study was to determine the effects of systemic exercise training on endothelium-mediated… Expand
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Highly Cited
1995
Highly Cited
1995
Recent work has suggested that some proportion of excitatory synapses on hippocampal CA1 pyramidal cells that express NMDA… Expand
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Highly Cited
1993
Highly Cited
1993
1. Excitatory postsynaptic currents (EPSCs) were recorded in CA3 pyramidal cells of hippocampal slices of 15‐ to 24‐day‐old rats… Expand
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Highly Cited
1992
Highly Cited
1992
BackgroundAn improved intravascular ultrasonic Doppler device could aid the clinical assessment of coronary hemodynamics. We… Expand
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Highly Cited
1992
Highly Cited
1992
The role of inflammatory cytokines in the pathogenesis of neurological diseases is not well understood. The neurotoxic effects of… Expand
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Highly Cited
1988
Highly Cited
1988
The antagonist pharmacology of glutamate neurotoxicity was quantitatively examined in murine cortical cell cultures. Addition of… Expand
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Highly Cited
1987
Highly Cited
1987
Intracortical infusion of the "N-methyl-D-aspartate" (NMDA) receptor blocker D,L-2-amino-5-phosphonovaleric acid (APV) renders… Expand
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Highly Cited
1983
Highly Cited
1983
1. The effects of excitatory amino acids and some antagonists applied by ionophoresis to stratum radiatum in the CA1 region of… Expand
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