Amprenavir

Known as: (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate, APV, amprenavir [Chemical/Ingredient] 
A synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.
National Institutes of Health

Related topics

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46 relations
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleAmprenavir or Fosamprenavir:Susc:Pt:Isolate:OrdQn:GenotypingAmprenavir:ACnc:Pt:Ser/Plas:QnAmprenavir:MCnc:Pt:Ser/Plas:Qn
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Broader (6)

Anti-HIV AgentsAntibiotics, AntitubercularCarbamatesHIV Protease Inhibitors
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Papers overview

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Highly Cited
2004
Highly Cited
2004
Investment under Uncertainty, Debt and Taxes
We present a capital budgeting valuation framework that takes into account both personal and corporate taxation. This has… (More)
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Highly Cited
2003
Highly Cited
2003
Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase.
BACKGROUND In stable coronary artery disease (CAD), exercise training has well-documented positive effects on arterial… (More)
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Highly Cited
1999
Highly Cited
1999
Role of P-Glycoprotein on the CNS Disposition of Amprenavir (141W94), an HIV Protease Inhibitor
Purpose. To determine the role of P-glycoprotein (Pgp) on the CNS penetration of the HIV protease inhibitor (PI) amprenavir… (More)
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Highly Cited
1995
Highly Cited
1995
Evidence for silent synapses: Implications for the expression of LTP
Recent work has suggested that some proportion of excitatory synapses on hippocampal CA1 pyramidal cells that express NMDA… (More)
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Highly Cited
1992
Highly Cited
1992
Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity.
BACKGROUND An improved intravascular ultrasonic Doppler device could aid the clinical assessment of coronary hemodynamics. We… (More)
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Highly Cited
1992
Highly Cited
1992
Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death.
The role of inflammatory cytokines in the pathogenesis of neurological diseases is not well understood. The neurotoxic effects of… (More)
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Highly Cited
1991
Highly Cited
1991
Synaptic physiology of horizontal connections in the cat's visual cortex.
Horizontal connections are a principal component of intrinsic cortical circuitry. They arise mainly from pyramidal cells and… (More)
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Highly Cited
1991
Highly Cited
1991
Postnatal maturation of the GABAergic system in rat neocortex.
1. The postnatal maturation of intracortical inhibitory circuitry and the development of responses to applied gamma-aminobutyric… (More)
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Highly Cited
1988
Highly Cited
1988
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
The antagonist pharmacology of glutamate neurotoxicity was quantitatively examined in murine cortical cell cultures. Addition of… (More)
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Highly Cited
1983
Highly Cited
1983
Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus.
1. The effects of excitatory amino acids and some antagonists applied by ionophoresis to stratum radiatum in the CA1 region of… (More)
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