Amprenavir

Known as: (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate, APV, amprenavir [Chemical/Ingredient] 
A synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
We present a capital budgeting valuation framework that takes into account both personal and corporate taxation. This has… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND In stable coronary artery disease (CAD), exercise training has well-documented positive effects on arterial… (More)
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Highly Cited
1999
Highly Cited
1999
Purpose. To determine the role of P-glycoprotein (Pgp) on the CNS penetration of the HIV protease inhibitor (PI) amprenavir… (More)
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Highly Cited
1995
Highly Cited
1995
Recent work has suggested that some proportion of excitatory synapses on hippocampal CA1 pyramidal cells that express NMDA… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND An improved intravascular ultrasonic Doppler device could aid the clinical assessment of coronary hemodynamics. We… (More)
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Highly Cited
1992
Highly Cited
1992
The role of inflammatory cytokines in the pathogenesis of neurological diseases is not well understood. The neurotoxic effects of… (More)
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Highly Cited
1991
Highly Cited
1991
Horizontal connections are a principal component of intrinsic cortical circuitry. They arise mainly from pyramidal cells and… (More)
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Highly Cited
1991
Highly Cited
1991
1. The postnatal maturation of intracortical inhibitory circuitry and the development of responses to applied gamma-aminobutyric… (More)
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Highly Cited
1988
Highly Cited
1988
The antagonist pharmacology of glutamate neurotoxicity was quantitatively examined in murine cortical cell cultures. Addition of… (More)
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Highly Cited
1983
Highly Cited
1983
1. The effects of excitatory amino acids and some antagonists applied by ionophoresis to stratum radiatum in the CA1 region of… (More)
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