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Hypolipidemic Agents

Known as: Antilipemics, Antilipemic Drugs, Antihyperlipemics 
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
National Institutes of Health

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4'-chlorodiazepam5-(tetradecyloxy)-2-furancarboxylic acidAntilipemic agentBezafibrate
In BloodLipidsaspects of radiation effectschemical synthesis

Papers overview

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Review
2008
Review
2008
Biological and pharmacological activities of iridoids: recent developments.
Iridoids represent a large group of cyclopenta[c]pyran monoterpenoids that occur wide-spread in nature, mainly in dicotyledonous… 
Highly Cited
2000
Highly Cited
2000
Up-Regulation of Peroxisome Proliferator-Activated Receptors (PPAR-α) and PPAR-γ Messenger Ribonucleic Acid Expression in the Liver in Murine Obesity: Troglitazone Induces Expression of PPAR…
Peroxisome proliferator-activated receptors (PPARs) are transcription factors that play an important role in the regulation of… 
Highly Cited
1997
Highly Cited
1997
Alterations in Lipoprotein Metabolism in Peroxisome Proliferator-activated Receptor α-deficient Mice*
The peroxisome proliferator-activated receptor-α (PPARα) controls gene expression in response to a diverse class of compounds… 
Highly Cited
1997
Highly Cited
1997
Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans.
Peroxisome proliferator-activated receptors (PPARs, α, β/δ, and γ) are members of the nuclear receptor superfamily of ligand… 
Highly Cited
1994
Highly Cited
1994
Plasma Level and Gene Polymorphism of Angiotensin‐Converting Enzyme in Relation to Myocardial Infarction
BackgroundThe angiotensin-converting enzyme (ACE) plays an important role in the production of angiotensin II and the degradation… 
Review
1993
Review
1993
Positive regulation of the peroxisomal β‐oxidation pathway by fatty acids through activation of peroxisome proliferator‐activated receptors (PPAR)
Review
1983
Review
1983
Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans.
In this critical review, I would like to provide a brief outline of the morphology, biochemical composition, distribution, and… 
Highly Cited
1978
Highly Cited
1978
Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds.
Highly Cited
1977
Highly Cited
1977
Three hypolipidemic drugs increase hepatic palmitoyl-coenzyme A oxidation in the rat.
Male rats treated with clofibrate, tibric acid, or Wy-14,643 show an 11- to 18-fold increase in the capacity of their livers to… 
Highly Cited
1975
Highly Cited
1975
Hepatic peroxisome proliferation: induction by two novel compounds structurally unrelated to clofibrate
Two hypolipidemic compounds [ 4-chloro-6(2,3-xylidino)-2-pyrimidinyl-thio] acetic acid, and 2-chloro-5(3,5… 
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