Hypolipidemic Agents

Known as: Antilipemics, Antilipemic Drugs, Antihyperlipemics 
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
National Institutes of Health

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Papers overview

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Review
2009
Review
2009
Hypertriglyceridemic Pancreatitis: Presentation and Management
Hypertriglyceridemia (HTG) is reported to cause 1–4% of acute pancreatitis (AP) episodes. HTG is also implicated in more than… (More)
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Highly Cited
2004
Highly Cited
2004
Pharmacy benefits and the use of drugs by the chronically ill.
CONTEXT Many health plans have instituted more cost sharing to discourage use of more expensive pharmaceuticals and to reduce… (More)
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Review
2004
Review
2004
The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity.
Peroxisome proliferator-activated receptors (PPARs) are transcription factors belonging to the superfamily of nuclear receptors… (More)
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Highly Cited
2001
Highly Cited
2001
Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the…
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a key regulator of lipid homeostasis in hepatocytes and target… (More)
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Highly Cited
1998
Highly Cited
1998
The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates.
Fibrates are widely used hypolipidemic drugs which activate the nuclear peroxisome proliferator-activated receptor (PPAR) alpha… (More)
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Highly Cited
1997
Highly Cited
1997
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta.
Fatty acids (FAs) and their derivatives are essential cellular metabolites whose concentrations must be closely regulated. This… (More)
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Highly Cited
1997
Highly Cited
1997
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.
Peroxisome proliferator-activated receptors (PPARs) alpha and gamma are key regulators of lipid homeostasis and are activated by… (More)
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Highly Cited
1997
Highly Cited
1997
Endocrine disrupters in the aquatic environment.
Possible mechanisms to explain endocrine effects on reproduction and sex differentiation are presented for selected… (More)
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Highly Cited
1995
Highly Cited
1995
Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III.
The hypolipidemic effect exerted by beta,beta'-tetramethyl-hexadecanedioic acid (Medica 16) is accounted for by enhanced… (More)
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Highly Cited
1972
Highly Cited
1972
Triton-induced hyperlipidemia in rats as an animal model for screening hypolipidemic drugs
We describe a screening test for hypolipidemic agents in which compounds are administered orally to fasted rats after a single… (More)
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