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Hypolipidemic Agents

Known as: Antilipemics, Antilipemic Drugs, Antihyperlipemics 
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
National Institutes of Health

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Related topics

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Narrower (44)

4'-chlorodiazepam5-(tetradecyloxy)-2-furancarboxylic acidAntilipemic agentBezafibrate
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In BloodLipidsaspects of radiation effectschemical synthesis
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Effects of a Mediterranean-Style Diet on Cardiovascular Risk Factors
Context Some experts attribute a low incidence of heart disease in Mediterranean countries to dietary habits. Contribution In… Expand
Highly Cited
2004
Highly Cited
2004
Pharmacy benefits and the use of drugs by the chronically ill.
CONTEXT Many health plans have instituted more cost sharing to discourage use of more expensive pharmaceuticals and to reduce… Expand
Review
2004
Review
2004
The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity.
Peroxisome proliferator-activated receptors (PPARs) are transcription factors belonging to the superfamily of nuclear receptors… Expand
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Review
2000
Review
2000
Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
Abstract: Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear… Expand
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Highly Cited
1997
Highly Cited
1997
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay.
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors controlling the expression of genes involved in… Expand
Highly Cited
1997
Highly Cited
1997
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta.
Fatty acids (FAs) and their derivatives are essential cellular metabolites whose concentrations must be closely regulated. This… Expand
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Highly Cited
1997
Highly Cited
1997
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.
Peroxisome proliferator-activated receptors (PPARs) alpha and gamma are key regulators of lipid homeostasis and are activated by… Expand
Highly Cited
1997
Highly Cited
1997
Alterations in Lipoprotein Metabolism in Peroxisome Proliferator-activated Receptor α-deficient Mice*
The peroxisome proliferator-activated receptor-α (PPARα) controls gene expression in response to a diverse class of compounds… Expand
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Review
1989
Review
1989
Biochemical mechanisms of induction of hepatic peroxisome proliferation.
The process of xenobiotic-induced proliferation of the cytoplasmic organelle, the peroxisome, in mammalian liver cells has… Expand
Highly Cited
1975
Highly Cited
1975
Hepatic peroxisome proliferation: induction by two novel compounds structurally unrelated to clofibrate
Two hypolipidemic compounds [ 4-chloro-6(2,3-xylidino)-2-pyrimidinyl-thio] acetic acid, and 2-chloro-5(3,5… Expand
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