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Hypolipidemic Agents

Known as: Antilipemics, Antilipemic Drugs, Antihyperlipemics 
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
National Institutes of Health

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Narrower (44)

4'-chlorodiazepam5-(tetradecyloxy)-2-furancarboxylic acidAntilipemic agentBezafibrate
In BloodLipidsaspects of radiation effectschemical synthesis

Papers overview

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Highly Cited
2002
Highly Cited
2002
Differential effects of fenofibrate or simvastatin treatment of rats on hepatic microsomal overt and latent diacylglycerol acyltransferase activities.
Hepatic triacylglycerol secretion is elevated in insulin-resistant states. Microsomal diacylglycerol acyltransferase (DGAT… 
Highly Cited
2001
Highly Cited
2001
Suppression of hepatocyte nuclear factor-4α by acyl-CoA thioesters of hypolipidemic peroxisome proliferators
Review
2001
Review
2001
New Evidence for Beneficial Effects of Statins Unrelated to Lipid Lowering
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (statins) constitute the single most powerful class of… 
Highly Cited
1992
Highly Cited
1992
Studies on antidiabetic agents. 11. Novel thiazolidinedione derivatives as potent hypoglycemic and hypolipidemic agents.
In the course of further chemical modification of the novel antidiabetic pioglitazone (AD-4833, U-72,107), a series of 5-[4-(2… 
Highly Cited
1989
Highly Cited
1989
Alkylthioacetic acids (3-thia fatty acids) as non-beta-oxidizable fatty acid analogues: a new group of hypolipidemic drugs. III. Dissociation of cholesterol- and triglyceride-lowering effects and the…
Previous work in this laboratory indicated that sulfur-substituted fatty acid analogues, 1.10-bis(carboxymethylthio)decane and… 
Highly Cited
1982
Highly Cited
1982
Specificity in the action of hypolipidemic drugs: increase of peroxisomal beta-oxidation largely dissociated from hepatomegaly and peroxisome proliferation in the rat.
Hypolipidemic drugs increased 3- to 4-fold the activity of the peroxisomal beta-oxidation system in rat liver, with modest or no… 
1975
1975
Effect of hypolipidemic drugs, nafenopin and clofibrate, on the concentration of ligandin and Z protein in rat liver.
Review
1974
Review
1974
Treatment of hyperlipidemia.
OVER the past decade considerable insight into the mechanisms involved in normal and abnormal lipid transport as well as the mode… 
Review
1973
Review
1973
POSSIBLE PROPERTIES OF MICROBODIES (PEROXISOMES) MICROBODY PROLIFERATION AND HYPOLIPIDEMIC DRUGS
M icrobodies (peroxisomes), the cytoplasmic constituents identified originally in kidney and liver, have only recently been… 
Review
1972
Review
1972
Hypolipidemic drugs and lipoprotein metabolism.
Insight into the mechanism of action and efficacy of hypolipidemic drugs has awaited the development of the current concepts of… 
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