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Bezafibrate

Known as: Propanoic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-, Bezafibratum, 2-(P-(2-(P-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid 
An agonist of peroxisome proliferator-activated receptor alpha (PPARalpha) with antilipidemic activity. Bezafibrate decreases triglyceride levels… 
National Institutes of Health

Related topics

Related topics

16 relations

Narrower (7)

AM 49Beza-LandeBeza-PurenBezalip
BéfizalIn Bloodagonistsanalogs & derivatives

Broader (1)

Hypolipidemic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Bezafibrate, a peroxisome proliferator-activated receptors agonist, decreases body temperature and enhances electroencephalogram delta-oscillation during sleep in mice.
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear receptor… 
2006
2006
The direct antioxidative and anti-inflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in…
Highly Cited
2005
Highly Cited
2005
Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis.
Prolonged administration of peroxisome proliferators to rodents typically leads to hepatocarcinogenesis. Peroxisome proliferator… 
2004
2004
Influence of lipid lowering fibrates on P-glycoprotein activity in vitro.
2002
2002
Peroxisome proliferator-activated receptor beta expression in human breast epithelial cell lines of tumorigenic and non-tumorigenic origin.
Highly Cited
1996
Highly Cited
1996
Calcium antagonists and mortality in patients with coronary artery disease: a cohort study of 11,575 patients.
Highly Cited
1990
Highly Cited
1990
Induction of fatty acid binding protein by peroxisome proliferators in primary hepatocyte cultures and its relationship to the induction of peroxisomal beta-oxidation.
Highly Cited
1989
Highly Cited
1989
Effects of treatment with clofibrate, bezafibrate, and ciprofibrate on the metabolism of cholesterol in rat liver microsomes.
The effects of treatment of rats with clofibrate, bezafibrate, and ciprofibrate on the hepatic metabolism of cholesterol were… 
Highly Cited
1985
Highly Cited
1985
Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid.
1983
1983
The rapid induction of liver glycerophosphate acyltransferase in mice by clofibrate, a hypolipidemic agent.
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