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MK-733
Known as:
MK 733
, MK733
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Simvastatin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme…
L. Cohen
,
A. V. van Vliet
,
L. Roodenburg
,
L. M. Jansen
,
M. Griffioen
Biochemical pharmacology
1993
Corpus ID: 38759272
1993
1993
Effect of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor on triglyceride kinetics in chronically streptozotocin-diabetic rats.
E. Maeda
,
G. Yoshino
,
+5 authors
T. Kazumi
Metabolism: clinical and experimental
1993
Corpus ID: 20548244
Highly Cited
1992
Highly Cited
1992
Inhibition of cultured vascular smooth muscle cell migration by simvastatin (MK-733).
Y. Hidaka
,
T. Eda
,
M. Yonemoto
,
T. Kamei
Atherosclerosis
1992
Corpus ID: 40347889
1991
1991
Hypolipidemic effects of NB-598 in dogs.
M. Horie
,
Y. Sawasaki
,
+4 authors
T. Kamei
Atherosclerosis
1991
Corpus ID: 45721956
Highly Cited
1989
Highly Cited
1989
Preventive effect of MK-733 (simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits.
M. Kobayashi
,
F. Ishida
,
+4 authors
T. Kamei
Japanese journal of pharmacology
1989
Corpus ID: 11012759
MK-733 was found to prevent an increase of serum cholesterol levels in cholesterol-fed rabbits, and lovastatin also markedly…
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Highly Cited
1988
Highly Cited
1988
Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans.
H. Kempen
,
J. Glatz
,
J. G. Gevers Leuven
,
H. A. van der Voort
,
M. Katan
Journal of lipid research
1988
Corpus ID: 8247052
The power of serum lathosterol concentration as an indicator of whole-body cholesterol synthesis was investigated in 47 human…
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Highly Cited
1988
Highly Cited
1988
Simvastatin (MK-733): a potent cholesterol synthesis inhibitor in heterozygous familial hypercholesterolaemia.
M. Mol
,
D. Erkelens
,
J. G. Gevers Leuven
,
J. Schouten
,
A. Stalenhoef
Atherosclerosis
1988
Corpus ID: 23544077
1987
1987
Effects of MK‐733 on plasma lipid and lipoprotein levels in subjects with hypercholesterolaemia
L. Simons
,
P. Nestel
,
G. Calvert
,
Carry Jennings
The Medical journal of Australia
1987
Corpus ID: 22807569
MK‐733, which is a competitive inhibitor of the rate‐limiting step in cholesterol biosynthesis, or a matching placebo was…
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Review
1987
Review
1987
3-Hydroxy-3-methylglutaryl--coenzyme A reductase inhibitors in the treatment of hypercholesterolemia.
J. Hoeg
,
H. Brewer
JAMA
1987
Corpus ID: 21403419
A new class of drugs, which inhibit de novo cholesterol biosynthesis, significantly reduces the blood cholesterol concentrations…
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Highly Cited
1986
Highly Cited
1986
EFFECTS OF SYNVINOLIN (MK-733) ON PLASMA LIPIDS IN FAMILIAL HYPERCHOLESTEROLAEMIA
M. Mol
,
J. Leuven
,
D. Erkelens
,
T. A. Schouten
,
A. Stalenhoef
The Lancet
1986
Corpus ID: 34908117
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