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NB-598: a potent competitive inhibitor of squalene epoxidase.
Determination of serum glutamate oxaloacetate transaminase and glutamate pyruvate transaminase by using L-glutamate oxidase.
The GOT and GPT activities obtained by this method were well correlated with those obtained by the Centrifichem System 400 method.
Purification of 3beta-hydroxysteroid oxidase of Streptomyces violascens origin by affinity chromatography on cholesterol.
Structure-activity relationship in O-glucuronidation of indolocarbazole analogs.
- N. Takenaga, M. Ishii, T. Kamei, T. Yasumori
- Chemistry, BiologyDrug metabolism and disposition: the biological…
- 1 May 2002
Results suggest that a molecular length less than 14.5 A may be required for a substrate to interact with the active site of UDP-glucuronosyltransferase (UGT) and to further characterize the glucuronidation of indolocarbazole analogs, compound 1 was used as a representative compound to assess expressed human UGTs.
Regulation of squalene epoxidase in HepG2 cells.
L-Glutamate Oxidase from Streptomyces violascens. II. Properties
L-Glutamate oxidase was used in a specific and sensitive determination procedure for L-glutamic acid and produced α-ketoglutaric acid, NH3 and hydrogen peroxide according to the following schema.
L-Glutamate Oxidase from Streptomyces violascens. I. Production, Isolation and Some Properties
L-Glutamate oxidase, a novel L-glutamic acid oxidizing enzyme, has been found in the culture broth of Streptomyces violascens and exhibited a characteristic flavoprotein spectrum.
Absorption, Distribution, Excretion, and Sex Differences in the Disposition of the Antiosteolytic Agent, Alendronate after Oral Administration in Rats
The data indicated that the oral absorption of alendronate was very low, and that the drug distributed and accumulated selectively in the target site, the bone tissue, which was similar to or less than that in the plasma.
Preventive effect of MK-733 (simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits.
MK-733 was found to prevent an increase of serum cholesterol levels in cholesterol-fed rabbits, and lovastatin also markedly inhibited their increase, and it slightly affected the high density cholesterol levels.