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Selective Estrogen Receptor Modulators

Known as: Selective Estrogen Receptor Modifying Agents, selective estrogen receptor modulator (SERM), Selective Estrogen Receptor Modulator 
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an… 
National Institutes of Health

Related topics

Related topics

19 relations
Bone Density Conservation AgentsEstrogen Agonist/Antagonist [EPC]Estrogen AntagonistsIn Blood

Narrower (10)

ClomipheneEnclomipheneLY 117018Raloxifene

Broader (1)

Hormones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
ERβ-selective SERMs produce mnemonic-enhancing effects in the inhibitory avoidance and water maze tasks
Highly Cited
2005
Highly Cited
2005
Influence of estrogen therapy at conventional and high doses on the degree of mineralization of iliac bone tissue: a quantitative microradiographic analysis in postmenopausal women.
Review
2003
Review
2003
Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients
Review
2001
Review
2001
The Past, Present, and Future of Selective Estrogen Receptor Modulation
Abstract: The recognition of selective estrogen receptor modulation in the mid‐1980s provided a unique opportunity to develop… 
Review
2001
Review
2001
EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium
Review
2001
Review
2001
Tamoxifen to raloxifene and beyond.
2001
2001
Raloxifene and estrogen reduces progression of advanced atherosclerosis--a study in ovariectomized, cholesterol-fed rabbits.
2001
2001
Proliferative Lesions of Ovarian Granulosa Cells and Reversible Hormonal Changes Induced in Rats by a Selective Estrogen Receptor Modulator
This study assessed the effects of raloxifene, a selective estrogen receptor modulator (SERM), on ovarian morphology and… 
Review
1999
Review
1999
Selective estrogen receptor modulators: tissue selectivity and differential uterine effects.
Selective estrogen receptor modulators (SERMs) are compounds that bind to estrogen receptors and produce estrogen-like (agonist… 
1996
1996
The effect of a selective estrogen receptor modulator on the progression of spontaneous autoimmune disease in MRL lpr/lpr mice.
The MRL lpr/lpr mouse strain is an animal model for the autoimmune disorder systemic lupus erythematosus (SLE). Pathologic… 
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