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Enclomiphene

Known as: (E)-2-(p-(2-Chloro-1,2-Diphenylvinyl)phenoxy)triethylamine, En-Clomiphene, trans-Clomiphene 
The trans-isomer of clomiphene citrate (CC). Enclomiphene has a higher rate of clearance and is less active than the cis-isomer, cis-clomiphene… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (1)

Androxal
Enclomiphene CitrateIn BloodZuclomifene CitrateZuclomiphene

Broader (3)

Estrogen AntagonistsFertility Agents, FemaleSelective Estrogen Receptor Modulators

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Differential responses of estrogen target tissues in rats including bone to clomiphene, enclomiphene, and zuclomiphene.
The substituted triphenylethylene antiestrogen clomiphene (CLO) prevents cancellous bone loss in ovariectomized (OVX'd) rats… 
1996
1996
Multivariate analysis of capillary electrophoresis separation conditions for Z-E isomers of clomiphene.
1995
1995
Clomiphene citrate and neural tube defects: a pooled analysis of controlled epidemiologic studies and recommendations for future studies.
1987
1987
Effect of clomiphene isomers on oestradiol synthesis in cultured human granulosa cells.
The effects of en-clomiphene and zu-clomiphene (10(-7) - 10(-5) M) on oestradiol synthesis in human granulosa cells were studied… 
1982
1982
The inhibition of the estrogen receptor's positive cooperative [3H]estradiol binding by the antagonist, clomiphene.
1981
1981
Agonist and antagonist activity of en-clomiphene upon oestrogen-mediated events in the uterus, pituitary gland and brain of the rat.
The oestrogen agonist and antagonist activity of a single dose of en-clomiphene (0.5--50 mg/kg) was studied in peripheral and… 
Highly Cited
1981
Highly Cited
1981
Agonistic and antagonistic effects of clomiphene citrate and its isomers.
The agonistic and antagonistic properties of clomiphene citrate (CL) and its isomers were examined in the rat uterus. Immature… 
1979
1979
The effects of antioestrogens on the oestrogen receptor.
1972
1972
Aspects on the mode of action of antiestrogens and antiprogestogens.
Most so-called antiestrogens are ‘estrogenic’ in the mouse uterine growth test and in the Allen-Doisy test (in mice or rats… 
1972
1972
Studies on the anti-oestrogenic and oestrogen-like action of clomiphene citrate animal experiments.
The anti-oestrogenic and oestrogen-like potencies of clomiphene citrate are presumably mainly responsible for the mode of action… 
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