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SYP gene

Known as: MRX96, SYNAPTOPHYSIN, SYP 
This gene is involved in vesicle targeting and synaptic plasticity.
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensLigand BindingMembrane Protein TrafficMolecular Transport

Papers overview

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Highly Cited
2006
Highly Cited
2006
Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein
The amyloid precursor protein (APP) is critical in the pathogenesis of Alzheimer's disease. The question of its normal biological… 
Highly Cited
2004
Highly Cited
2004
Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain.
CONTEXT The schizophrenia-susceptibility gene dysbindin (DTNBP1 on 6p22.3) encodes a neuronal protein that binds to beta… 
Highly Cited
2000
Highly Cited
2000
Circuit-Specific Alterations in Hippocampal Synaptophysin Immunoreactivity Predict Spatial Learning Impairment in Aged Rats
The present study examined the long-standing concept that changes in hippocampal circuitry contribute to age-related learning… 
Highly Cited
1998
Highly Cited
1998
Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders.
The precursor of the non-Abeta component of Alzheimer's disease amyloid (NACP) (also known as a-synuclein) is a presynaptic… 
Highly Cited
1998
Highly Cited
1998
Enhanced neocortical neural sprouting, synaptogenesis, and behavioral recovery with D-amphetamine therapy after neocortical infarction in rats.
BACKGROUND AND PURPOSE D-Amphetamine administration increases behavioral recovery after various cortical lesions including… 
Highly Cited
1995
Highly Cited
1995
Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.
The synaptic vesicle protein synaptobrevin (VAMP) has recently been implicated as one of the key proteins involved in exocytotic… 
Highly Cited
1995
Highly Cited
1995
Morphological analysis of dendritic spine development in primary cultures of hippocampal neurons
We monitored developmental alterations in the morphology of dendritic spines in primary cultures of hippocampal neurons using… 
Highly Cited
1993
Highly Cited
1993
Quantitative synaptic alterations in the human neocortex during normal aging
We quantified the synaptic population density in the frontal cortex of 25 individuals without dementia 16 to 98 years old, using… 
Highly Cited
1989
Highly Cited
1989
Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain.
A protein with an apparent mol. wt of 18,000 daltons (synaptobrevin) was identified in synaptic vesicles from rat brain. Some of… 
Highly Cited
1986
Highly Cited
1986
Synaptophysin: a marker protein for neuroendocrine cells and neoplasms.
Synaptophysin is an integral membrane glycoprotein (Mr 38,000) that occurs in presynaptic vesicles of neurons and in similar… 
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