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SYP gene

Known as: MRX96, SYNAPTOPHYSIN, SYP 
This gene is involved in vesicle targeting and synaptic plasticity.
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensLigand BindingMembrane Protein TrafficMolecular Transport
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Papers overview

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Review
2019
Review
2019
Therapeutic potentials of plant iridoids in Alzheimer's and Parkinson's diseases: A review.
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common age-related neurodegenerative disorders, affecting… Expand
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Highly Cited
2011
Highly Cited
2011
Normal gut microbiota modulates brain development and behavior
Microbial colonization of mammals is an evolution-driven process that modulate host physiology, many of which are associated with… Expand
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Highly Cited
2007
Highly Cited
2007
Experience
Perhaps the most enjoyable part of editing a medical journal is the steady flow of warm, fuzzy, feel-good letters from authors… Expand
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Highly Cited
2006
Highly Cited
2006
Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation
Mutations in the genes for amyloid precursor protein (APP) and presenilins (PS1, PS2) increase production of β-amyloid 42 (Aβ42… Expand
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Highly Cited
2004
Highly Cited
2004
Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain
Background: Pathologic changes in the Alzheimer disease (AD) brain occur in a hierarchical neuroanatomical pattern affecting… Expand
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Highly Cited
2001
Highly Cited
2001
Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice
Inhibition of neocortical beta-amyloid (Abeta) accumulation may be essential in an effective therapeutic intervention for… Expand
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Highly Cited
2001
Highly Cited
2001
Altered expression of synaptic proteins occurs early during progression of Alzheimer’s disease
The expression levels of three synaptic proteins (synaptophysin, synaptotagmin, and growth-associated protein 43 [GAP43]) in AD… Expand
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Highly Cited
1999
Highly Cited
1999
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease.
We have characterized amyloid beta peptide (Abeta) concentration, Abeta deposition, paired helical filament formation… Expand
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Highly Cited
1995
Highly Cited
1995
The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
Non-A beta component of Alzheimer's disease amyloid (NAC) is the second component in the amyloid from brain tissue of patients… Expand
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Highly Cited
1990
Highly Cited
1990
Developmental history of the transient subplate zone in the visual and somatosensory cortex of the macaque monkey and human brain.
The cytological organization and the timetable of emergence and dissolution of the transient subplate zone subjacent to the… Expand
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