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SUV39H1 wt Allele

Known as: Suppressor of variegation 3-9 homolog 1 (Drosophila) wt Allele, KMT1A, SUV39H 
Human SUV39H1 is located in the vicinity of Xp11.23 and is approximately 12 kb in length. This allele, which encodes histone-lysine N… 
National Institutes of Health

Related topics

Related topics

10 relations
EZH2 protein, humanGene ExpressionMethylationProtein methylation

Narrower (1)

SETMAR protein, human

Broader (1)

SUV39H1 gene

Papers overview

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Highly Cited
2018
Highly Cited
2018
ALDH2 protects against high fat diet-induced obesity cardiomyopathy and defective autophagy: role of CaM kinase II, histone H3K9 methyltransferase SUV39H, Sirt1, and PGC-1α deacetylation
Background and aimsUncorrected obesity contributes to cardiac remodeling and contractile dysfunction although the underlying… 
Highly Cited
2013
Highly Cited
2013
β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications
Multiple cis-elements surrounding the β-globin gene locus combine to target this locus to the nuclear periphery through at least… 
2011
2011
Histone methyltransferase KMT1A restrains entry of alveolar rhabdomyosarcoma cells into a myogenic differentiated state.
Alveolar rhabdomyosarcoma (ARMS) is an aggressive pediatric muscle cancer, which arrested during the process of skeletal muscle… 
2010
2010
SUV39h-independent association of HP1β with fibrillarin-positive nucleolar regions
Heterochromatin protein 1 (HP1), which binds to sites of histone H3 lysine 9 (H3K9) methylation, is primarily responsible for… 
2010
2010
DDB2, an Essential Mediator of Premature Senescence
ABSTRACT Reactive oxygen species (ROS) is critical for premature senescence, a process significant in tumor suppression and… 
Highly Cited
2008
Highly Cited
2008
The Suv39h–HP1 histone methylation pathway is dispensable for enrichment and protection of cohesin at centromeres in mammalian cells
Sister chromatids are physically connected by cohesin complexes. This sister chromatid cohesion is essential for the… 
Highly Cited
2007
Highly Cited
2007
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination
Mammalian telomeres have heterochromatic features, including trimethylated histone H3 at lysine 9 (H3K9me3) and trimethylated… 
Highly Cited
2006
Highly Cited
2006
Prohibitin Facilitates Cellular Senescence by Recruiting Specific Corepressors To Inhibit E2F Target Genes
ABSTRACT Prohibitin is a growth regulatory gene that has pleiotropic functions in the nucleus, mitochondria, and cytoplasmic… 
Highly Cited
2004
Highly Cited
2004
A Suv39h‐dependent mechanism for silencing S‐phase genes in differentiating but not in cycling cells
The Rb/E2F complex represses S‐phase genes both in cycling cells and in cells that have permanently exited from the cell cycle… 
2004
2004
Plants Contain a High Number of Proteins Showing Sequence Similarity to the Animal SUV39H Family of Histone Methyltransferases
Abstract: The SET domain, first identified within and named after proteins encoded by three Drosophila genes [Su(var)3–9, E(z… 
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