Methylation

Known as: Methylations 
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
It is not yet known whether DNA methylation levels can be used to accurately predict age across a broad spectrum of human tissues… (More)
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Highly Cited
2011
Highly Cited
2011
SUMMARY A combination of bisulfite treatment of DNA and high-throughput sequencing (BS-Seq) can capture a snapshot of a cell's… (More)
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Highly Cited
2010
Highly Cited
2010
Although it is known that the methylation of DNA in 5′ promoters suppresses gene expression, the role of DNA methylation in gene… (More)
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Highly Cited
2010
Highly Cited
2010
Eukaryotic cytosine methylation represses transcription but also occurs in the bodies of active genes, and the extent of… (More)
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Review
2008
Review
2008
The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine. To understand the biological… (More)
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Highly Cited
2007
Highly Cited
2007
Mammals use DNA methylation for the heritable silencing of retrotransposons and imprinted genes and for the inactivation of the X… (More)
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Review
2004
Review
2004
DNA methylation is an important regulator of gene transcription, and its role in carcinogenesis has been a topic of considerable… (More)
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Highly Cited
2002
Highly Cited
2002
MOTIVATION DNA methylation is an epigenetic mechanism of gene regulation. Bisulfite- conversion-based PCR methods, such as… (More)
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Highly Cited
2000
Highly Cited
2000
Cytosine-5 DNA methylation occurs in the context of CpG dinucleotides in vertebrates. Aberrant methylation of CpG islands in… (More)
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Highly Cited
1996
Highly Cited
1996
Precise mapping of DNA methylation patterns in CpG islands has become essential for understanding diverse biological processes… (More)
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