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Methylation
Known as:
Methylations
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections…
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National Institutes of Health
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Related topics
Related topics
50 relations
Adenosylhomocysteinase, human
BHMT gene
BHMT2 protein, human
CARM1 gene
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Broader (1)
Alkylation
Narrower (1)
methyltransferase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Dynamic DNA methylation across diverse human cell lines and tissues
K. Varley
,
Jason Gertz
,
+10 authors
R. Myers
Genome Research
2013
Corpus ID: 14264725
As studies of DNA methylation increase in scope, it has become evident that methylation has a complex relationship with gene…
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Highly Cited
2011
Highly Cited
2011
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
S. Shukla
,
Erşen Kavak
,
+6 authors
Shalini Oberdoerffer
Nature
2011
Corpus ID: 4332327
Alternative splicing of pre-messenger RNA is a key feature of transcriptome expansion in eukaryotic cells, yet its regulation is…
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Highly Cited
2010
Highly Cited
2010
Direct detection of DNA methylation during single-molecule, real-time sequencing
B. Flusberg
,
Dale R. Webster
,
+5 authors
S. Turner
Nature Methods
2010
Corpus ID: 5159341
We describe the direct detection of DNA methylation, without bisulfite conversion, through single-molecule, real-time (SMRT…
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Highly Cited
2006
Highly Cited
2006
High-throughput DNA methylation profiling using universal bead arrays.
M. Bibikova
,
Zhenwu Lin
,
+14 authors
Jian-Bing Fan
Genome Research
2006
Corpus ID: 21936603
We have developed a high-throughput method for analyzing the methylation status of hundreds of preselected genes simultaneously…
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Highly Cited
2001
Highly Cited
2001
Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos
W. Dean
,
Fátima Santos
,
+4 authors
W. Reik
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 21380232
Mouse embryos undergo genome-wide methylation reprogramming by demethylation in early preimplantation development, followed by…
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Highly Cited
1999
Highly Cited
1999
The FLF MADS Box Gene: A Repressor of Flowering in Arabidopsis Regulated by Vernalization and Methylation
C. Sheldon
,
J. Burn
,
+4 authors
E. Dennis
The Plant Cell
1999
Corpus ID: 10366150
A MADS box gene, FLF (for FLOWERING LOCUS F), isolated from a late-flowering, T-DNA–tagged Arabidopsis mutant, is a semidominant…
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Highly Cited
1998
Highly Cited
1998
Aging and DNA methylation in colorectal mucosa and cancer.
N. Ahuja
,
Qing Li
,
Avinash Mohan
,
S. Baylin
,
J. Issa
Cancer Research
1998
Corpus ID: 6508162
DNA methylation of promoter-associated CpG islands may function as an alternate mechanism of silencing tumor suppressor genes in…
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Highly Cited
1993
Highly Cited
1993
Role for DNA methylation in genomic imprinting
E. Li
,
C. Beard
,
R. Jaenisch
Nature
1993
Corpus ID: 4311091
Highly Cited
1981
Highly Cited
1981
Sequence specificity of methylation in higher plant DNA
Y. Gruenbaum
,
T. Naveh-Many
,
H. Cedar
,
A. Razin
Nature
1981
Corpus ID: 4254836
Although plant DNA has a high content of 5-methylcytosine (5mC1) very little is known about the distribution of this modification…
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Review
1980
Review
1980
Phospholipid methylation and biological signal transmission.
F. Hirata
,
J. Axelrod
Science
1980
Corpus ID: 21769940
Many types of cells methylate phospholipids using two methyltransferase enzymes that are asymmetrically distributed in membranes…
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