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Adenosylhomocysteinase, human

Known as: Adenosylhomocysteinase, S-Adenosylhomocysteine Hydrolase, AHCY 
Adenosylhomocysteinase (432 aa, ~48 kDa) is encoded by the human AHCY gene. This protein plays a role in amino acid modification.
National Institutes of Health

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Related topics

8 relations
AHCY geneAHCY wt AlleleAmino Acid BiosynthesisCytoplasmic matrix
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Broader (1)

Adenosylhomocysteinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Immunization of mice with recombinant S-adenosyl-L-homocysteine hydrolase protein confers protection against Brucella melitensis infection.
Due to drawbacks of live attenuated vaccines, much attention has been focused on screening Brucella-protective antigens as… Expand
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Highly Cited
2009
Highly Cited
2009
Proteome changes induced by aluminium stress in tomato roots.
Growth inhibition in acid soils due to Al stress affects crop production worldwide. To understand mechanisms in sensitive crops… Expand
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Review
2007
Review
2007
Structure and function of S-adenosylhomocysteine hydrolase
In mammals, S-adenosylhomocysteine hydrolase (AdoHcyase) is the only known enzyme to catalyze the breakdown of S… Expand
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2005
2005
S-Adenosylhomocysteine Metabolism in Different Cell Lines: Effect of Hypoxia and Cell Density
Background/Aims: The methylation potential (MP) is defined as the ratio of S-adenosylmethionine (AdoMet) to S… Expand
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Review
2004
Review
2004
S-Adenosylhomocysteine hydrolase as a target for intracellular adenosine action.
S-Adenosylhomocysteine hydrolase (AdoHcyase) controls intracellular levels of S-adenosylhomocysteine (AdoHcy). AdoHcy is a potent… Expand
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1999
1999
Crystal structure of S-adenosylhomocysteine hydrolase from rat liver.
The crystal structure of rat liver S-adenosyl-L-homocysteine hydrolase (AdoHcyase, EC 3.3.1.1) which catalyzes the reversible… Expand
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1993
1993
Selective inhibition of T cell activation by an inhibitor of S-adenosyl-L-homocysteine hydrolase.
Defects in the enzymes involved in the pathway of S-adenosylmethionine (AdoMet) metabolism, or inhibition of those enzymes… Expand
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1984
1984
Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin.
Selective failure of lymphoid development occurs in genetic deficiency of adenosine deaminase (ADA). We examined the in vivo… Expand
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1980
1980
Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation.
Accumulation of dATP derived from 2'-deoxyadenosine (dAdo), causing inhibition of ribonucleotide reductase and depletion of the… Expand
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1971
1971
Inhibition of transmethylations of biogenic amines by S-adenosylhomocysteine. Enhancement of transmethylation by adenosylhomocysteinase.
Abstract The supernatant fraction of brain homogenate stimulates partially purified phenylethanolamine N-methyltransferase… Expand
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