FAQ

Adenosylhomocysteinase, human

Known as: Adenosylhomocysteinase, S-Adenosylhomocysteine Hydrolase, AHCY 
Adenosylhomocysteinase (432 aa, ~48 kDa) is encoded by the human AHCY gene. This protein plays a role in amino acid modification.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
0246819752017

Related topics

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9 relations
AHCY geneAHCY wt AlleleAmino Acid BiosynthesisCytoplasmic matrix
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Broader (1)

Adenosylhomocysteinase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Adenosylhomocysteinase, human
Hydrolysis
Methylation
Cytoplasmic matrix
Adenosylhomocysteinase
AHCY gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase.
Hepatic steatosis and liver degeneration are prominent features of the zebrafish ducttrip (dtp) mutant phenotype. Positional… (More)
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2008
2008
Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm.
BACKGROUND Previous studies suggested an association between abdominal aortic aneurysm (AAA) and hyperhomocysteinaemia, a complex… (More)
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2005
2005
Comparative gene expression analysis of ovarian carcinoma and normal ovarian epithelium by serial analysis of gene expression.
Despite the poor prognosis of ovarian cancer and the importance of early diagnosis, there are no reliable noninvasive biomarkers… (More)
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2003
2003
Application of disease-associated differentially expressed genes – Mining for functional candidate genes for mastitis resistance in cattle
In this study the mRNA differential display method was applied to identify mastitis-associated expressed DNA sequences based on… (More)
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2002
2002
Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.
S-Adenosylhomocysteine hydrolase (AdoHcyase) catalyzes the hydrolysis of S-adenosylhomocysteine to form adenosine and… (More)
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2001
2001
Contribution of enzymic alpha, gamma-elimination reaction in detoxification pathway of selenomethionine in mouse liver.
The objective of this study was to clarify the detoxification pathways of selenomethionine (SeMet) in mouse liver. It has been… (More)
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1999
1999
Crystal structure of S-adenosylhomocysteine hydrolase from rat liver.
The crystal structure of rat liver S-adenosyl-L-homocysteine hydrolase (AdoHcyase, EC 3.3.1.1) which catalyzes the reversible… (More)
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1993
1993
Selective inhibition of T cell activation by an inhibitor of S-adenosyl-L-homocysteine hydrolase.
Defects in the enzymes involved in the pathway of S-adenosylmethionine (AdoMet) metabolism, or inhibition of those enzymes… (More)
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1984
1984
Homocysteine in tissues of the mouse and rat.
A method for the determination of L-homocysteine (Hcy) in tissues is described, which involves adsorption of adenosine and S… (More)
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1979
1979
S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.
The human lymphoblast line WI-L2 is subject to growth inhibition by a combination of the adenosine deaminase (ADA; adenosine… (More)
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