methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule. [ISBN:0198506732]
National Institutes of Health

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Methylationmethylase activity
Methyltransferase

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2014
2014
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
SET domain containing (lysine methyltransferase) 7 (SETD7) is implicated in multiple signaling and disease related pathways with… (More)
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2013
2013
Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9.
PRDM9, a histone lysine methyltransferase, is a key determinant of the localization of meiotic recombination hot spots in humans… (More)
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Highly Cited
2011
Highly Cited
2011
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
Protein lysine methyltransferases G9a and GLP modulate the transcriptional repression of a variety of genes via dimethylation of… (More)
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2009
2009
Inhibition of SUV39H1 methyltransferase activity by DBC1.
SUV39H1 is a histone H3K9-specific methyltransferase important for heterochromatin formation, regulation of gene expression, and… (More)
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2004
2004
The N-terminus of Drosophila SU(VAR)3-9 mediates dimerization and regulates its methyltransferase activity.
In most eukaryotes, the histone methyltransferase SU(VAR)3-9 and its orthologues play a major role in the function of centromeric… (More)
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2002
2002
Relevance of thiopurine methyltransferase activity in inflammatory bowel disease patients maintained on low-dose azathioprine.
BACKGROUND It is well-recognized that patients with low thiopurine methyltransferase activity are more susceptible to the… (More)
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1991
1991
Expression of Sindbis virus nsP1 and methyltransferase activity in Escherichia coli.
We have constructed two plasmids, pSR5-42 and pSR5-Toto, which under lac control expressed the SVLM21 and the SVToto forms… (More)
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1990
1990
Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae.
Membrane extracts of sterile Saccharomyces cerevisiae strains containing the a-specific ste14 mutation lack a farnesyl cysteine C… (More)
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1988
1988
Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat.
Catechol-O-methyltransferase (COMT) has an important role in the extraneuronal inactivation of catecholamine neurotransmitters… (More)
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1985
1985
Inhibition of glycine N-methyltransferase activity by folate derivatives: implications for regulation of methyl group metabolism.
Glycine N-methyltransferase, an enzyme that uses S-adenosylmethionine to methylate glycine with the production of sarcosine, was… (More)
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