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Fungal secondary metabolism has become an important research topic with great biomedical and biotechnological value. In the… Expand The sequence and the structure of DNA methyltransferase-2 (Dnmt2) bear close affinities to authentic DNA cytosine… Expand Large-genome eukaryotes use heritable cytosine methylation to silence promoters, especially those associated with transposons and… Expand MLL, the human homolog of Drosophila trithorax, maintains Hox gene expression in mammalian embryos and is rearranged in human… Expand DNA methylation is involved in epigenetic processes such as X-chromosome inactivation, imprinting and silencing of transposons… Expand Heterochromatin protein 1 (HP1) is localized at heterochromatin sites where it mediates gene silencing. The chromo domain of HP1… Expand The biological significance of 5-methylcytosine was in doubt for many years, but is no longer. Through targeted mutagenesis in… Expand Gene targeting in embryonic stem (ES) cells has been used to mutate the murine DNA methyltransferase gene. ES cell lines… Expand Thiopurine methyltransferase (TPMT) catalyzes thiopurine S-methylation, an important metabolic pathway for drugs such as 6… Expand The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6.
The rate of autoxidation… Expand