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Methyltransferase

Known as: transmethylase, Methyltransferases, EC 2.1.1 
A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1… 
National Institutes of Health

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Narrower (42)

BAMT protein, Antirrhinum majusBtaB protein, Rhodobacter sphaeroidesCatechol O-MethyltransferaseEfm6 protein, S cerevisiae
Enzyme GeneIn BloodMETTL3 geneMRM3 gene

Papers overview

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Highly Cited
2010
Highly Cited
2010
Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
In myelodysplastic syndromes (MDS), deletions of chromosome 7 or 7q are common and correlate with a poor prognosis. The relevant… 
Highly Cited
2007
Highly Cited
2007
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.
Alterations in cytosine methylation patterns are usually observed in human tumors. The consequences of altered cytosine… 
Highly Cited
2006
Highly Cited
2006
Arsenic detoxification and evolution of trimethylarsine gas by a microbial arsenite S-adenosylmethionine methyltransferase
In this article, a mechanism of arsenite [As(III)]resistance through methylation and subsequent volatization is described… 
Highly Cited
2005
Highly Cited
2005
Myc represses transcription through recruitment of DNA methyltransferase corepressor
The Myc transcription factor is an essential mediator of cell growth and proliferation through its ability to both positively and… 
Highly Cited
2003
Highly Cited
2003
Arabidopsis MET1 cytosine methyltransferase mutants.
We describe the isolation and characterization of two missense mutations in the cytosine-DNA-methyltransferase gene, MET1, from… 
Highly Cited
2002
Highly Cited
2002
Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes
Many plant, animal, and fungal genomes contain cytosine DNA methylation in asymmetric sequence contexts (CpHpH, H = A, T, C… 
Highly Cited
2002
Highly Cited
2002
Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements
ABSTRACT We used mouse embryonic stem (ES) cells with systematic gene knockouts for DNA methyltransferases to delineate the roles… 
Highly Cited
1998
Highly Cited
1998
Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior.
Catechol-O-methyltransferase (COMT) is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines… 
Highly Cited
1994
Highly Cited
1994
Crystal structure of catechol O-methyltransferase
CATECHOL O-methyltransferase (COMT, EC 2.1.1.6) is important in the central nervous system because it metabolizes catecholamine… 
Review
1993
Review
1993
Protein kinase C isoenzymes: divergence in signal transduction?
The development and life-time of multicellular eukaryotic organisms represents a complex interplay of numerous proliferation and… 
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