Methyltransferase

Known as: transmethylase, Methyltransferases, EC 2.1.1 
A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Abnormalities of chromosome 7q are common in myeloid malignancies, but no specific target genes have yet been identified. Here… (More)
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Highly Cited
2010
Highly Cited
2010
In myelodysplastic syndromes (MDS), deletions of chromosome 7 or 7q are common and correlate with a poor prognosis. The relevant… (More)
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Highly Cited
2006
Highly Cited
2006
The sequence and the structure of DNA methyltransferase-2 (Dnmt2) bear close affinities to authentic DNA cytosine… (More)
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Review
2005
Review
2005
Large-genome eukaryotes use heritable cytosine methylation to silence promoters, especially those associated with transposons and… (More)
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Highly Cited
2004
Highly Cited
2004
Imprinted genes are epigenetically marked during gametogenesis so that they are exclusively expressed from either the paternal or… (More)
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Highly Cited
2003
Highly Cited
2003
Monamines subserve many critical roles in the brain, and monoaminergic drugs such as amphetamine have a long history in the… (More)
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Review
2000
Review
2000
The biological significance of 5-methylcytosine was in doubt for many years, but is no longer. Through targeted mutagenesis in… (More)
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Highly Cited
2000
Highly Cited
2000
Current evidence indicates that methylation of cytosine in mammalian DNA is restricted to both strands of the symmetrical… (More)
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Highly Cited
2000
Highly Cited
2000
The DNA methyltransferase Dnmt1 is responsible for cytosine methylation in mammals and has a role in gene silencing. DNA… (More)
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Highly Cited
1992
Highly Cited
1992
Tissue-specific patterns of methylated deoxycytidine residues in the mammalian genome are preserved by postreplicative… (More)
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